SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1krm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		11 / 12 HIS A  12
HIS A  14
PHE A  58
PHE A  62
MET A 152
ALA A 180
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 ZN  A 501 ( 3.3A)
PRH  A 401 ( 3.0A)
None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.53A 1a4lA-1krmA:
58.2		 1a4lA-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  14
ASP A  16
PHE A  58
PHE A  62
MET A 152
ALA A 180
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.67A 1a4lA-1krmA:
58.2		 1a4lA-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
PHE A  62
MET A 152
ALA A 180
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-3.5A)
 1.18A 1a4lA-1krmA:
58.2		 1a4lA-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 PHE A  58
PHE A  62
MET A 152
ALA A 180
HIS A  12
ASP A 293
 None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.3A)
PRH  A 401 (-3.5A)
 1.38A 1a4lA-1krmA:
58.2		 1a4lA-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		12 / 12 HIS A  14
ASP A  16
PHE A  58
LEU A  59
PHE A  62
MET A 152
ALA A 180
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.60A 1a4lB-1krmA:
58.2		 1a4lB-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 PHE A  58
LEU A  59
HIS A 211
ASP A 292
ASP A 293
 None
PRH  A 401 (-4.5A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.30A 1a4lB-1krmA:
58.2		 1a4lB-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 PHE A  58
LEU A  59
PHE A  62
MET A 152
HIS A  12
ASP A 293
 None
PRH  A 401 (-4.5A)
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
ZN  A 501 ( 3.3A)
PRH  A 401 (-3.5A)
 1.33A 1a4lB-1krmA:
58.2		 1a4lB-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 5 HIS A  12
LEU A  55
SER A 100
LEU A 103
GLY A 181
 ZN  A 501 ( 3.3A)
None
None
PRH  A 401 (-4.4A)
PRH  A 401 (-4.0A)
 0.54A 1a4lB-1krmA:
58.2		 1a4lB-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		11 / 12 HIS A  12
HIS A  14
PHE A  58
PHE A  62
MET A 152
ALA A 180
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 ZN  A 501 ( 3.3A)
PRH  A 401 ( 3.0A)
None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.49A 1a4lC-1krmA:
58.0		 1a4lC-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 HIS A  12
HIS A  14
PHE A 297
HIS A 235
ASP A 292
ASP A 293
 ZN  A 501 ( 3.3A)
PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.46A 1a4lC-1krmA:
58.0		 1a4lC-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		10 / 12 HIS A  14
ASP A  16
PHE A  58
PHE A  62
MET A 152
ALA A 180
HIS A 211
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.65A 1a4lC-1krmA:
58.0		 1a4lC-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
PHE A  62
MET A 152
ALA A 180
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-3.5A)
 1.14A 1a4lC-1krmA:
58.0		 1a4lC-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
PHE A 297
PHE A  58
HIS A  12
ASP A 293
 PRH  A 401 ( 3.0A)
None
None
ZN  A 501 ( 3.3A)
PRH  A 401 (-3.5A)
 1.27A 1a4lC-1krmA:
58.0		 1a4lC-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 5 LEU A  55
LEU A  59
SER A 100
LEU A 103
GLY A 181
 None
PRH  A 401 (-4.5A)
None
PRH  A 401 (-4.4A)
PRH  A 401 (-4.0A)
 0.32A 1a4lC-1krmA:
58.0		 1a4lC-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		11 / 12 HIS A  14
ASP A  16
PHE A  58
PHE A  62
MET A 152
ALA A 180
GLY A 181
HIS A 211
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.60A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
ASP A 293
PHE A  58
ALA A 180
GLY A 181
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.5A)
