SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kxh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 TYR A  50
LEU A 139
LEU A 142
ALA A 175
HIS A 263
ASP A 264
 ACR  A 598 (-4.5A)
None
ACR  A 598 ( 4.9A)
ACR  A 598 (-3.7A)
None
ACR  A 598 (-3.1A)
 0.68A 1dedA-1kxhA:
29.5		 1dedA-1kxhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		7 / 12 TYR A  50
LEU A 142
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 ACR  A 598 (-4.5A)
ACR  A 598 ( 4.9A)
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.78A 1dedB-1kxhA:
27.0		 1dedB-1kxhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 TYR A  50
GLN A  51
HIS A 178
HIS A 263
ASP A 264
 ACR  A 598 (-4.5A)
ACR  A 598 (-3.7A)
None
None
ACR  A 598 (-3.1A)
 1.16A 1eswA-1kxhA:
13.6		 1eswA-1kxhA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 TYR A  50
GLN A  51
HIS A 263
ASP A 264
TRP A  46
 ACR  A 598 (-4.5A)
ACR  A 598 (-3.7A)
None
ACR  A 598 (-3.1A)
None
 0.96A 1eswA-1kxhA:
13.6		 1eswA-1kxhA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 VAL A 358
ASP A 363
PHE A 290
THR A 232
GLY A 245
 None
 1.21A 1ia0B-1kxhA:
undetectable		 1ia0B-1kxhA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		8 / 12 TRP A  46
TYR A  50
HIS A  89
ARG A 172
LYS A 177
GLU A 200
HIS A 263
ASP A 264
 None
ACR  A 598 (-4.5A)
ACR  A 598 (-3.8A)
CL  A 900 (-4.1A)
None
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.69A 1mxdA-1kxhA:
30.2		 1mxdA-1kxhA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 ILE A 184
LEU A 187
VAL A 191
 None
 0.46A 1mz9B-1kxhA:
undetectable		 1mz9B-1kxhA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 ASP A 306
PHE A 278
GLY A 309
TYR A 305
 None
 0.92A 1rmtC-1kxhA:
undetectable		 1rmtC-1kxhA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 VAL A 358
ASP A 363
PHE A 290
THR A 232
GLY A 245
 None
 1.21A 1tubB-1kxhA:
2.5		 1tubB-1kxhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 LYS A 190
ASP A 146
ASN A 150
 None
 1.13A 2bm9A-1kxhA:
undetectable		 2bm9A-1kxhA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 TYR A  50
SER A  35
TYR A 305
HIS A 263
 ACR  A 598 (-4.5A)
None
None
None
 1.36A 2bteA-1kxhA:
0.0		 2bteA-1kxhA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 8 TYR A  50
SER A  35
TYR A 305
HIS A 263
 ACR  A 598 (-4.5A)
None
None
None
 1.35A 2bteD-1kxhA:
undetectable		 2bteD-1kxhA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 11 TYR A  50
GLN A  51
HIS A 263
ASP A 264
TRP A  46
 ACR  A 598 (-4.5A)
ACR  A 598 (-3.7A)
None
ACR  A 598 (-3.1A)
None
 0.89A 2owcA-1kxhA:
13.2		 2owcA-1kxhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 11 TYR A  50
GLN A  51
HIS A 263
ASP A 264
TRP A  46
 ACR  A 598 (-4.5A)
ACR  A 598 (-3.7A)
None
ACR  A 598 (-3.1A)
None
 0.90A 2owwA-1kxhA:
13.1		 2owwA-1kxhA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 6 LEU A 187
VAL A 191
ILE A 160
ILE A  87
 None
 0.90A 2piwA-1kxhA:
undetectable		 2piwA-1kxhA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 4 GLU A  21
ARG A  73
ASN A  72
ASP A  69
 None
 1.43A 2zq9A-1kxhA:
0.0		 2zq9A-1kxhA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.68A 3aicA-1kxhA:
8.3		 3aicA-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.68A 3aicB-1kxhA:
8.3		 3aicB-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
TYR A  50
 CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
ACR  A 598 (-4.5A)
 0.73A 3aicC-1kxhA:
8.5		 3aicC-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.75A 3aicD-1kxhA:
8.9		 3aicD-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.72A 3aicE-1kxhA:
8.5		 3aicE-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.69A 3aicF-1kxhA:
8.2		 3aicF-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.68A 3aicG-1kxhA:
8.9		 3aicG-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 LEU A 139
ARG A 172
ALA A 175
GLU A 200
HIS A 263
ASP A 264
 None
CL  A 900 (-4.1A)
ACR  A 598 (-3.7A)
ACR  A 598 (-2.8A)
None
ACR  A 598 (-3.1A)
 0.72A 3aicH-1kxhA:
8.5		 3aicH-1kxhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 MET A 302
PHE A   9
THR A 277
PHE A 259
GLY A 271
 None
 1.47A 3aodC-1kxhA:
0.0		 3aodC-1kxhA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		3 / 3 TYR A 159
TYR A 111
ILE A 110
 None
 0.82A 3eteA-1kxhA:
undetectable
3eteB-1kxhA:
undetectable		 3eteA-1kxhA:
21.00
3eteB-1kxhA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 11 GLU A  56
GLY A  97
ALA A  99
ILE A  41
ALA A  91
 None
 1.22A 3nmuB-1kxhA:
0.0
3nmuJ-1kxhA:
undetectable		 3nmuB-1kxhA:
20.75
3nmuJ-1kxhA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 11 ALA A 287
ILE A 342
GLY A 345
PRO A 299
VAL A 258
 None
 1.06A 3oxvD-1kxhA:
undetectable		 3oxvD-1kxhA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 GLY A 377
VAL A 404
ALA A 397
ASP A 395
ASN A 351
 None
 1.20A 3qowA-1kxhA:
undetectable		 3qowA-1kxhA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 SER A  59
PRO A  52
TYR A  50
VAL A  53
 None
None
ACR  A 598 (-4.5A)
None
 1.25A 3sufC-1kxhA:
undetectable		 3sufC-1kxhA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 7 GLU A 222
THR A 221
THR A 217
SER A 255
 None
CL  A 900 ( 4.4A)
None
None
 1.07A 4pfjA-1kxhA:
undetectable		 4pfjA-1kxhA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 ALA A 175
SER A 176
VAL A 257
GLN A  33
PHE A   5
 ACR  A 598 (-3.7A)
None
None
None
None
 1.28A 4zj8A-1kxhA:
undetectable		 4zj8A-1kxhA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 6 PHE A 371
SER A 398
VAL A 423
ASP A 395
 None
 1.23A 5hesA-1kxhA:
undetectable		 5hesA-1kxhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 9 ALA A 287
ILE A 342
GLY A 345
PRO A 299
VAL A 258
 None
 1.01A 5kr0A-1kxhA:
undetectable		 5kr0A-1kxhA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		4 / 5 ALA A 397
VAL A 423
LYS A 446
ILE A 441
 None
 1.01A 5of1B-1kxhA:
undetectable		 5of1B-1kxhA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		7 / 12 TRP A  46
TYR A  50
HIS A  89
GLU A 207
HIS A 178
HIS A 263
ASP A 264
 None
ACR  A 598 (-4.5A)
ACR  A 598 (-3.8A)
None
None
None
ACR  A 598 (-3.1A)
 1.28A 6ag0A-1kxhA:
28.6		 6ag0A-1kxhA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		8 / 12 TRP A  46
TYR A  50
HIS A  89
LEU A 139
LYS A 177
HIS A 178
HIS A 263
ASP A 264
 None
ACR  A 598 (-4.5A)
ACR  A 598 (-3.8A)
None
None
None
None
ACR  A 598 (-3.1A)
 0.80A 6ag0A-1kxhA:
28.6		 6ag0A-1kxhA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 TRP A  46
TYR A  50
TYR A 127
LYS A 177
HIS A 263
ASP A 264
 None
ACR  A 598 (-4.5A)
None
None
None
ACR  A 598 (-3.1A)
 1.03A 6ag0A-1kxhA:
28.6		 6ag0A-1kxhA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 TRP A  46
GLU A 207
LYS A 177
HIS A 178
HIS A 263
ASP A 264
 None
None
None
None
None
ACR  A 598 (-3.1A)
 1.42A 6ag0C-1kxhA:
28.8		 6ag0C-1kxhA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		6 / 12 TRP A  46
LEU A 139
LYS A 177
HIS A 178
HIS A 263
ASP A 264
 None
None
None
None
None
ACR  A 598 (-3.1A)
 0.74A 6ag0C-1kxhA:
28.8		 6ag0C-1kxhA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 10 ALA A 287
ILE A 342
GLY A 345
PRO A 299
VAL A 258
 None
 0.92A 6dj2A-1kxhA:
undetectable		 6dj2A-1kxhA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 1kxh ALPHA-AMYLASE
(Pseudoalteromona
s
haloplanktis) 		5 / 12 THR A 221
VAL A 197
GLY A 270
ASP A  84
ASN A 174
 CL  A 900 ( 4.4A)
None
None
None
ACR  A 598 (-3.2A)
 1.16A 6gngA-1kxhA:
undetectable		 6gngA-1kxhA:
21.79