SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ks8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 8 ALA A 225
LEU A 177
LEU A 178
ALA A 181
 None
 0.81A 1e7cA-1ks8A:
undetectable		 1e7cA-1ks8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 6 LEU A 339
GLY A 351
LYS A   1
TYR A   3
 None
 1.14A 1gtiC-1ks8A:
2.1		 1gtiC-1ks8A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 LEU A 339
GLY A 351
LYS A   1
TYR A   3
 None
 1.14A 1gtiF-1ks8A:
2.1		 1gtiF-1ks8A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 7 VAL A 260
LEU A 263
TYR A 273
ALA A 235
 None
 0.71A 1pthA-1ks8A:
0.0		 1pthA-1ks8A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 7 VAL A 260
LEU A 263
TYR A 273
ALA A 235
 None
 0.70A 1pthB-1ks8A:
0.0		 1pthB-1ks8A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 8 VAL A  59
ARG A 305
GLU A 412
ASP A  57
 None
None
None
SO4  A 450 ( 4.9A)
 1.04A 1s3zA-1ks8A:
undetectable
1s3zB-1ks8A:
undetectable		 1s3zA-1ks8A:
14.75
1s3zB-1ks8A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 VAL A 260
GLY A 259
VAL A 257
TRP A 253
 None
 1.17A 1tkqB-1ks8A:
undetectable		 1tkqB-1ks8A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		3 / 3 ASP A 123
ARG A 361
ASP A  54
 None
SO4  A 450 (-2.9A)
None
 0.97A 1vptA-1ks8A:
undetectable		 1vptA-1ks8A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		3 / 3 GLN A  19
HIS A 360
ARG A 361
 None
None
SO4  A 450 (-2.9A)
 0.77A 1zlqA-1ks8A:
undetectable		 1zlqA-1ks8A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 ILE A 164
ALA A 219
VAL A 260
ARG A 192
PHE A 185
 None
 1.17A 2okcB-1ks8A:
undetectable		 2okcB-1ks8A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		3 / 3 TRP A 247
GLN A 261
TRP A 253
 None
 1.29A 2vqyA-1ks8A:
0.0		 2vqyA-1ks8A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 ALA A 157
ASN A 189
GLU A 154
LEU A 244
THR A  70
 None
 0.96A 3fl9B-1ks8A:
undetectable		 3fl9B-1ks8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 11 ALA A 157
ASN A 189
GLU A 154
LEU A 244
THR A  70
 None
 1.12A 3fl9C-1ks8A:
undetectable		 3fl9C-1ks8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 ALA A 157
ASN A 189
GLU A 154
LEU A 244
THR A  70
 None
 1.03A 3fl9G-1ks8A:
undetectable		 3fl9G-1ks8A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 VAL A 347
GLY A 389
ALA A 419
GLY A 420
LEU A 425
 None
 0.80A 3ku1A-1ks8A:
undetectable		 3ku1A-1ks8A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 VAL A 347
GLY A 389
ALA A 419
GLY A 420
LEU A 425
 None
 0.79A 3ku1C-1ks8A:
undetectable		 3ku1C-1ks8A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 7 TYR A 327
VAL A  71
VAL A 262
ARG A 305
 None
 0.77A 3mssB-1ks8A:
undetectable		 3mssB-1ks8A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 GLY A  62
VAL A  59
ALA A  55
ALA A 414
GLU A 412
 None
 0.93A 3mteB-1ks8A:
undetectable		 3mteB-1ks8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MYU_A_VIBA500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 10 ASP A 299
TRP A 301
TYR A 417
ASP A 416
GLY A 302
 None
 1.45A 3myuA-1ks8A:
0.0		 3myuA-1ks8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 VAL A 260
LEU A 263
TYR A 273
ALA A 235
 None
 0.69A 3n8yB-1ks8A:
0.0		 3n8yB-1ks8A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		3 / 3 TYR A 140
ASP A  43
ASP A 143
 None
 0.89A 3ou7B-1ks8A:
undetectable		 3ou7B-1ks8A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 LEU A 222
TRP A 221
ILE A  77
ASN A 168
 None
 1.40A 4i00A-1ks8A:
undetectable		 4i00A-1ks8A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 8 TRP A  74
LEU A 320
LEU A 322
TYR A 327
ILE A 313
 None
 1.50A 4lzrA-1ks8A:
undetectable		 4lzrA-1ks8A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 ALA A 202
GLY A 115
GLY A  62
PHE A  61
GLY A 118
 None
 1.12A 4n48B-1ks8A:
undetectable		 4n48B-1ks8A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 THR A 415
THR A  68
ASP A 416
TYR A 206
 None
 1.37A 4oltA-1ks8A:
0.0		 4oltA-1ks8A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 THR A 415
THR A  68
ASP A 416
TYR A 206
 None
 1.35A 4oltB-1ks8A:
0.0		 4oltB-1ks8A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 THR A 415
THR A  68
ASP A 416
TYR A 206
 None
 1.35A 4qwpA-1ks8A:
0.0		 4qwpA-1ks8A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 THR A 415
THR A  68
ASP A 416
TYR A 206
 None
 1.34A 4qwpB-1ks8A:
0.0		 4qwpB-1ks8A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 VAL A 260
LEU A 263
TYR A 273
LEU A 222
ALA A 235
 None
 1.07A 4rrwD-1ks8A:
0.0		 4rrwD-1ks8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 VAL A 216
LEU A 251
VAL A 257
GLY A 259
LEU A 264
 None
 1.11A 4rrxA-1ks8A:
0.0		 4rrxA-1ks8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 VAL A 216
LEU A 251
VAL A 257
GLY A 259
LEU A 264
 None
 1.12A 4rrxB-1ks8A:
0.8		 4rrxB-1ks8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 VAL A 260
LEU A 263
TYR A 273
LEU A 222
ALA A 235
 None
 1.07A 4rrzD-1ks8A:
0.0		 4rrzD-1ks8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 ASP A 341
ALA A 424
ALA A 311
TYR A   5
TYR A   3
 None
 1.40A 4u15B-1ks8A:
undetectable		 4u15B-1ks8A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 LEU A 184
LEU A 177
ALA A  99
LYS A  97
ALA A 162
 None
 0.97A 4x20B-1ks8A:
undetectable		 4x20B-1ks8A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 5 ASP A 299
HIS A 306
ARG A 305
ILE A 298
 None
 1.49A 5a06F-1ks8A:
undetectable		 5a06F-1ks8A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		5 / 12 ASP A 341
ALA A 424
ALA A 311
TYR A   5
TYR A   3
 None
 1.42A 5cxvA-1ks8A:
0.0		 5cxvA-1ks8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 7 ASN A 411
VAL A 392
ALA A 390
GLY A 349
 None
 0.91A 5fpdA-1ks8A:
undetectable		 5fpdA-1ks8A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 6 ASP A 213
GLN A 261
GLU A 214
THR A  70
 None
 1.35A 6djzA-1ks8A:
0.0		 6djzA-1ks8A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ks8 ENDO-B-1,4-GLUCANASE
(Nasutitermes
takasagoensis) 		4 / 8 GLN A 245
ALA A 265
VAL A 262
ASP A 240
 None
 0.85A 6hu9a-1ks8A:
0.3
6hu9e-1ks8A:
0.5		 6hu9a-1ks8A:
23.24
6hu9e-1ks8A:
14.05