None
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
 1.46A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
PHE A  58
ALA A 180
GLY A 181
ASP A 292
 PRH  A 401 ( 3.0A)
None
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
 0.96A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		11 / 12 HIS A  14
PHE A  58
PHE A  62
MET A 152
ALA A 180
GLY A 181
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.44A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 HIS A  14
PHE A  62
MET A 152
ALA A 180
GLY A 181
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
PRH  A 401 (-3.5A)
 1.29A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 HIS A  14
PHE A  62
MET A 152
ALA A 180
GLY A 181
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
PRH  A 401 (-3.5A)
 1.43A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		7 / 12 PHE A  58
PHE A  62
MET A 152
ALA A 180
GLY A 181
HIS A  12
ASP A 293
 None
PRH  A 401 ( 4.4A)
PRH  A 401 (-4.1A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.3A)
PRH  A 401 (-3.5A)
 1.33A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 4 HIS A  12
LEU A  55
LEU A  59
LEU A 103
 ZN  A 501 ( 3.3A)
None
PRH  A 401 (-4.5A)
PRH  A 401 (-4.4A)
 0.54A 1a4lD-1krmA:
58.3		 1a4lD-1krmA:
84.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		3 / 3 THR A 266
PRO A  56
THR A  54
 None
 0.90A 1dscC-1krmA:
undetectable		 1dscC-1krmA:
4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 THR A 230
LEU A 249
GLY A 236
GLY A 234
ALA A 212
 None
 1.01A 1httC-1krmA:
undetectable		 1httC-1krmA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 THR A 230
LEU A 249
GLY A 236
GLY A 234
ALA A 212
 None
 1.02A 1httD-1krmA:
undetectable		 1httD-1krmA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 LEU A 344
TYR A  94
GLY A  91
TYR A 348
 None
 1.06A 1jlfA-1krmA:
0.8
1jlfB-1krmA:
0.6		 1jlfA-1krmA:
21.96
1jlfB-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 SER A 262
PHE A  58
LEU A  55
VAL A 221
HIS A 211
 None
None
None
None
ZN  A 501 ( 3.4A)
 1.19A 1q23H-1krmA:
undetectable
1q23I-1krmA:
0.0		 1q23H-1krmA:
18.82
1q23I-1krmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 LEU A 344
TYR A  94
GLY A  91
TYR A 348
 None
 1.03A 1s1xA-1krmA:
undetectable		 1s1xA-1krmA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOF_A_PNNA1312_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 11 HIS A  14
ASP A 178
THR A 209
HIS A 211
SER A 288
 PRH  A 401 ( 3.0A)
None
None
ZN  A 501 ( 3.4A)
None
 1.13A 1uofA-1krmA:
undetectable		 1uofA-1krmA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 11 LEU A 103
HIS A  12
HIS A 211
ASP A 292
ASP A 293
 PRH  A 401 (-4.4A)
ZN  A 501 ( 3.3A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.21A 1zz1A-1krmA:
undetectable		 1zz1A-1krmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 LEU A 103
HIS A  12
HIS A 211
ASP A 292
ASP A 293
 PRH  A 401 (-4.4A)
ZN  A 501 ( 3.3A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.21A 1zz1B-1krmA:
undetectable
1zz1C-1krmA:
undetectable		 1zz1B-1krmA:
23.04
1zz1C-1krmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 7 GLU A  10
ALA A 327
ASN A 323
ALA A 326
 None
 0.95A 2ejfA-1krmA:
undetectable		 2ejfA-1krmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 THR A 266
ASP A 304
THR A 303
ASP A  90
 None
 1.05A 2okcB-1krmA:
undetectable		 2okcB-1krmA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		7 / 12 HIS A  14
ASP A  16
GLY A 181
HIS A 211
HIS A 235
SER A 262
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
None
PRH  A 401 (-3.5A)
