SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ko8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 1ko8 GLUCONATE KINASE
(Escherichia
coli) 		4 / 5 HIS A  33
ALA A  35
SER A  83
HIS A   8
 None
 1.33A 1errA-1ko8A:
0.0
1errB-1ko8A:
0.0		 1errA-1ko8A:
19.76
1errB-1ko8A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 1ko8 GLUCONATE KINASE
(Escherichia
coli) 		5 / 12 GLY A  39
LEU A  84
LEU A  37
VAL A  24
ILE A 108
 None
 1.13A 1zq9A-1ko8A:
undetectable		 1zq9A-1ko8A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ko8 GLUCONATE KINASE
(Escherichia
coli) 		5 / 12 GLY A  18
ALA A 123
LEU A 160
VAL A 163
ILE A 156
 6PG  A 502 (-3.7A)
None
None
None
None
 0.86A 3adxB-1ko8A:
0.0		 3adxB-1ko8A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 1ko8 GLUCONATE KINASE
(Escherichia
coli) 		4 / 6 ASP A  38
SER A  19
ALA A  25
PHE A  36
 MG  A 201 ( 4.2A)
None
None
None
 1.23A 4nedA-1ko8A:
undetectable		 4nedA-1ko8A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1ko8 GLUCONATE KINASE
(Escherichia
coli) 		4 / 4 ILE A 168
LEU A  84
HIS A  33
ALA A  34
 None
 1.04A 6ck2C-1ko8A:
undetectable
6ck2D-1ko8A:
undetectable		 6ck2C-1ko8A:
5.77
6ck2D-1ko8A:
11.98