SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 4 LEU A  74
ARG A 129
LEU A 128
ALA A 122
 None
 1.16A 3b9mA-1kt9A:
undetectable		 3b9mA-1kt9A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 7 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.94A 3d2tA-1kt9A:
undetectable		 3d2tA-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 6 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.93A 3d2tB-1kt9A:
0.0		 3d2tB-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 7 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.78A 3ozkB-1kt9A:
0.2		 3ozkB-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 8 ALA A  57
THR A  53
LEU A  64
LEU A  92
 None
 0.81A 4ejgB-1kt9A:
undetectable		 4ejgB-1kt9A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 8 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.88A 4iizB-1kt9A:
undetectable		 4iizB-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 8 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.90A 4ik6B-1kt9A:
0.0		 4ik6B-1kt9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1kt9 DIADENOSINE
TETRAPHOSPHATE
HYDROLASE
(Caenorhabditis
elegans) 		4 / 6 LYS A  86
ALA A   6
LEU A   8
VAL A  39
 None
 0.83A 5a6iA-1kt9A:
0.0		 5a6iA-1kt9A:
19.31