SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Z_B_ROCB505_1 (PROTEIN (PROTEASE))	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 38 ALA A 39 ILE A 118 GLY A 120 ILE A 22	None	1.00A	1c6zA-1kz1A: undetectable	1c6zA-1kz1A: 24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Z_B_ROCB505_2 (PROTEIN (PROTEASE))	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 38 ALA A 39 ILE A 118 GLY A 120 ILE A 22	None	0.95A	1c6zB-1kz1A: undetectable	1c6zB-1kz1A: 24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HSH_A_MK1A401_2 (HIV-II PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 9	ALA A 150 GLY A 83 ILE A 84 ILE A 54 ILE A 20	None	0.93A	1hshB-1kz1A: undetectable	1hshB-1kz1A: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HSH_C_MK1C402_2 (HIV-II PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 8	ALA A 150 GLY A 83 ILE A 84 ILE A 54 ILE A 20	None	0.81A	1hshD-1kz1A: undetectable	1hshD-1kz1A: 25.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KYV_A_RBFA501_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	7 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94 ILE A 98	None	0.21A	1kyvA-1kz1A: 30.1 1kyvE-1kz1A: 29.6	1kyvA-1kz1A: 99.37 1kyvE-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KYV_B_RBFB502_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	6 / 11	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94	None	0.12A	1kyvA-1kz1A: 30.1 1kyvB-1kz1A: 30.0	1kyvA-1kz1A: 99.37 1kyvB-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KYV_B_RBFB502_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 11	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 121	None	1.39A	1kyvA-1kz1A: 30.1 1kyvB-1kz1A: 30.0	1kyvA-1kz1A: 99.37 1kyvB-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KYV_C_RBFC503_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	7 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94 ILE A 98	None	0.19A	1kyvB-1kz1A: 30.0 1kyvC-1kz1A: 29.9	1kyvB-1kz1A: 99.37 1kyvC-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KYV_D_RBFD504_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	7 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94 ILE A 98	None	0.19A	1kyvC-1kz1A: 29.9 1kyvD-1kz1A: 30.1	1kyvC-1kz1A: 99.37 1kyvD-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1KYV_E_RBFE505_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	7 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94 ILE A 98	None	0.16A	1kyvD-1kz1A: 30.1 1kyvE-1kz1A: 29.6	1kyvD-1kz1A: 99.37 1kyvE-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_A_RBFA300_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	6 / 11	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94	None	0.17A	2a58A-1kz1A: 29.7 2a58E-1kz1A: 29.8	2a58A-1kz1A: 99.37 2a58E-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_A_RBFA300_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 11	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 121	None	1.40A	2a58A-1kz1A: 29.7 2a58E-1kz1A: 29.8	2a58A-1kz1A: 99.37 2a58E-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_B_RBFB301_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	6 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94	None	0.17A	2a58A-1kz1A: 29.7 2a58B-1kz1A: 29.7	2a58A-1kz1A: 99.37 2a58B-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_B_RBFB301_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	ILE A 118 LEU A 119 HIS A 142 TRP A 146 ALA A 149	None	0.25A	2a58A-1kz1A: 29.7 2a58B-1kz1A: 29.7	2a58A-1kz1A: 99.37 2a58B-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_C_RBFC302_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	6 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94	None	0.16A	2a58B-1kz1A: 29.7 2a58C-1kz1A: 29.7	2a58B-1kz1A: 99.37 2a58C-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_C_RBFC302_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	ILE A 118 LEU A 119 HIS A 142 TRP A 146 ALA A 