SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1krt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1krt LYSYL-TRNA
SYNTHETASE (PRODUCT
OF LYSS GENE)
(Escherichia
coli) 		4 / 5 ASP A 120
LEU A 145
LEU A 122
LEU A 146
 None
 1.08A 1np1A-1krtA:
0.0		 1np1A-1krtA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1krt LYSYL-TRNA
SYNTHETASE (PRODUCT
OF LYSS GENE)
(Escherichia
coli) 		4 / 8 SER A  46
ILE A 138
LEU A 128
GLY A 126
 None
 0.73A 3dcjB-1krtA:
undetectable		 3dcjB-1krtA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1krt LYSYL-TRNA
SYNTHETASE (PRODUCT
OF LYSS GENE)
(Escherichia
coli) 		5 / 10 ILE A 138
ILE A  95
GLY A  92
LEU A 122
ARG A  73
 None
 1.13A 3elzC-1krtA:
0.0		 3elzC-1krtA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		 1krt LYSYL-TRNA
SYNTHETASE (PRODUCT
OF LYSS GENE)
(Escherichia
coli) 		5 / 9 ILE A 138
PHE A 113
LEU A  97
LEU A 122
ASP A  90
 None
 1.49A 4qopA-1krtA:
undetectable		 4qopA-1krtA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		 1krt LYSYL-TRNA
SYNTHETASE (PRODUCT
OF LYSS GENE)
(Escherichia
coli) 		5 / 9 ILE A 138
PHE A 113
LEU A  97
LEU A 122
ASP A  90
 None
 1.49A 4qopB-1krtA:
undetectable		 4qopB-1krtA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1krt LYSYL-TRNA
SYNTHETASE (PRODUCT
OF LYSS GENE)
(Escherichia
coli) 		4 / 8 LEU A  97
VAL A  86
ALA A 124
LEU A 143
 None
 0.85A 4qrcA-1krtA:
undetectable		 4qrcA-1krtA:
19.06