SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kpl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.94A 1c6zA-1kplA:
undetectable		 1c6zA-1kplA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 338
ALA A 312
THR A 343
VAL A 342
LEU A 307
 None
 1.04A 1cbsA-1kplA:
undetectable		 1cbsA-1kplA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 THR A 138
GLY A 134
GLY A 355
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
 0.70A 1d0vA-1kplA:
undetectable		 1d0vA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.91A 1hsgB-1kplA:
undetectable		 1hsgB-1kplA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 8 ARG A 340
ALA A 370
GLY A 393
PRO A 321
ILE A 320
 None
 1.15A 1hshD-1kplA:
undetectable		 1hshD-1kplA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 THR A 138
GLY A 134
GLY A 355
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
 0.73A 1jhaA-1kplA:
undetectable		 1jhaA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.15A 1jhoA-1kplA:
undetectable		 1jhoA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 8 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.16A 1jhqA-1kplA:
undetectable		 1jhqA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.16A 1jhrA-1kplA:
undetectable		 1jhrA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 GLY A  50
GLY A 181
LEU A 158
GLY A  43
 None
 0.76A 1jhvA-1kplA:
undetectable		 1jhvA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 8 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.16A 1jhvA-1kplA:
undetectable		 1jhvA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.13A 1jhyA-1kplA:
undetectable		 1jhyA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.14A 1l4nA-1kplA:
undetectable		 1l4nA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.15A 1l5kA-1kplA:
undetectable		 1l5kA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.15A 1l5lA-1kplA:
undetectable		 1l5lA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 134
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.14A 1l5mA-1kplA:
undetectable		 1l5mA-1kplA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 THR A 180
LEU A 177
VAL A 162
 None
 0.61A 1mz9E-1kplA:
undetectable		 1mz9E-1kplA:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 12 THR A 452
ILE A 109
GLY A 108
GLY A 106
ILE A 448
ALA A 104
 None
 1.32A 1nv8B-1kplA:
undetectable		 1nv8B-1kplA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE A 317
ASN A 318
ARG A 147
GLY A 315
 None
 0.93A 1oniA-1kplA:
0.0
1oniB-1kplA:
0.0		 1oniA-1kplA:
13.71
1oniB-1kplA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 6 PHE A 317
ASN A 318
ARG A 147
GLY A 315
 None
 1.00A 1oniD-1kplA:
0.0
1oniF-1kplA:
0.0		 1oniD-1kplA:
13.71
1oniF-1kplA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 GLY A 315
PHE A 317
ASN A 318
ARG A 147
 None
 0.97A 1oniG-1kplA:
0.0
1oniI-1kplA:
0.0		 1oniG-1kplA:
13.71
1oniI-1kplA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 12 THR A 452
ILE A 109
GLY A 108
GLY A 106
ILE A 448
ALA A 104
 None
 1.37A 1sg9B-1kplA:
undetectable		 1sg9B-1kplA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 12 THR A 452
ILE A 109
GLY A 108
GLY A 106
ILE A 448
ALA A 104
 None
 1.41A 1vq1B-1kplA:
undetectable		 1vq1B-1kplA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 ALA A 370
PHE A 371
ALA A 375
LEU A 254
 None
 0.40A 2bxmA-1kplA:
1.0		 2bxmA-1kplA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 10 ALA A 370
PHE A 371
ALA A 375
LEU A 254
LEU A 334
 None
 1.09A 2bxqA-1kplA:
0.0		 2bxqA-1kplA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 338
ALA A 312
THR A 343
VAL A 342
LEU A 307
 None
 1.05A 2fr3A-1kplA:
undetectable		 2fr3A-1kplA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 303
GLY A 306
ALA A 141
ALA A  87
ALA A  82
 None
 0.96A 2gluB-1kplA:
undetectable		 2gluB-1kplA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 197
ILE A 200
ALA A 183
ALA A  39
ILE A  35
 None
 0.95A 2h79A-1kplA:
0.4		 2h79A-1kplA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 11 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.85A 2r5qB-1kplA:
undetectable		 2r5qB-1kplA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 10 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.85A 2r5qD-1kplA:
