SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ky3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 1ky3 GTP-BINDING PROTEIN
YPT7P
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 110
PHE A 119
PHE A 121
 None
 0.77A 3lk0D-1ky3A:
0.0		 3lk0D-1ky3A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1ky3 GTP-BINDING PROTEIN
YPT7P
(Saccharomyces
cerevisiae) 		3 / 3 GLY A  18
GLY A  20
THR A  22
 GDP  A 400 (-3.6A)
GDP  A 400 (-3.2A)
MG  A 401 ( 3.1A)
 0.45A 3si7B-1ky3A:
undetectable		 3si7B-1ky3A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 1ky3 GTP-BINDING PROTEIN
YPT7P
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 137
LEU A 145
ASN A  93
ASP A  90
 None
 1.15A 5vcyA-1ky3A:
undetectable		 5vcyA-1ky3A:
20.77