SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 ARG A 276
GLY A 280
LEU A 273
VAL A 246
ALA A 182
None
1.16A 1gseA-1kv9A:
undetectable
1gseA-1kv9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 ALA A   6
VAL A   3
TRP A 116
None
0.91A 1jo3A-1kv9A:
undetectable
1jo3A-1kv9A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 ALA A   6
VAL A   3
TRP A 116
None
0.91A 1jo3B-1kv9A:
undetectable
1jo3B-1kv9A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 8 SER A 234
HIS A 381
ILE A 397
SER A 338
None
1.17A 1kb9A-1kv9A:
0.0
1kb9C-1kv9A:
0.0
1kb9D-1kv9A:
3.2
1kb9E-1kv9A:
0.0
1kb9A-1kv9A:
22.67
1kb9C-1kv9A:
19.79
1kb9D-1kv9A:
15.55
1kb9E-1kv9A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 TRP A 522
HIS A 459
MET A 534
None
1.44A 1l5qB-1kv9A:
undetectable
1l5qB-1kv9A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 GLN A 301
GLU A  27
MET A 506
ALA A 504
None
1.35A 1linA-1kv9A:
undetectable
1linA-1kv9A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 8 GLY A 175
GLY A 226
GLY A 227
LEU A 225
None
0.62A 1qzzA-1kv9A:
undetectable
1qzzA-1kv9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 10 LEU A 640
ASP A 638
SER A 639
TYR A 587
PHE A 590
None
1.45A 1rqpA-1kv9A:
undetectable
1rqpA-1kv9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 10 LEU A 640
ASP A 638
SER A 639
TYR A 587
PHE A 590
None
1.45A 1rqpB-1kv9A:
undetectable
1rqpB-1kv9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 10 LEU A 640
ASP A 638
SER A 639
TYR A 587
PHE A 590
None
1.46A 1rqpC-1kv9A:
undetectable
1rqpC-1kv9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 TRP A 522
GLY A 602
ASP A 107
THR A  55
None
1.06A 2aouB-1kv9A:
undetectable
2aouB-1kv9A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 10 PHE A 179
TYR A 183
ARG A 193
GLY A 127
GLY A 123
None
1.12A 2ej3B-1kv9A:
undetectable
2ej3B-1kv9A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 11 ILE A 154
GLY A 112
HIS A  21
THR A 155
GLY A 123
None
None
None
PQQ  A 801 (-2.8A)
None
1.30A 2fn1B-1kv9A:
undetectable
2fn1B-1kv9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 5 THR A 392
SER A 466
PRO A 390
SER A 387
None
1.41A 2hdnA-1kv9A:
0.0
2hdnB-1kv9A:
undetectable
2hdnD-1kv9A:
undetectable
2hdnA-1kv9A:
5.36
2hdnB-1kv9A:
19.31
2hdnD-1kv9A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 5 SER A 387
THR A 392
SER A 466
PRO A 390
None
1.41A 2hdnB-1kv9A:
undetectable
2hdnC-1kv9A:
0.0
2hdnD-1kv9A:
undetectable
2hdnB-1kv9A:
19.31
2hdnC-1kv9A:
5.36
2hdnD-1kv9A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 THR A 529
ASP A 295
SER A 252
None
CA  A 802 (-3.1A)
None
0.86A 2nxeA-1kv9A:
undetectable
2nxeA-1kv9A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 11 LEU A 244
VAL A 161
LEU A  63
ILE A 302
ILE A   8
None
1.13A 2uxoB-1kv9A:
0.0
2uxoB-1kv9A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 THR A 289
PRO A 290
ARG A 365
PRO A 358
None
1.01A 2v2gA-1kv9A:
undetectable
2v2gB-1kv9A:
undetectable
2v2gA-1kv9A:
16.89
2v2gB-1kv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 PRO A 358
THR A 289
PRO A 290
ARG A 365
None
1.04A 2v2gA-1kv9A:
undetectable
2v2gB-1kv9A:
undetectable
2v2gA-1kv9A:
16.89
2v2gB-1kv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 THR A 289
PRO A 290
ARG A 365
PRO A 358
None
1.04A 2v2gC-1kv9A:
undetectable
2v2gD-1kv9A:
undetectable
2v2gC-1kv9A:
16.89
2v2gD-1kv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 PRO A 358
THR A 289
PRO A 290
ARG A 365
None
1.02A 2v2gC-1kv9A:
undetectable
2v2gD-1kv9A:
undetectable
2v2gC-1kv9A:
16.89
2v2gD-1kv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 8 PRO A 358
THR A 289
PRO A 290
ARG A 365
None
1.02A 2v41C-1kv9A:
undetectable
2v41D-1kv9A:
undetectable
2v41C-1kv9A:
16.89
2v41D-1kv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 7 THR A 289
PRO A 290
ARG A 365
PRO A 358
None
1.04A 2v41E-1kv9A:
undetectable
2v41F-1kv9A:
undetectable
2v41E-1kv9A:
16.89
2v41F-1kv9A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 9 LEU A 640
ASP A 638
SER A 639
TYR A 587
PHE A 590
None
1.49A 2v7uA-1kv9A:
0.0
2v7uA-1kv9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1300_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 9 LEU A 640
ASP A 638
