SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 1kve SMK TOXIN
(Millerozyma
farinosa) 		5 / 12 GLY B 187
ILE A  54
ALA B 148
GLY B 209
ILE A  34
 None
 0.88A 1bx4A-1kveB:
undetectable		 1bx4A-1kveB:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		5 / 12 GLY A  39
ALA A  40
ILE A  50
GLY A  57
ALA A  35
 None
 0.89A 2b60A-1kveA:
undetectable		 2b60A-1kveA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		5 / 11 GLY A  39
ALA A  40
ILE A  50
GLY A  57
ALA A  35
 None
 0.81A 2b60B-1kveA:
undetectable		 2b60B-1kveA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		5 / 12 LEU A  21
LEU A  62
ALA A  60
ILE A  61
PHE B 205
 None
 0.85A 2h42C-1kveA:
undetectable		 2h42C-1kveA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		5 / 10 ILE A  61
PHE B 182
MET A  25
LEU A  21
LEU B 177
 None
 0.99A 2w98A-1kveA:
undetectable		 2w98A-1kveA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		4 / 7 PRO B 218
PHE A  65
ILE B 203
GLY A  75
 None
 0.88A 2y7kA-1kveB:
undetectable		 2y7kA-1kveB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 1kve SMK TOXIN
SMK TOXIN
(Millerozyma
farinosa;
Millerozyma
farinosa) 		5 / 10 LEU B 207
ALA B 178
PHE B 182
GLY B 184
ILE A  34
 None
 1.31A 3qpsA-1kveB:
undetectable		 3qpsA-1kveB:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		3 / 3 PHE A  43
LYS B 167
SER B 166
 None
 1.28A 3tyeB-1kveA:
undetectable		 3tyeB-1kveA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1kve SMK TOXIN
SMK TOXIN
(Millerozyma
farinosa;
Millerozyma
farinosa) 		4 / 8 ILE A  58
ILE A  61
PHE A  65
GLY B 155
 None
 0.81A 4ac9C-1kveA:
undetectable		 4ac9C-1kveA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1kve SMK TOXIN
(Millerozyma
farinosa) 		5 / 12 ALA B 189
GLY B 153
GLY B 155
ILE B 203
PRO B 214
 None
 1.01A 4q5mA-1kveB:
undetectable		 4q5mA-1kveB:
18.90