SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kp6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_A_RBFA300_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kp6	PROTEIN (TOXIN) (Ustilago maydis)	5 / 11	TYR A 44 GLY A 49 TRP A 17 LEU A 52 HIS A 64	None	1.48A	2a58A-1kp6A: undetectable 2a58E-1kp6A: undetectable	2a58A-1kp6A: 17.22 2a58E-1kp6A: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_D_RBFD303_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kp6	PROTEIN (TOXIN) (Ustilago maydis)	5 / 11	HIS A 64 TYR A 44 GLY A 49 TRP A 17 LEU A 52	None	1.46A	2a58C-1kp6A: undetectable 2a58D-1kp6A: undetectable	2a58C-1kp6A: 17.22 2a58D-1kp6A: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I5U_B_SAMB401_1 (O-METHYLTRANSFERASE)	1kp6	PROTEIN (TOXIN) (Ustilago maydis)	3 / 3	ASP A 56 PHE A 53 SER A 76	None	0.77A	3i5uB-1kp6A: undetectable	3i5uB-1kp6A: 12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_C_ACTC800_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	1kp6	PROTEIN (TOXIN) (Ustilago maydis)	3 / 3	ASP A 45 ARG A 47 ALA A 48	None	0.80A	3mbgC-1kp6A: undetectable	3mbgC-1kp6A: 20.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A58_A_RBFA300_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kp6","PROTEIN (TOXIN)","Ustilago maydis",5,"TYR A  44;GLY A  49;TRP A  17;LEU A  52;HIS A  64","None","1.48A","2a58A-1kp6A:undetectable;2a58E-1kp6A:undetectable","2a58A-1kp6A:17.22;2a58E-1kp6A:17.22"],["2A58_D_RBFD303_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kp6","PROTEIN (TOXIN)","Ustilago maydis",5,"HIS A  64;TYR A  44;GLY A  49;TRP A  17;LEU A  52","None","1.46A","2a58C-1kp6A:undetectable;2a58D-1kp6A:undetectable","2a58C-1kp6A:17.22;2a58D-1kp6A:17.22"],["3I5U_B_SAMB401_1","O-METHYLTRANSFERASE","1kp6","PROTEIN (TOXIN)","Ustilago maydis",3,"ASP A  56;PHE A  53;SER A  76","None","0.77A","3i5uB-1kp6A:undetectable","3i5uB-1kp6A:12.07"],["3MBG_C_ACTC800_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","1kp6","PROTEIN (TOXIN)","Ustilago maydis",3,"ASP A  45;ARG A  47;ALA A  48","None","0.80A","3mbgC-1kp6A:undetectable","3mbgC-1kp6A:20.80"]]