SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1kon PROTEIN YEBC
(Escherichia
coli) 		4 / 8 ILE A 220
LEU A 223
PHE A 117
GLY A  89
 None
 1.08A 1os6A-1konA:
undetectable		 1os6A-1konA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 1kon PROTEIN YEBC
(Escherichia
coli) 		3 / 3 ASP A 166
TYR A 165
GLU A 237
 None
 0.73A 1vm1A-1konA:
undetectable		 1vm1A-1konA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 1kon PROTEIN YEBC
(Escherichia
coli) 		5 / 10 LEU A  32
ILE A  28
ILE A  86
GLU A 100
LEU A 102
 None
 1.23A 1wopA-1konA:
2.5		 1wopA-1konA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 1kon PROTEIN YEBC
(Escherichia
coli) 		4 / 7 PHE A 117
ASN A 123
TYR A  90
VAL A 130
 None
 1.38A 1wu8A-1konA:
undetectable
1wu8C-1konA:
undetectable		 1wu8A-1konA:
24.00
1wu8C-1konA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 1kon PROTEIN YEBC
(Escherichia
coli) 		5 / 11 LEU A 219
LEU A 223
ARG A  13
GLN A  17
ILE A  97
 None
 1.09A 2qjuA-1konA:
0.7		 2qjuA-1konA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 1kon PROTEIN YEBC
(Escherichia
coli) 		4 / 7 VAL A 163
ASP A 167
TYR A 173
ILE A 201
 None
 1.01A 3avpA-1konA:
0.0		 3avpA-1konA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 1kon PROTEIN YEBC
(Escherichia
coli) 		4 / 6 ALA A 213
ILE A 238
HIS A  12
HIS A 234
 None
 1.06A 3nneG-1konA:
undetectable		 3nneG-1konA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1kon PROTEIN YEBC
(Escherichia
coli) 		4 / 7 ILE A 220
LEU A 223
PHE A 117
GLY A  89
 None
 1.04A 4hbfA-1konA:
0.0		 4hbfA-1konA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1kon PROTEIN YEBC
(Escherichia
coli) 		4 / 5 ASN A 107
TYR A  87
VAL A 229
LEU A 223
 None
 1.09A 6a7pA-1konA:
2.8		 6a7pA-1konA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 1kon PROTEIN YEBC
(Escherichia
coli) 		5 / 7 GLY A 122
GLY A  91
PRO A  92
GLY A  93
GLY A  94
 None
 0.83A 6ag0A-1konA:
undetectable		 6ag0A-1konA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 1kon PROTEIN YEBC
(Escherichia
coli) 		3 / 3 HIS A 234
ARG A  13
ILE A 220
 None
 0.80A 6fgdA-1konA:
undetectable		 6fgdA-1konA:
21.13