SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)		 1kxq ANTIBODY VHH
FRAGMENT CABAMD9
(Camelus
dromedarius) 		4 / 4 GLY E  44
GLU E  43
ASP E  59
TYR E  56
 None
 1.45A 2yvlC-1kxqE:
undetectable		 2yvlC-1kxqE:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 1kxq ANTIBODY VHH
FRAGMENT CABAMD9
(Camelus
dromedarius) 		4 / 8 GLU E 105
TYR E 107
TYR E  56
PHE E  34
 None
 1.06A 3jz0B-1kxqE:
undetectable		 3jz0B-1kxqE:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 1kxq ANTIBODY VHH
FRAGMENT CABAMD9
(Camelus
dromedarius) 		3 / 3 TRP E 110
GLN E   3
THR E  95
 None
 0.69A 4m2xA-1kxqE:
undetectable		 4m2xA-1kxqE:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1kxq ANTIBODY VHH
FRAGMENT CABAMD9
(Camelus
dromedarius) 		3 / 3 SER E  25
ALA E  24
THR E  95
 None
 0.73A 5n0xB-1kxqE:
undetectable		 5n0xB-1kxqE:
14.11