SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kph'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLN A  49
HIS A 167
GLU A 140
LYS A  52
VAL A 134
 None
CO3  A1902 (-3.8A)
CO3  A1902 ( 3.6A)
None
None
 1.37A 1j36A-1kphA:
undetectable		 1j36A-1kphA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLN A  49
HIS A 167
GLU A 140
LYS A  52
VAL A 134
 None
CO3  A1902 (-3.8A)
CO3  A1902 ( 3.6A)
None
None
 1.37A 1j36B-1kphA:
undetectable		 1j36B-1kphA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 8 THR A 168
GLY A 137
GLY A 143
PHE A 139
GLY A 203
 None
CO3  A1902 (-3.1A)
None
None
10A  A1901 (-3.7A)
 1.38A 1jhvA-1kphA:
undetectable		 1jhvA-1kphA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  16
GLY A  74
SER A  96
GLY A 137
HIS A 141
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.2A)
None
CO3  A1902 (-3.1A)
SAH  A1900 (-4.4A)
 0.82A 1nbhB-1kphA:
15.4		 1nbhB-1kphA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 PHE A 151
LEU A 153
ALA A 154
THR A 168
PHE A 139
 None
 1.04A 1og5A-1kphA:
0.2		 1og5A-1kphA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  16
GLY A  74
ILE A 136
HIS A 141
PHE A 142
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.2A)
SAH  A1900 (-4.4A)
SAH  A1900 ( 4.6A)
 1.03A 1ve3A-1kphA:
17.1		 1ve3A-1kphA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  16
GLY A  74
ILE A 136
HIS A 141
PHE A 142
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.2A)
SAH  A1900 (-4.4A)
SAH  A1900 ( 4.6A)
 1.06A 1ve3B-1kphA:
16.9		 1ve3B-1kphA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_ACTB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		4 / 4 HIS A  15
PRO A 201
ASN A  11
TYR A  16
 None
None
None
SAH  A1900 ( 4.2A)
 1.48A 2f7aB-1kphA:
0.0		 2f7aB-1kphA:
22.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		11 / 12 THR A  32
TYR A  33
GLY A  72
GLY A  74
LEU A  95
GLY A 122
TRP A 123
GLU A 124
ILE A 136
ALA A 138
HIS A 141
 SAH  A1900 (-4.1A)
10A  A1901 ( 3.5A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.4A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.3A)
SAH  A1900 (-2.9A)
SAH  A1900 (-4.2A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.4A)
 0.43A 2fk8A-1kphA:
40.6		 2fk8A-1kphA:
54.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		3 / 3 SER A  34
THR A  94
GLN A  99
 SAH  A1900 ( 3.6A)
SAH  A1900 (-4.0A)
SAH  A1900 (-2.9A)
 0.22A 2fk8A-1kphA:
40.6		 2fk8A-1kphA:
54.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
GLY A  74
THR A  78
GLU A 124
HIS A 141
 SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-2.9A)
SAH  A1900 (-4.4A)
 0.81A 2gluA-1kphA:
18.0		 2gluA-1kphA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
GLY A  74
ALA A 138
HIS A 141
PHE A 142
 SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.4A)
SAH  A1900 ( 4.6A)
 0.75A 2gluB-1kphA:
18.0		 2gluB-1kphA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
THR A  32
SER A  34
LEU A  68
LEU A  62
 SAH  A1900 (-3.1A)
SAH  A1900 (-4.1A)
SAH  A1900 ( 3.6A)
None
None
 0.97A 2hw2A-1kphA:
0.0		 2hw2A-1kphA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 205
PHE A 191
ILE A 169
PHE A 273
 10A  A1901 (-3.9A)
None
10A  A1901 ( 4.7A)
None
 0.90A 2opxA-1kphA:
4.4		 2opxA-1kphA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  74
LEU A  93
LEU A  95
SER A  96
GLY A 137
 SAH  A1900 (-3.2A)
SAH  A1900 ( 4.9A)
SAH  A1900 (-4.4A)
None
CO3  A1902 (-3.1A)
 1.06A 3g2oA-1kphA:
15.7		 3g2oA-1kphA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  16
GLY A  74
LEU A  95
SER A  96
HIS A 141
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.4A)
None
SAH  A1900 (-4.4A)
 0.69A 3pfgA-1kphA:
15.0		 3pfgA-1kphA:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		3 / 3 GLY A  74
GLY A  76
THR A  78
 SAH  A1900 (-3.2A)
None
None
 0.23A 3si7B-1kphA:
undetectable		 3si7B-1kphA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 TYR A  33
HIS A  15
LEU A 243
LEU A 266
ALA A 250
 10A  A1901 ( 3.5A)
None
None
None
None
 1.06A 3vw7A-1kphA:
undetectable		 3vw7A-1kphA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
GLY A  74
THR A  94
LEU A  95
GLN A  99
 SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.0A)
SAH  A1900 (-4.4A)
SAH  A1900 (-2.9A)
 0.42A 4f84A-1kphA:
25.1		 4f84A-1kphA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		3 / 3 LYS A  85
TYR A  86
ARG A  81
 None
 1.42A 4gc9A-1kphA:
9.7		 4gc9A-1kphA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		6 / 12 TYR A  16
GLY A  72
GLY A  74
LEU A  95
SER A  96
HIS A 141
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.4A)
None
SAH  A1900 (-4.4A)
 0.73A 4krhA-1kphA:
27.7		 4krhA-1kphA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		6 / 12 TYR A  16
GLY A  72
GLY A  74
LEU A  95
SER A  96
HIS A 141
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.4A)
None
SAH  A1900 (-4.4A)
 0.74A 4krhB-1kphA:
27.8		 4krhB-1kphA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		4 / 6 GLY A 276
ILE A 208
ILE A 177
LEU A 192
 None
None
None
10A  A1901 (-3.7A)
 0.74A 4o8fB-1kphA:
undetectable		 4o8fB-1kphA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 122
GLU A 124
VAL A  12
TYR A  16
SER A 135
 SAH  A1900 (-3.2A)
SAH  A1900 (-2.9A)
SAH  A1900 (-4.9A)
SAH  A1900 ( 4.2A)
None
 1.23A 4pd9A-1kphA:
0.0		 4pd9A-1kphA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		4 / 6 THR A 168
GLU A 140
THR A 170
LEU A 166
 None
CO3  A1902 ( 3.6A)
None
None
 1.10A 4pgfA-1kphA:
4.3		 4pgfA-1kphA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  12
GLY A  72
GLY A  74
SER A  96
HIS A 141
 SAH  A1900 (-4.9A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-4.4A)
 0.90A 4qdjA-1kphA:
18.1		 4qdjA-1kphA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  74
GLY A  72
LEU A  95
ILE A 136
SER A 135
 SAH  A1900 (-3.2A)
SAH  A1900 (-3.1A)
SAH  A1900 (-4.4A)
SAH  A1900 (-4.2A)
None
 1.10A 4qtuB-1kphA:
17.0		 4qtuB-1kphA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		6 / 12 TYR A  16
GLY A  72
GLY A  74
SER A  96
ILE A 136
ALA A 138
 SAH  A1900 ( 4.2A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-4.2A)
SAH  A1900 (-3.2A)
 0.85A 4qtuB-1kphA:
17.0		 4qtuB-1kphA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
GLY A  74
SER A  96
ILE A 136
ALA A 138
 SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-4.2A)
SAH  A1900 (-3.2A)
 0.38A 4qtuD-1kphA:
16.8		 4qtuD-1kphA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
GLY A  74
GLY A  76
LEU A  95
ALA A 138
 SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-4.4A)
SAH  A1900 (-3.2A)
 0.96A 4uciA-1kphA:
6.6		 4uciA-1kphA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  72
GLY A  74
GLY A  76
LEU A  95
ALA A 138
 SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-4.4A)
SAH  A1900 (-3.2A)
 0.95A 4uciB-1kphA:
6.6		 4uciB-1kphA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		4 / 7 PHE A 283
LEU A 166
GLU A 140
VAL A 211
 None
None
CO3  A1902 ( 3.6A)
None
 1.02A 4wnvD-1kphA:
0.9		 4wnvD-1kphA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		6 / 12 SER A  34
GLY A  72
GLY A  74
THR A  94
GLN A  99
HIS A 141
 SAH  A1900 ( 3.6A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
SAH  A1900 (-4.0A)
SAH  A1900 (-2.9A)
SAH  A1900 (-4.4A)
 0.72A 5kocB-1kphA:
27.6		 5kocB-1kphA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 12 SER A  34
GLY A  72
GLY A  74
SER A  96
GLN A  99
 SAH  A1900 ( 3.6A)
SAH  A1900 (-3.1A)
SAH  A1900 (-3.2A)
None
SAH  A1900 (-2.9A)
 0.72A 5kpcB-1kphA:
27.8		 5kpcB-1kphA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		5 / 7 LEU A 266
ILE A 278
GLY A 171
LEU A 205
ILE A 199
 None
10A  A1901 ( 4.4A)
None
10A  A1901 (-3.9A)
None
 1.31A 5vkqA-1kphA:
2.4
5vkqB-1kphA:
2.4		 5vkqA-1kphA:
10.16
5vkqB-1kphA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 1kph CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 1
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  16
GLN A  99
THR A  94
LEU A  95
 SAH  A1900 ( 4.2A)
SAH  A1900 (-2.9A)
SAH  A1900 (-4.0A)
SAH  A1900 (-4.4A)
 1.22A 6d8pA-1kphA:
0.0		 6d8pA-1kphA:
17.01