SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kri'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1kri VP4
(Rotavirus
A) 		4 / 7 ALA A 104
ILE A 128
TYR A 152
ILE A 141
 None
 0.94A 1oniD-1kriA:
undetectable
1oniF-1kriA:
undetectable		 1oniD-1kriA:
20.97
1oniF-1kriA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 1kri VP4
(Rotavirus
A) 		4 / 7 THR A 215
TYR A 219
ASN A 222
LEU A 164
 None
 0.94A 1qzrA-1kriA:
0.4		 1qzrA-1kriA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 1kri VP4
(Rotavirus
A) 		4 / 7 THR A 215
TYR A 219
ASN A 222
LEU A 164
 None
 1.03A 1qzrB-1kriA:
0.4		 1qzrB-1kriA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1kri VP4
(Rotavirus
A) 		5 / 11 SER A 160
PHE A 205
LEU A 107
THR A 105
ALA A 104
 None
 1.44A 4dx7A-1kriA:
undetectable		 4dx7A-1kriA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1kri VP4
(Rotavirus
A) 		4 / 5 TYR A 206
LEU A  65
TYR A 219
LEU A 224
 None
 1.14A 4em2A-1kriA:
undetectable		 4em2A-1kriA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1kri VP4
(Rotavirus
A) 		4 / 8 GLY A  90
LEU A 107
ILE A 106
ILE A 130
 None
 0.76A 4em2A-1kriA:
undetectable		 4em2A-1kriA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1kri VP4
(Rotavirus
A) 		5 / 11 LEU A 164
ALA A  85
PRO A  86
THR A 105
ASP A 142
 None
 1.17A 4uuuB-1kriA:
undetectable		 4uuuB-1kriA:
17.11