SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ktw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.10A 1dz4A-1ktwA:
0.0		 1dz4A-1ktwA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.14A 1dz4A-1ktwA:
0.0		 1dz4A-1ktwA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.12A 1dz4B-1ktwA:
0.0		 1dz4B-1ktwA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.15A 1dz4B-1ktwA:
0.0		 1dz4B-1ktwA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 5 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.11A 1dz6B-1ktwA:
0.0		 1dz6B-1ktwA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 5 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.14A 1dz6B-1ktwA:
0.0		 1dz6B-1ktwA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 11 PHE A 263
ALA A 264
VAL A 383
ALA A 301
ALA A 274
 None
 1.07A 1jinA-1ktwA:
0.0		 1jinA-1ktwA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 SER A 294
THR A 384
ASN A 292
ASP A 382
 None
 1.12A 1mxdA-1ktwA:
undetectable		 1mxdA-1ktwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 LEU A 234
GLY A 204
ILE A 172
ALA A 160
PHE A 175
 None
 0.94A 1pbkA-1ktwA:
undetectable		 1pbkA-1ktwA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 PHE A 162
ILE A  73
ILE A 105
VAL A 107
ILE A 172
 None
 0.97A 1r5lA-1ktwA:
0.0		 1r5lA-1ktwA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 8 THR A 438
THR A 450
VAL A 434
VAL A 380
 CA  A   3 (-3.3A)
None
None
None
 0.91A 1t86A-1ktwA:
undetectable		 1t86A-1ktwA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		3 / 3 HIS A 235
ASP A 178
ASN A 180
 None
NA  A  13 (-2.2A)
None
 0.83A 1wg8B-1ktwA:
undetectable		 1wg8B-1ktwA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 ARG A 243
GLY A 219
LYS A 181
THR A 182
 DGS  A 492 (-3.1A)
None
None
NA  A  11 (-3.5A)
 1.32A 2m2oB-1ktwA:
undetectable		 2m2oB-1ktwA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 LEU A  69
ILE A  97
ALA A  57
THR A 116
ASP A  64
 None
 1.19A 2qo4A-1ktwA:
undetectable		 2qo4A-1ktwA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.17A 2zawA-1ktwA:
undetectable		 2zawA-1ktwA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.15A 2zawA-1ktwA:
undetectable		 2zawA-1ktwA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.10A 3fwgA-1ktwA:
0.0		 3fwgA-1ktwA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		3 / 4 SER A 300
GLY A 279
GLU A 310
 None
 0.55A 3raeA-1ktwA:
undetectable
3raeC-1ktwA:
undetectable		 3raeA-1ktwA:
21.56
3raeC-1ktwA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 5 SER A 201
ILE A 262
TYR A 170
GLY A 225
 None
 0.97A 3uboB-1ktwA:
undetectable		 3uboB-1ktwA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 VAL A 135
ILE A 209
ILE A 187
LEU A 164
VAL A 167
 None
 1.03A 3w68C-1ktwA:
undetectable		 3w68C-1ktwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 VAL A 135
ILE A 209
ILE A 187
LEU A 164
VAL A 167
 None
 1.05A 3w68D-1ktwA:
undetectable		 3w68D-1ktwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.13A 3wrhE-1ktwA:
0.0		 3wrhE-1ktwA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.10A 3wrjE-1ktwA:
0.0		 3wrjE-1ktwA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.13A 3wrjE-1ktwA:
0.0		 3wrjE-1ktwA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 7 PHE A 138
VAL A 129
PHE A 127
ILE A 113
 None
 0.90A 3zjqA-1ktwA:
undetectable		 3zjqA-1ktwA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 7 PHE A 138
VAL A 129
PHE A 127
ILE A 113
 None
 0.92A 3zjqB-1ktwA:
undetectable		 3zjqB-1ktwA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.13A 4g3rA-1ktwA:
0.0		 4g3rA-1ktwA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.06A 4g3rB-1ktwA:
0.0		 4g3rB-1ktwA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.10A 4g3rB-1ktwA:
0.0		 4g3rB-1ktwA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 8 MET A 244
LEU A 234
THR A 223
VAL A 189
 None
 0.84A 4iizB-1ktwA:
undetectable		 4iizB-1ktwA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 8 MET A 244
LEU A 234
THR A 223
VAL A 189
 None
 0.81A 4ik6B-1ktwA:
undetectable		 4ik6B-1ktwA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		3 / 4 SER A 300
GLY A 279
GLU A 310
 None
 0.49A 4juoA-1ktwA:
0.0
4juoC-1ktwA:
undetectable		 4juoA-1ktwA:
21.56
4juoC-1ktwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.15A 4kkyX-1ktwA:
0.0		 4kkyX-1ktwA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 107
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.12A 4l4cA-1ktwA:
0.0		 4l4cA-1ktwA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 6 PHE A  94
VAL A 111
VAL A  52
ASP A  65
 None
None
None
CA  A   7 (-2.2A)
 1.13A 4l4cA-1ktwA:
0.0		 4l4cA-1ktwA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		3 / 3 LEU A 159
LEU A 220
ASN A 213
 None
 0.75A 4otwA-1ktwA:
undetectable		 4otwA-1ktwA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 VAL A 161
LEU A  69
LEU A 126
VAL A 107
PHE A 140
 None
 1.05A 4y0rA-1ktwA:
0.0		 4y0rA-1ktwA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 PHE A 140
ILE A 172
ALA A 185
VAL A 161
ILE A 187
 None
None
CL  A 530 (-3.5A)
None
None
 1.11A 5mlmA-1ktwA:
undetectable		 5mlmA-1ktwA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 PHE A  94
GLY A  59
GLY A  90
ILE A  87
LEU A 126
 None
CA  A   7 ( 4.9A)
None
None
None
 1.14A 5ul4A-1ktwA:
undetectable		 5ul4A-1ktwA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 7 GLY A 307
GLN A 222
TYR A 224
ASP A 436
 None
CL  A 530 (-3.7A)
None
CA  A   3 ( 4.5A)
 1.13A 5vlmE-1ktwA:
undetectable		 5vlmE-1ktwA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		5 / 12 SER A 201
PHE A 231
ILE A 221
TYR A 170
ALA A 226
 None
 1.41A 5zwrB-1ktwA:
undetectable		 5zwrB-1ktwA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1ktw IOTA-CARRAGEENASE
(Alteromonas
sp.
ATCC
43554) 		4 / 5 GLN A 289
VAL A 380
PRO A  30
THR A 384
 None
 1.32A 6cduI-1ktwA:
0.0
6cduJ-1ktwA:
undetectable		 6cduI-1ktwA:
22.20
6cduJ-1ktwA:
22.20