SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2Y_B_EF2B151_1 (CEREBLON ISOFORM 4)	1kq8	HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1 (Rattus norvegicus)	4 / 7	PRO A 38 PHE A 39 TRP A 47 TYR A 8	None	1.48A	4v2yB-1kq8A: undetectable	4v2yB-1kq8A: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2Z_B_Y70B151_1 (CEREBLON ISOFORM 4)	1kq8	HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1 (Rattus norvegicus)	4 / 8	PRO A 38 PHE A 39 TRP A 47 TYR A 8	None	1.47A	4v2zB-1kq8A: undetectable	4v2zB-1kq8A: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AMJ_B_EF2B151_1 (CEREBLON ISOFORM 4)	1kq8	HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1 (Rattus norvegicus)	4 / 7	PRO A 38 PHE A 39 TRP A 47 TYR A 8	None	1.49A	5amjB-1kq8A: undetectable	5amjB-1kq8A: 22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OH3_B_9V2B202_0 (CEREBLON ISOFORM 4)	1kq8	HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1 (Rattus norvegicus)	4 / 7	PRO A 38 PHE A 39 TRP A 47 TYR A 8	None	1.46A	5oh3B-1kq8A: undetectable	5oh3B-1kq8A: 22.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4V2Y_B_EF2B151_1","CEREBLON ISOFORM 4","1kq8","HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1","Rattus norvegicus",4,"PRO A  38;PHE A  39;TRP A  47;TYR A   8","None","1.48A","4v2yB-1kq8A:undetectable","4v2yB-1kq8A:22.38"],["4V2Z_B_Y70B151_1","CEREBLON ISOFORM 4","1kq8","HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1","Rattus norvegicus",4,"PRO A  38;PHE A  39;TRP A  47;TYR A   8","None","1.47A","4v2zB-1kq8A:undetectable","4v2zB-1kq8A:22.38"],["5AMJ_B_EF2B151_1","CEREBLON ISOFORM 4","1kq8","HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1","Rattus norvegicus",4,"PRO A  38;PHE A  39;TRP A  47;TYR A   8","None","1.49A","5amjB-1kq8A:undetectable","5amjB-1kq8A:22.38"],["5OH3_B_9V2B202_0","CEREBLON ISOFORM 4","1kq8","HEPATOCYTE NUCLEAR FACTOR 3 FORKHEAD HOMOLOG 1","Rattus norvegicus",4,"PRO A  38;PHE A  39;TRP A  47;TYR A   8","None","1.46A","5oh3B-1kq8A:undetectable","5oh3B-1kq8A:22.38"]]