 0.80A 2pgfA-1krmA:
40.5		 2pgfA-1krmA:
28.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  14
PHE A  58
GLY A 181
HIS A 211
GLU A 214
HIS A 235
SER A 262
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
None
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.48A 2pgfA-1krmA:
40.5		 2pgfA-1krmA:
28.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		7 / 12 HIS A  12
HIS A  14
ASP A  16
GLY A 181
HIS A 211
HIS A 235
ASP A 293
 ZN  A 501 ( 3.3A)
PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
PRH  A 401 (-3.5A)
 0.76A 2pgrA-1krmA:
40.5		 2pgrA-1krmA:
28.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  12
HIS A  14
PHE A  58
GLY A 181
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 ZN  A 501 ( 3.3A)
PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.46A 2pgrA-1krmA:
40.5		 2pgrA-1krmA:
28.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		3 / 3 ARG A 248
THR A 230
VAL A 225
 None
 0.98A 2qakA-1krmA:
0.0		 2qakA-1krmA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 HIS A 211
ASP A 178
ILE A 148
HIS A  14
 ZN  A 501 ( 3.4A)
None
None
PRH  A 401 ( 3.0A)
 0.91A 2xadA-1krmA:
undetectable		 2xadA-1krmA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 HIS A 211
ASP A 178
ILE A 148
HIS A  14
 ZN  A 501 ( 3.4A)
None
None
PRH  A 401 ( 3.0A)
 0.94A 2xadB-1krmA:
undetectable		 2xadB-1krmA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 HIS A 211
ASP A 178
ILE A 148
HIS A  14
 ZN  A 501 ( 3.4A)
None
None
PRH  A 401 ( 3.0A)
 0.95A 2xadC-1krmA:
undetectable		 2xadC-1krmA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 HIS A 211
ASP A 178
ILE A 148
HIS A  14
 ZN  A 501 ( 3.4A)
None
None
PRH  A 401 ( 3.0A)
 0.90A 2xadD-1krmA:
undetectable		 2xadD-1krmA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 7 GLU A  10
ALA A 327
ASN A 323
ALA A 326
 None
 0.93A 2zgwA-1krmA:
undetectable		 2zgwA-1krmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 GLU A  10
ALA A 327
ASN A 323
ALA A 326
 None
 0.95A 2zgwB-1krmA:
undetectable		 2zgwB-1krmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 ALA A 276
TYR A 246
ILE A 258
HIS A 255
 None
 1.03A 2zmaA-1krmA:
undetectable		 2zmaA-1krmA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 5 HIS A  12
HIS A 211
ASP A 292
ASP A 293
 ZN  A 501 ( 3.3A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.16A 3c0zA-1krmA:
undetectable		 3c0zA-1krmA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 HIS A  12
HIS A 211
ASP A 292
ASP A 293
 ZN  A 501 ( 3.3A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.20A 3c0zC-1krmA:
undetectable		 3c0zC-1krmA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 4 GLY A 133
TYR A  81
GLY A 137
ASP A 140
 None
 1.34A 3kl3A-1krmA:
5.2		 3kl3A-1krmA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 HIS A 235
HIS A 211
HIS A  12
ASP A 293
 PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
ZN  A 501 ( 3.3A)
PRH  A 401 (-3.5A)
 0.80A 3nvcA-1krmA:
undetectable		 3nvcA-1krmA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 GLU A  10
ASP A 304
TYR A 305
ASP A 302
 None
 1.09A 3pocB-1krmA:
2.2		 3pocB-1krmA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 LEU A 233
ALA A 276
LEU A 240
THR A 239
 None
 0.93A 3rozA-1krmA:
undetectable		 3rozA-1krmA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		3 / 3 HIS A 211
HIS A  12
HIS A 235
 ZN  A 501 ( 3.4A)
ZN  A 501 ( 3.3A)
PRH  A 401 (-4.0A)
 0.76A 3s3dA-1krmA:
undetectable		 3s3dA-1krmA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		3 / 3 HIS A 211
SER A 288
GLU A 257