149	None	0.25A	2a58B-1kz1A: 29.7 2a58C-1kz1A: 29.7	2a58B-1kz1A: 99.37 2a58C-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_D_RBFD303_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	6 / 11	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94	None	0.16A	2a58C-1kz1A: 29.7 2a58D-1kz1A: 29.7	2a58C-1kz1A: 99.37 2a58D-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_D_RBFD303_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 11	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 121	None	1.41A	2a58C-1kz1A: 29.7 2a58D-1kz1A: 29.7	2a58C-1kz1A: 99.37 2a58D-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_E_RBFE304_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	6 / 12	GLY A 61 SER A 62 TRP A 63 GLU A 64 LEU A 87 HIS A 94	None	0.17A	2a58D-1kz1A: 29.7 2a58E-1kz1A: 29.8	2a58D-1kz1A: 99.37 2a58E-1kz1A: 99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2A58_E_RBFE304_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	ILE A 118 LEU A 119 HIS A 142 TRP A 146 ALA A 149	None	0.25A	2a58D-1kz1A: 29.7 2a58E-1kz1A: 29.8	2a58D-1kz1A: 99.37 2a58E-1kz1A: 99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AQU_B_DR7B300_1 (HIV-1 PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 10	GLY A 147 ALA A 150 GLY A 83 ILE A 84 ILE A 20	None	0.99A	2aquA-1kz1A: undetectable	2aquA-1kz1A: 28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B60_B_RITB100_1 (GAG-POL POLYPROTEIN)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 147 ALA A 150 GLY A 83 ILE A 84 ILE A 20	None	0.91A	2b60A-1kz1A: undetectable	2b60A-1kz1A: 24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_C_SAMC300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 83 GLY A 120 GLY A 143 ILE A 69 VAL A 117	None	0.98A	2oxtC-1kz1A: undetectable	2oxtC-1kz1A: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q9R_A_BEZA203_0 (PROTEIN OF UNKNOWN FUNCTION)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	4 / 5	LEU A 35 GLY A 38 ILE A 22 ILE A 84	None	0.84A	2q9rA-1kz1A: undetectable	2q9rA-1kz1A: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHC_B_AB1B9001_2 (PROTEASE RETROPEPSIN)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 147 ALA A 150 GLY A 83 ILE A 84 ILE A 20	None	0.95A	2qhcB-1kz1A: undetectable	2qhcB-1kz1A: 28.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R5Q_D_1UND900_2 (PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 10	GLY A 147 ALA A 150 GLY A 83 ILE A 84 ILE A 20	None	0.94A	2r5qD-1kz1A: undetectable	2r5qD-1kz1A: 26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RKF_A_AB1A501_1 (PROTEASE RETROPEPSIN)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 147 ALA A 150 GLY A 83 ILE A 84 ILE A 20	None	0.92A	2rkfA-1kz1A: undetectable	2rkfA-1kz1A: 24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WD9_A_IBPA1570_1 (ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	4 / 7	ILE A 88 LEU A 87 GLY A 85 GLY A 27	None	0.82A	2wd9A-1kz1A: 2.9	2wd9A-1kz1A: 14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_A_ADNA1301_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	4 / 7	GLU A 33 ALA A 130 PRO A 34 ALA A 134	None	1.12A	2zgwA-1kz1A: undetectable	2zgwA-1kz1A: 24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_B_ADNB1302_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	4 / 6	GLU A 33 ALA A 130 PRO A 34 ALA A 134	None	1.12A	2zgwB-1kz1A: undetectable	2zgwB-1kz1A: 24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKP_B_478B200_1 (PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 8	GLY A 147 ALA A 150 GLY A 83 ILE A 84 ILE A 20	None	1.04A	3ekpA-1kz1A: undetectable	3ekpA-1kz1A: 28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM4_A_DR7A100_1 (PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 11	GLY A 38 ALA A 39 ILE A 118 LEU A 122 ILE A 22	None	0.92A	3em4A-1kz1A: undetectable	3em4A-1kz1A: 29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_B_CELB1701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	