SER A 639
TYR A 587
PHE A 590
None
1.49A 2v7uB-1kv9A:
0.0
2v7uB-1kv9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 GLY A  22
MET A 235
TYR A  25
HIS A  21
ARG A 111
None
None
None
None
PQQ  A 801 (-3.3A)
1.35A 2zthA-1kv9A:
undetectable
2zthA-1kv9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 THR A 527
LEU A 528
ASN A 382
VAL A  96
LEU A 125
None
None
PQQ  A 801 (-3.2A)
None
None
1.25A 3a51B-1kv9A:
0.0
3a51B-1kv9A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 THR A 145
SER A 153
LYS A 100
None
PQQ  A 801 ( 4.8A)
None
1.10A 3aocC-1kv9A:
0.0
3aocC-1kv9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 LEU A  63
GLY A 112
MET A 519
ARG A  29
LEU A 545
None
1.40A 3h52A-1kv9A:
undetectable
3h52A-1kv9A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 GLY A 123
ILE A 166
VAL A 165
None
0.51A 3nv6A-1kv9A:
undetectable
3nv6A-1kv9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 GLY A 229
GLY A 227
SER A 270
ALA A 172
ASN A 250
None
None
None
PQQ  A 801 (-3.0A)
CA  A 802 ( 2.9A)
1.40A 3t7sC-1kv9A:
undetectable
3t7sC-1kv9A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 ARG A 365
ARG A 259
ASP A 265
None
0.88A 3wipG-1kv9A:
0.0
3wipH-1kv9A:
0.0
3wipG-1kv9A:
17.49
3wipH-1kv9A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 TYR A 152
GLY A 168
ASN A 169
ILE A 166
LEU A 190
None
1.36A 4kovA-1kv9A:
0.0
4kovA-1kv9A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 5 TYR A 651
ARG A 655
ASP A 430
VAL A 525
None
None
None
PQQ  A 801 (-4.5A)
1.11A 4nkvB-1kv9A:
0.0
4nkvB-1kv9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 4 THR A 507
GLY A 469
ASP A  37
SER A  31
None
1.06A 4rfqA-1kv9A:
undetectable
4rfqA-1kv9A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 8 PHE A 194
ARG A 276
ALA A 283
GLY A 280
None
0.77A 4xk8a-1kv9A:
0.0
4xk8a-1kv9A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 ILE A 605
MET A 539
ASP A 107
HEM  A 901 (-4.2A)
None
None
0.67A 5h2uA-1kv9A:
undetectable
5h2uA-1kv9A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
6 / 12 VAL A 246
ILE A 275
ALA A 274
PHE A 194
VAL A 180
GLY A 168
None
1.41A 5j2tC-1kv9A:
undetectable
5j2tC-1kv9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 TYR A 286
THR A 289
GLY A 249
ALA A 298
THR A 299
None
1.14A 5lf7H-1kv9A:
undetectable
5lf7N-1kv9A:
undetectable
5lf7H-1kv9A:
15.49
5lf7N-1kv9A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 SER A 485
ALA A 486
THR A 392
None
0.75A 5n0xB-1kv9A:
0.0
5n0xB-1kv9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 ILE A 518
LEU A 546
TRP A 493
GLY A 475
GLY A 479
None
1.17A 5nnaA-1kv9A:
undetectable
5nnaA-1kv9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 ILE A 518
LEU A 546
TRP A 493
GLY A 475
GLY A 479
None
1.17A 5nnaB-1kv9A:
undetectable
5nnaB-1kv9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 ILE A 518
LEU A 546
TRP A 493
GLY A 475
GLY A 479
None
1.19A 5nnaC-1kv9A:
undetectable
5nnaC-1kv9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
5 / 12 ILE A 518
LEU A 546
TRP A 493
GLY A 475
GLY A 479
None
1.15A 5nnaD-1kv9A:
0.2
5nnaD-1kv9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 TYR A 286
ALA A 339
TYR A 327
None
0.83A 5uunB-1kv9A:
0.0
5uunB-1kv9A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 4 TYR A 587
GLY A 531
ASN A 535
ARG A 609
None
1.14A 5w7bA-1kv9A:
undetectable
5w7bC-1kv9A:
undetectable
5w7bA-1kv9A:
9.38
5w7bC-1kv9A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 4 TYR A 651
GLY A 530
ASN A 535
ARG A 609
None
1.34A 5w7bA-1kv9A:
undetectable
5w7bC-1kv9A:
undetectable
5w7bA-1kv9A:
9.38
5w7bC-1kv9A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 4 TYR A 651
GLY A 531
ASN A 535
ARG A 609
None
0.88A 5w7bA-1kv9A:
undetectable
5w7bC-1kv9A:
undetectable
5w7bA-1kv9A:
9.38
5w7bC-1kv9A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 GLY A 531
ASN A 535
ARG A 609
None
0.65A 5w7bD-1kv9A:
undetectable
5w7bD-1kv9A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
3 / 3 GLY A 602
ASN A 535
ARG A 609
None
0.72A 5w7bD-1kv9A:
undetectable
5w7bD-1kv9A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida)
4 / 5 GLY A 334
ASP A 330
ARG A 331
GLN A 319
None
1.35A 5zrfB-1kv9A:
undetectable
5zrfB-1kv9A:
22.46