 ZN  A 501 ( 3.4A)
None
None
 0.93A 3s8pA-1krmA:
0.0		 3s8pA-1krmA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 LEU A  59
GLY A 267
GLU A 214
ASP A 293
SER A 262
 PRH  A 401 (-4.5A)
None
PRH  A 401 (-2.5A)
PRH  A 401 (-3.5A)
None
 1.27A 3tbgA-1krmA:
0.0		 3tbgA-1krmA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 LEU A  59
GLY A 267
GLU A 214
ASP A 293
SER A 262
 PRH  A 401 (-4.5A)
None
PRH  A 401 (-2.5A)
PRH  A 401 (-3.5A)
None
 1.30A 3tbgC-1krmA:
0.0		 3tbgC-1krmA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		7 / 12 LEU A  55
LEU A  59
HIS A 211
GLU A 214
GLU A 183
HIS A 235
ASP A 292
 None
PRH  A 401 (-4.5A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
None
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
 0.95A 4aqlA-1krmA:
20.7		 4aqlA-1krmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		7 / 12 LEU A  55
LEU A  59
HIS A 211
GLU A 214
HIS A 235
SER A 262
ASP A 292
 None
PRH  A 401 (-4.5A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
None
PRH  A 401 ( 2.5A)
 0.79A 4aqlA-1krmA:
20.7		 4aqlA-1krmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 GLY A 181
ASP A 293
HIS A  14
ASP A 292
HIS A  12
 PRH  A 401 (-4.0A)
PRH  A 401 (-3.5A)
PRH  A 401 ( 3.0A)
PRH  A 401 ( 2.5A)
ZN  A 501 ( 3.3A)
 0.90A 4bz6C-1krmA:
undetectable		 4bz6C-1krmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 4 HIS A  12
HIS A  14
HIS A 235
HIS A 211
 ZN  A 501 ( 3.3A)
PRH  A 401 ( 3.0A)
PRH  A 401 (-4.0A)
ZN  A 501 ( 3.4A)
 1.04A 4ef3A-1krmA:
undetectable		 4ef3A-1krmA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 4 PRO A  36
LEU A  35
ILE A  33
ARG A  31
 None
 1.19A 4f4dA-1krmA:
0.0		 4f4dA-1krmA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		3 / 3 LEU A 301
ASP A 304
TYR A 305
 None
 0.45A 4qc6B-1krmA:
0.0		 4qc6B-1krmA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 5 TYR A 237
SER A 288
ASP A 292
ASP A  16
 None
None
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.4A)
 1.16A 4qtuB-1krmA:
undetectable		 4qtuB-1krmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 6 TYR A 287
GLU A 317
THR A 315
LEU A 322
 None
 1.42A 4qzuC-1krmA:
undetectable		 4qzuC-1krmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
HIS A 211
HIS A 235
ASP A 292
 PRH  A 401 ( 3.0A)
None
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
 0.57A 4r88A-1krmA:
22.1		 4r88A-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 LEU A  59
HIS A  14
HIS A 211
LEU A  55
SER A 262
 PRH  A 401 (-4.5A)
PRH  A 401 ( 3.0A)
ZN  A 501 ( 3.4A)
None
None
 1.44A 4r88A-1krmA:
22.1		 4r88A-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
HIS A 211
GLU A 214
ASP A 292
 PRH  A 401 ( 3.0A)
None
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 ( 2.5A)
 0.54A 4r88B-1krmA:
22.1		 4r88B-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
HIS A 211
GLU A 214
ASP A 292
 PRH  A 401 ( 3.0A)
None
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 ( 2.5A)
 0.57A 4r88C-1krmA:
22.1		 4r88C-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
HIS A 211
GLU A 214
ASP A 292
 PRH  A 401 ( 3.0A)
None
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 ( 2.5A)
 0.52A 4r88D-1krmA:
19.5		 4r88D-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
HIS A 211
GLU A 214
ASP A 292
 PRH  A 401 ( 3.0A)
None
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 ( 2.5A)
 0.52A 4r88E-1krmA:
22.2		 4r88E-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
HIS A 211
GLU A 214
ASP A 292
 PRH  A 401 ( 3.0A)
None
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 ( 2.5A)