LEU A 35 LEU A 29 TRP A 146 ILE A 22 GLY A 83	None	1.17A	3kk6B-1kz1A: undetectable	3kk6B-1kz1A: 16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDX_A_RITA100_1 (PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	GLY A 38 ALA A 39 ILE A 118 GLY A 120 ILE A 22	None	1.00A	3ndxA-1kz1A: undetectable	3ndxA-1kz1A: 29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_A_PXLA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	4 / 7	GLY A 147 ASP A 145 GLY A 143 HIS A 140	None	0.86A	4c5nA-1kz1A: 3.2	4c5nA-1kz1A: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EAT_B_BEZB1000_0 (BENZOATE-COENZYME A LIGASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 9	ALA A 150 ALA A 39 GLY A 143 ILE A 84 ILE A 22	None	1.14A	4eatB-1kz1A: 2.0	4eatB-1kz1A: 15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_A_STRA604_1 (CYTOCHROME P450 21-HYDROXYLASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	SER A 62 VAL A 36 LEU A 35 ILE A 84 VAL A 124	None	1.11A	4y8wA-1kz1A: undetectable	4y8wA-1kz1A: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_B_STRB603_1 (CYTOCHROME P450 21-HYDROXYLASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	SER A 62 VAL A 36 LEU A 35 ILE A 84 GLY A 120	None	1.02A	4y8wB-1kz1A: undetectable	4y8wB-1kz1A: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E5J_A_017A201_2 (PROTEASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	ALA A 150 GLY A 83 ILE A 84 ILE A 54 ILE A 20	None	0.85A	5e5jB-1kz1A: undetectable	5e5jB-1kz1A: 27.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	VAL A 86 LEU A 122 ALA A 134 ILE A 54 ILE A 84	None	1.18A	5hbsA-1kz1A: undetectable	5hbsA-1kz1A: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	4 / 7	GLY A 68 VAL A 117 ILE A 82 VAL A 81	None	0.79A	5ik1A-1kz1A: undetectable	5ik1A-1kz1A: 18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_C_HISC402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 9	VAL A 117 LEU A 106 GLY A 85 LEU A 121 VAL A 23	None	1.11A	6czmB-1kz1A: 1.5 6czmC-1kz1A: 1.7	6czmB-1kz1A: 21.09 6czmC-1kz1A: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_F_HISF402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 10	VAL A 117 LEU A 106 GLY A 85 LEU A 121 VAL A 23	None	1.19A	6czmE-1kz1A: 0.1 6czmF-1kz1A: 0.0	6czmE-1kz1A: 21.09 6czmF-1kz1A: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	1kz1	6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE (Schizosaccharomy ces pombe)	5 / 12	ILE A 84 ASN A 141 GLY A 147 ALA A 149 ASP A 145	None	1.10A	6dwnD-1kz1A: 0.0	6dwnD-1kz1A: 23.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C6Z_B_ROCB505_1","PROTEIN (PROTEASE);PROTEIN (PROTEASE)","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  38;ALA A  39;ILE A 118;GLY A 120;ILE A  22","None","1.00A","1c6zA-1kz1A:undetectable","1c6zA-1kz1A:24.50"],["1C6Z_B_ROCB505_2","PROTEIN (PROTEASE)","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  38;ALA A  39;ILE A 118;GLY A 120;ILE A  22","None","0.95A","1c6zB-1kz1A:undetectable","1c6zB-1kz1A:24.50"],["1HSH_A_MK1A401_2","HIV-II PROTEASE;HIV-II PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ALA A 150;GLY A  83;ILE A  84;ILE A  54;ILE A  20","None","0.93A","1hshB-1kz1A:undetectable","1hshB-1kz1A:25.81"],["1HSH_C_MK1C402_2","HIV-II PROTEASE;HIV-II PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ALA A 150;GLY A  83;ILE A  84;ILE A  54;ILE A  20","None","0.81A","1hshD-1kz1A:undetectable","1hshD-1kz1A:25.81"],["1KYV_A_RBFA501_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",7,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94;ILE A  98","None","0.21A","1kyvA-1kz1A:30.1;1kyvE-1kz1A:29.6","1kyvA-1kz1A:99.37;1kyvE-1kz1A:99.37"],["1KYV_B_RBFB502_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",6,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94","None","0.12A","1kyvA-1kz1A:30.1;1kyvB-1kz1A:30.0","1kyvA-1kz1A:99.37;1kyvB-1kz1A:99.37"],["1KYV_B_RBFB502_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A 