SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		3 / 3 GLU A 120
HIS A 118
HIS A 119
 None
 0.69A 1oe2A-1kruA:
0.0		 1oe2A-1kruA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 PHE A  55
HIS A  77
ILE A  90
THR A  97
VAL A  64
 None
 1.38A 2gl0B-1kruA:
0.0
2gl0C-1kruA:
0.0		 2gl0B-1kruA:
23.01
2gl0C-1kruA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A  55
HIS A  77
ILE A  90
THR A  97
VAL A  64
 None
 1.45A 2gl0D-1kruA:
undetectable
2gl0E-1kruA:
0.0		 2gl0D-1kruA:
23.01
2gl0E-1kruA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 ILE A  90
THR A  97
VAL A  64
PHE A  55
HIS A  77
 None
 1.45A 2gl0D-1kruA:
0.0
2gl0F-1kruA:
0.0		 2gl0D-1kruA:
23.01
2gl0F-1kruA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 LEU A 110
VAL A 108
ILE A 104
ILE A 134
 None
 0.79A 2piwA-1kruA:
undetectable		 2piwA-1kruA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 PHE A  55
LEU A  88
PHE A  82
ALA A  62
 None
 0.95A 3t3zA-1kruA:
undetectable		 3t3zA-1kruA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 PHE A  55
LEU A  88
PHE A  82
ALA A  62
 None
 0.99A 3t3zB-1kruA:
undetectable		 3t3zB-1kruA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 6 PHE A  55
LEU A  88
PHE A  82
ALA A  62
 None
 1.00A 3t3zD-1kruA:
undetectable		 3t3zD-1kruA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 12 VAL A 138
ILE A 146
VAL A 164
VAL A 181
ALA A 174
 None
 1.27A 4m11C-1kruA:
undetectable		 4m11C-1kruA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		4 / 7 ASP A 100
ARG A  80
GLY A  59
GLU A  60
 None
 1.01A 5btfA-1kruA:
0.0
5btfC-1kruA:
0.0
5btfD-1kruA:
undetectable		 5btfA-1kruA:
17.30
5btfC-1kruA:
17.30
5btfD-1kruA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 10 LEU A  88
ILE A  51
PHE A  36
ILE A  78
ILE A  76
 None
 1.11A 6ebpD-1kruA:
undetectable		 6ebpD-1kruA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A  88
ILE A  51
PHE A  36
ILE A  78
ILE A  76
 None
 1.06A 6gp2A-1kruA:
undetectable		 6gp2A-1kruA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kru GALACTOSIDE
O-ACETYLTRANSFERASE
(Escherichia
coli) 		5 / 11 LEU A  88
ILE A  51
PHE A  36
ILE A  78
ILE A  76
 None
 1.07A 6gp2B-1kruA:
undetectable		 6gp2B-1kruA:
14.29