 0.54A 4r88F-1krmA:
22.2		 4r88F-1krmA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 5 LEU A 104
ALA A  75
THR A  23
ILE A  24
 None
 0.93A 4xe3B-1krmA:
undetectable		 4xe3B-1krmA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 7 GLU A  96
ARG A 232
TYR A  94
ALA A 326
 None
 0.91A 4zz8A-1krmA:
0.0		 4zz8A-1krmA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		3 / 3 ASN A 290
SER A 288
ARG A 232
 None
 0.94A 5b2qA-1krmA:
1.0		 5b2qA-1krmA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 ASP A 293
ASP A 292
GLU A 257
ASP A 178
 PRH  A 401 (-3.5A)
PRH  A 401 ( 2.5A)
None
None
 0.95A 5cfsA-1krmA:
0.0		 5cfsA-1krmA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 PHE A 331
ALA A 176
GLY A 234
LEU A  11
ILE A 148
 None
 0.99A 5m24A-1krmA:
undetectable		 5m24A-1krmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 VAL A 220
GLY A 234
LEU A 233
THR A 209
 None
 0.87A 5sxqA-1krmA:
0.0		 5sxqA-1krmA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 VAL A 220
GLY A 234
LEU A 233
THR A 209
 None
 0.79A 5sxtA-1krmA:
0.0		 5sxtA-1krmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		4 / 8 VAL A 220
GLY A 234
LEU A 233
THR A 209
 None
 0.89A 5syjB-1krmA:
0.0		 5syjB-1krmA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  12
ASP A 178
LEU A  55
HIS A 235
ASP A 292
 ZN  A 501 ( 3.3A)
None
None
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
 1.30A 6n91A-1krmA:
43.8		 6n91A-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  14
ASP A  16
LEU A  55
LEU A  59
ALA A 180
HIS A 211
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.75A 6n91A-1krmA:
43.8		 6n91A-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
LEU A  59
ALA A 180
ASP A 293
 PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-3.5A)
 1.29A 6n91A-1krmA:
43.8		 6n91A-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  14
LEU A  55
LEU A  59
ALA A 180
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.55A 6n91A-1krmA:
43.8		 6n91A-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 HIS A  14
LEU A  59
ALA A 180
HIS A 211
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.20A 6n91A-1krmA:
43.8		 6n91A-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  12
ASP A 178
LEU A  55
HIS A 235
ASP A 292
 ZN  A 501 ( 3.3A)
None
None
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
 1.28A 6n91B-1krmA:
43.8		 6n91B-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  14
ASP A  16
LEU A  55
LEU A  59
ALA A 180
HIS A 211
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-3.4A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.77A 6n91B-1krmA:
43.8		 6n91B-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		5 / 12 HIS A  14
LEU A  55
LEU A  59
ALA A 180
ASP A 293
 PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
PRH  A 401 (-3.5A)
 1.27A 6n91B-1krmA:
43.8		 6n91B-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		9 / 12 HIS A  14
LEU A  55
LEU A  59
ALA A 180
HIS A 211
GLU A 214
HIS A 235
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
None
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 (-2.5A)
PRH  A 401 (-4.0A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 0.59A 6n91B-1krmA:
43.8		 6n91B-1krmA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 1krm ADENOSINE DEAMINASE
(Bos
taurus) 		6 / 12 HIS A  14
LEU A  59
ALA A 180
HIS A 211
ASP A 292
ASP A 293
 PRH  A 401 ( 3.0A)
PRH  A 401 (-4.5A)
PRH  A 401 ( 3.8A)
ZN  A 501 ( 3.4A)
PRH  A 401 ( 2.5A)
PRH  A 401 (-3.5A)
 1.17A 6n91B-1krmA:
43.8		 6n91B-1krmA:
12.36