121","None","1.39A","1kyvA-1kz1A:30.1;1kyvB-1kz1A:30.0","1kyvA-1kz1A:99.37;1kyvB-1kz1A:99.37"],["1KYV_C_RBFC503_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",7,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94;ILE A  98","None","0.19A","1kyvB-1kz1A:30.0;1kyvC-1kz1A:29.9","1kyvB-1kz1A:99.37;1kyvC-1kz1A:99.37"],["1KYV_D_RBFD504_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",7,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94;ILE A  98","None","0.19A","1kyvC-1kz1A:29.9;1kyvD-1kz1A:30.1","1kyvC-1kz1A:99.37;1kyvD-1kz1A:99.37"],["1KYV_E_RBFE505_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",7,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94;ILE A  98","None","0.16A","1kyvD-1kz1A:30.1;1kyvE-1kz1A:29.6","1kyvD-1kz1A:99.37;1kyvE-1kz1A:99.37"],["2A58_A_RBFA300_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",6,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94","None","0.17A","2a58A-1kz1A:29.7;2a58E-1kz1A:29.8","2a58A-1kz1A:99.37;2a58E-1kz1A:99.37"],["2A58_A_RBFA300_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A 121","None","1.40A","2a58A-1kz1A:29.7;2a58E-1kz1A:29.8","2a58A-1kz1A:99.37;2a58E-1kz1A:99.37"],["2A58_B_RBFB301_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",6,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94","None","0.17A","2a58A-1kz1A:29.7;2a58B-1kz1A:29.7","2a58A-1kz1A:99.37;2a58B-1kz1A:99.37"],["2A58_B_RBFB301_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ILE A 118;LEU A 119;HIS A 142;TRP A 146;ALA A 149","None","0.25A","2a58A-1kz1A:29.7;2a58B-1kz1A:29.7","2a58A-1kz1A:99.37;2a58B-1kz1A:99.37"],["2A58_C_RBFC302_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",6,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94","None","0.16A","2a58B-1kz1A:29.7;2a58C-1kz1A:29.7","2a58B-1kz1A:99.37;2a58C-1kz1A:99.37"],["2A58_C_RBFC302_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ILE A 118;LEU A 119;HIS A 142;TRP A 146;ALA A 149","None","0.25A","2a58B-1kz1A:29.7;2a58C-1kz1A:29.7","2a58B-1kz1A:99.37;2a58C-1kz1A:99.37"],["2A58_D_RBFD303_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",6,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94","None","0.16A","2a58C-1kz1A:29.7;2a58D-1kz1A:29.7","2a58C-1kz1A:99.37;2a58D-1kz1A:99.37"],["2A58_D_RBFD303_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A 121","None","1.41A","2a58C-1kz1A:29.7;2a58D-1kz1A:29.7","2a58C-1kz1A:99.37;2a58D-1kz1A:99.37"],["2A58_E_RBFE304_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",6,"GLY A  61;SER A  62;TRP A  63;GLU A  64;LEU A  87;HIS A  94","None","0.17A","2a58D-1kz1A:29.7;2a58E-1kz1A:29.8","2a58D-1kz1A:99.37;2a58E-1kz1A:99.37"],["2A58_E_RBFE304_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ILE A 118;LEU A 119;HIS A 142;TRP A 146;ALA A 149","None","0.25A","2a58D-1kz1A:29.7;2a58E-1kz1A:29.8","2a58D-1kz1A:99.37;2a58E-1kz1A:99.37"],["2AQU_B_DR7B300_1","HIV-1 PROTEASE;HIV-1 PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A 147;ALA A 150;GLY A  83;ILE A  84;ILE A  20","None","0.99A","2aquA-1kz1A:undetectable","2aquA-1kz1A:28.36"],["2B60_B_RITB100_1","GAG-POL POLYPROTEIN;GAG-POL POLYPROTEIN","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A 147;ALA A 150;GLY A  83;ILE A  84;ILE A  20","None","0.91A","2b60A-1kz1A:undetectable","2b60A-1kz1A:24.67"],["2OXT_C_SAMC300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  83;GLY A 120;GLY A 143;ILE A  69;VAL A 117","None","0.98A","2oxtC-1kz1A:undetectable","2oxtC-1kz1A:21.74"],["2Q9R_A_BEZA203_0","PROTEIN OF UNKNOWN FUNCTION","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",4,"LEU A  35;GLY A  38;ILE A  22;ILE A  84","None","0.84A","2q9rA-1kz1A:undetectable","2q9rA-1kz1A:23.15"],["2QHC_B_AB1B9001_2","PROTEASE RETROPEPSIN","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A 147;ALA A 150;GLY