SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1krq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1krq FERRITIN
(Campylobacter
jejuni) 		4 / 8 LEU A  83
ILE A 158
ILE A 141
ILE A 137
 None
 0.69A 2bu8A-1krqA:
3.7		 2bu8A-1krqA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1krq FERRITIN
(Campylobacter
jejuni) 		5 / 10 ILE A 161
ALA A  39
LEU A  83
ILE A 137
ILE A 144
 None
 1.17A 2w9sC-1krqA:
undetectable		 2w9sC-1krqA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1krq FERRITIN
(Campylobacter
jejuni) 		5 / 12 ILE A 137
GLY A 136
ASP A 139
PHE A  87
ALA A 132
 None
 0.83A 3jb1A-1krqA:
undetectable		 3jb1A-1krqA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1krq FERRITIN
(Campylobacter
jejuni) 		5 / 12 LEU A 163
ASP A 155
GLY A  38
ALA A  41
ALA A  45
 None
 1.00A 3p5nA-1krqA:
2.1		 3p5nA-1krqA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 1krq FERRITIN
(Campylobacter
jejuni) 		5 / 12 LEU A 163
ASP A 155
GLY A  38
ALA A  41
ALA A  45
 None
 1.01A 3p5nB-1krqA:
2.2		 3p5nB-1krqA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1krq FERRITIN
(Campylobacter
jejuni) 		5 / 10 ALA A  39
ILE A 137
VAL A 138
ALA A 154
ILE A 141
 None
 1.06A 4lbgA-1krqA:
undetectable		 4lbgA-1krqA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1krq FERRITIN
(Campylobacter
jejuni) 		5 / 9 ALA A  39
ILE A 137
VAL A 138
ALA A 154
ILE A 141
 None
 1.10A 4lbgB-1krqA:
undetectable		 4lbgB-1krqA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1krq FERRITIN
(Campylobacter
jejuni) 		4 / 6 LEU A  70
GLU A  69
ASN A  11
ILE A  14
 None
 0.95A 4ww7A-1krqA:
undetectable		 4ww7A-1krqA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1krq FERRITIN
(Campylobacter
jejuni) 		3 / 3 LEU A  57
ASN A 118
LEU A   2
 None
 0.64A 6exiA-1krqA:
undetectable		 6exiA-1krqA:
18.67