SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ksx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE501_0
(RNA POLYMERASE
3D-POL)		 1ksx REPLICATION PROTEIN
E1
(Bovine
papillomavirus) 		4 / 4 CYH A 215
THR A 239
PHE A 237
LYS A 241
 None
 1.31A 4k50E-1ksxA:
0.0		 4k50E-1ksxA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_M_ACTM502_0
(RNA POLYMERASE
3D-POL)		 1ksx REPLICATION PROTEIN
E1
(Bovine
papillomavirus) 		4 / 4 CYH A 215
THR A 239
PHE A 237
LYS A 241
 None
 1.32A 4k50M-1ksxA:
0.0		 4k50M-1ksxA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ksx REPLICATION PROTEIN
E1
(Bovine
papillomavirus) 		5 / 7 ILE A 235
PHE A 237
ARG A 247
MET A 250
LEU A 254
 None
 1.37A 5iy5N-1ksxA:
0.0
5iy5W-1ksxA:
0.0		 5iy5N-1ksxA:
14.35
5iy5W-1ksxA:
20.16