A  83;ILE A  84;ILE A  20","None","0.95A","2qhcB-1kz1A:undetectable","2qhcB-1kz1A:28.36"],["2R5Q_D_1UND900_2","PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A 147;ALA A 150;GLY A  83;ILE A  84;ILE A  20","None","0.94A","2r5qD-1kz1A:undetectable","2r5qD-1kz1A:26.87"],["2RKF_A_AB1A501_1","PROTEASE RETROPEPSIN","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A 147;ALA A 150;GLY A  83;ILE A  84;ILE A  20","None","0.92A","2rkfA-1kz1A:undetectable","2rkfA-1kz1A:24.00"],["2WD9_A_IBPA1570_1","ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",4,"ILE A  88;LEU A  87;GLY A  85;GLY A  27","None","0.82A","2wd9A-1kz1A:2.9","2wd9A-1kz1A:14.41"],["2ZGW_A_ADNA1301_1","BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",4,"GLU A  33;ALA A 130;PRO A  34;ALA A 134","None","1.12A","2zgwA-1kz1A:undetectable","2zgwA-1kz1A:24.08"],["2ZGW_B_ADNB1302_1","BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",4,"GLU A  33;ALA A 130;PRO A  34;ALA A 134","None","1.12A","2zgwB-1kz1A:undetectable","2zgwB-1kz1A:24.08"],["3EKP_B_478B200_1","PROTEASE;PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A 147;ALA A 150;GLY A  83;ILE A  84;ILE A  20","None","1.04A","3ekpA-1kz1A:undetectable","3ekpA-1kz1A:28.15"],["3EM4_A_DR7A100_1","PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  38;ALA A  39;ILE A 118;LEU A 122;ILE A  22","None","0.92A","3em4A-1kz1A:undetectable","3em4A-1kz1A:29.41"],["3KK6_B_CELB1701_1","PROSTAGLANDIN G\/H SYNTHASE 1","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"LEU A  35;LEU A  29;TRP A 146;ILE A  22;GLY A  83","None","1.17A","3kk6B-1kz1A:undetectable","3kk6B-1kz1A:16.18"],["3NDX_A_RITA100_1","PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"GLY A  38;ALA A  39;ILE A 118;GLY A 120;ILE A  22","None","1.00A","3ndxA-1kz1A:undetectable","3ndxA-1kz1A:29.85"],["4C5N_A_PXLA300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",4,"GLY A 147;ASP A 145;GLY A 143;HIS A 140","None","0.86A","4c5nA-1kz1A:3.2","4c5nA-1kz1A:21.40"],["4EAT_B_BEZB1000_0","BENZOATE-COENZYME A LIGASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ALA A 150;ALA A  39;GLY A 143;ILE A  84;ILE A  22","None","1.14A","4eatB-1kz1A:2.0","4eatB-1kz1A:15.08"],["4Y8W_A_STRA604_1","CYTOCHROME P450 21-HYDROXYLASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"SER A  62;VAL A  36;LEU A  35;ILE A  84;VAL A 124","None","1.11A","4y8wA-1kz1A:undetectable","4y8wA-1kz1A:18.14"],["4Y8W_B_STRB603_1","CYTOCHROME P450 21-HYDROXYLASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"SER A  62;VAL A  36;LEU A  35;ILE A  84;GLY A 120","None","1.02A","4y8wB-1kz1A:undetectable","4y8wB-1kz1A:18.14"],["5E5J_A_017A201_2","PROTEASE;PROTEASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ALA A 150;GLY A  83;ILE A  84;ILE A  54;ILE A  20","None","0.85A","5e5jB-1kz1A:undetectable","5e5jB-1kz1A:27.82"],["5HBS_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"VAL A  86;LEU A 122;ALA A 134;ILE A  54;ILE A  84","None","1.18A","5hbsA-1kz1A:undetectable","5hbsA-1kz1A:20.23"],["5IK1_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",4,"GLY A  68;VAL A 117;ILE A  82;VAL A  81","None","0.79A","5ik1A-1kz1A:undetectable","5ik1A-1kz1A:18.72"],["6CZM_C_HISC402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"VAL A 117;LEU A 106;GLY A  85;LEU A 121;VAL A  23","None","1.11A","6czmB-1kz1A:1.5;6czmC-1kz1A:1.7","6czmB-1kz1A:21.09;6czmC-1kz1A:21.09"],["6CZM_F_HISF402_0","ATP PHOSPHORIBOSYLTRANSFERASE CATALYTIC SUBUNIT","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"VAL A 117;LEU A 106;GLY A  85;LEU A 121;VAL A  23","None","1.19A","6czmE-1kz1A:0.1;6czmF-1kz1A:0.0","6czmE-1kz1A:21.09;6czmF-1kz1A:21.09"],["6DWN_D_AQ4D602_0","CYTOCHROME P450 1A1","1kz1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","Schizosaccharomyces pombe",5,"ILE A  84;ASN A 141;GLY A 147;ALA A 149;ASP A 145","None","1.10A","6dwnD-1kz1A:0.0","6dwnD-1kz1A:23.46"]]