undetectable		 2r5qD-1kplA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 11 PRO A 359
MET A 360
MET A 398
GLY A 149
THR A 151
 None
None
None
CL  A 503 ( 3.7A)
None
 1.47A 2uvnB-1kplA:
0.0		 2uvnB-1kplA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 158
GLY A  47
GLY A 185
THR A 180
 None
 0.76A 2wd9A-1kplA:
undetectable		 2wd9A-1kplA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 LEU A 158
GLY A  47
GLY A 185
THR A 180
 None
 0.75A 2wd9B-1kplA:
undetectable		 2wd9B-1kplA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 VAL A  57
GLY A 135
PRO A 150
THR A 151
GLY A  50
 None
 1.13A 3bjwG-1kplA:
0.0		 3bjwG-1kplA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 GLY A 300
GLY A 142
GLY A 303
 None
 0.38A 3bogC-1kplA:
undetectable		 3bogC-1kplA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 4 SER A 225
GLY A  47
GLY A 221
GLY A 181
 None
 0.74A 3bogB-1kplA:
0.0
3bogD-1kplA:
0.0		 3bogB-1kplA:
undetectable
3bogD-1kplA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 345
GLN A 277
THR A 276
LEU A 145
 None
 1.25A 3ce6D-1kplA:
undetectable		 3ce6D-1kplA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.97A 3d1zA-1kplA:
undetectable		 3d1zA-1kplA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.90A 3ekqA-1kplA:
undetectable		 3ekqA-1kplA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 351
GLY A 149
GLY A 108
GLY A 105
PHE A 190
 None
CL  A 503 ( 3.7A)
None
None
None
 0.87A 3eluA-1kplA:
undetectable		 3eluA-1kplA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 351
GLY A 149
GLY A 108
GLY A 105
PHE A 190
 None
CL  A 503 ( 3.7A)
None
None
None
 0.94A 3elwA-1kplA:
undetectable		 3elwA-1kplA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 197
ILE A 200
ALA A 183
ALA A  39
ILE A  35
 None
 0.94A 3gwsX-1kplA:
0.7		 3gwsX-1kplA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 351
GLN A 277
LEU A 274
ARG A 451
ILE A 298
 None
 1.22A 3h52B-1kplA:
undetectable		 3h52B-1kplA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.97A 3k4vD-1kplA:
undetectable		 3k4vD-1kplA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.96A 3nu3A-1kplA:
undetectable		 3nu3A-1kplA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 0.91A 3oxxC-1kplA:
undetectable		 3oxxC-1kplA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.85A 3p97C-1kplA:
undetectable		 3p97C-1kplA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 11 GLY A 196
ALA A 183
VAL A  42
GLY A  43
ILE A 223
 None
 0.83A 3ufnA-1kplA:
undetectable		 3ufnA-1kplA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 TRP A 125
VAL A 130
TRP A 124
 None
 1.47A 3zq8A-1kplA:
undetectable
3zq8B-1kplA:
undetectable		 3zq8A-1kplA:
4.78
3zq8B-1kplA:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.84A 4ctjA-1kplA:
undetectable		 4ctjA-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.86A 4ctjC-1kplA:
undetectable		 4ctjC-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.85A 4ctkC-1kplA:
undetectable		 4ctkC-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 1.01A 4jecB-1kplA:
undetectable		 4jecB-1kplA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 9 THR A 138
GLY A 135
GLY A 355
LEU A 145
GLY A 106
 None
None
CL  A 503 (-3.5A)
None
None
 1.29A 4kqiA-1kplA:
undetectable		 4kqiA-1kplA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 LEU A 444
ILE A 448
ARG A 451
 None
 0.51A 4mk4B-1kplA:
undetectable		 4mk4B-1kplA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 181
ALA A 182
ILE A 109
PRO A 206
ILE A 200
 None
 1.04A 4njvD-1kplA:
undetectable		 4njvD-1kplA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 11 GLY A 105
ALA A 104
ILE A 154
THR A 151
ILE A 109
VAL A 122
 None
 1.29A 4qgiA-1kplA:
undetectable		 4qgiA-1kplA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 358
ASN A 318
GLN A  61
ALA A 313
GLY A 354
 None
 1.13A 4r38B-1kplA:
undetectable		 4r38B-1kplA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 358
ASN A 318
GLN A  61
ALA A 313
GLY A 355
 None
None
None
None
CL  A 503 (-3.5A)
 1.19A 4r38B-1kplA:
undetectable		 4r38B-1kplA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 GLY A 263
ALA A 432
GLY A 266
PRO A 267
 None
 0.86A 4u9uA-1kplA:
undetectable		 4u9uA-1kplA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 GLY A 263
ALA A 432
GLY A 266
PRO A 267
 None
 0.88A 4u9uB-1kplA:
undetectable		 4u9uB-1kplA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 4 ALA A  39
VAL A 222
GLY A 185
THR A  46
 None
 0.91A 4ubeA-1kplA:
undetectable		 4ubeA-1kplA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 4 ALA A 189
VAL A 152
GLY A 181
THR A  46
 None
 1.03A 4ubeA-1kplA:
undetectable		 4ubeA-1kplA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 8 ALA A 184
VAL A  42
GLY A 185
ALA A 188
GLY A  47
 None
 1.28A 4zjzB-1kplA:
undetectable		 4zjzB-1kplA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A 350
TYR A  94
GLY A 351
GLY A 354
 None
 0.80A 5albL-1kplA:
undetectable		 5albL-1kplA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A 350
TYR A  94
GLY A 351
GLY A 354
 None
 0.74A 5alcL-1kplA:
undetectable		 5alcL-1kplA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 188
GLY A 155
GLY A 185
GLY A 149
LEU A 158
 None
None
None
CL  A 503 ( 3.7A)
None
 1.14A 5c0oE-1kplA:
undetectable		 5c0oE-1kplA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 362
GLY A 314
GLY A 316
GLY A 146
LEU A 145
 None
 0.75A 5c0oE-1kplA:
undetectable		 5c0oE-1kplA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 12 ALA A 362
GLY A 314
GLY A 316
GLY A 146
LEU A 145
ALA A 311
 None
 1.41A 5c0oG-1kplA:
undetectable		 5c0oG-1kplA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 GLY A 185
SER A 225
GLY A  47
ALA A 189
 None
 0.96A 5e26A-1kplA:
undetectable
5e26B-1kplA:
undetectable		 5e26A-1kplA:
21.65
5e26B-1kplA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 12 SER A 225
GLY A 221
GLY A 156
GLY A  43
VAL A 122
ILE A 112
 None
 1.36A 5ec8A-1kplA:
undetectable		 5ec8A-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.88A 5ec8C-1kplA:
undetectable		 5ec8C-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.84A 5ehiA-1kplA:
undetectable		 5ehiA-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.86A 5ehiC-1kplA:
undetectable		 5ehiC-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.86A 5eiwA-1kplA:
undetectable		 5eiwA-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 196
GLY A 408
GLU A 203
VAL A 222
ILE A 197
 None
 0.83A 5ekxB-1kplA:
undetectable		 5ekxB-1kplA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 352
GLY A 105
GLY A 355
SER A 107
SER A 350
 None
None
CL  A 503 (-3.5A)
CL  A 503 (-3.1A)
None
 1.12A 5gwxA-1kplA:
undetectable		 5gwxA-1kplA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 423
ILE A 391
GLY A 387
LEU A 252
ALA A 247
 None
None
None
OCT  A 502 ( 4.9A)
None
 1.04A 5h5fA-1kplA:
undetectable		 5h5fA-1kplA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 GLY A 315
GLY A 314
GLN A  61
 None
 0.45A 5imsA-1kplA:
undetectable		 5imsA-1kplA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 105
ALA A 104
ILE A 154
GLY A 149
ILE A 109
VAL A 122
 None
None
None
CL  A 503 ( 3.7A)
None
None
 1.50A 5kqxA-1kplA:
undetectable		 5kqxA-1kplA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 366
GLY A 368
GLY A 393
ALA A 324
 None
 0.67A 5o96C-1kplA:
undetectable		 5o96C-1kplA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 7 GLY A 331
LEU A 332
ILE A 336
LEU A 366
ILE A 322
 None
 1.27A 5vkqA-1kplA:
undetectable
5vkqB-1kplA:
undetectable		 5vkqA-1kplA:
14.72
5vkqB-1kplA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 8 GLY A 331
LEU A 332
ILE A 336
LEU A 366
ILE A 322
 None
 1.24A 5vkqB-1kplA:
undetectable
5vkqC-1kplA:
undetectable		 5vkqB-1kplA:
14.72
5vkqC-1kplA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 THR A 180
GLY A 181
ALA A 184
GLY A 159
 None
 0.57A 5vw9A-1kplA:
undetectable		 5vw9A-1kplA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 10 MET A 224
SER A 225
ILE A 200
SER A 187
GLY A 196
 None
 1.04A 5weoA-1kplA:
1.0
5weoD-1kplA:
undetectable		 5weoA-1kplA:
19.03
5weoD-1kplA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 185
PRO A 193
ALA A 192
THR A  46
VAL A  42
 None
 1.35A 5x6yA-1kplA:
undetectable		 5x6yA-1kplA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 158
THR A  46
THR A 180
GLY A  43
 None
 1.21A 6gtqA-1kplA:
undetectable		 6gtqA-1kplA:
17.23