SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ktm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1ktm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 11 LEU A 998
VAL A 933
ALA A 935
MET A 939
LEU A1028
 None
 1.07A 2c12F-1ktmA:
2.7		 2c12F-1ktmA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 1ktm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 9 LEU A1022
ILE A 937
ALA A1029
GLU A 957
LEU A 998
 None
 1.26A 2v0mB-1ktmA:
undetectable		 2v0mB-1ktmA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 1ktm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 8 VAL A 958
ALA A 935
MET A 939
ASP A1031
LEU A1028
 None
 1.47A 4l9iB-1ktmA:
4.8		 4l9iB-1ktmA:
14.06