SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kzq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		5 / 11 LEU A  32
GLY A 112
ILE A 114
SER A 121
THR A  18
 None
 1.25A 3bjwB-1kzqA:
undetectable		 3bjwB-1kzqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		5 / 12 LEU A  32
GLY A 112
ILE A 114
SER A 121
THR A  18
 None
 1.19A 3bjwF-1kzqA:
undetectable		 3bjwF-1kzqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		5 / 11 LEU A  32
GLY A 112
ILE A 114
SER A 121
THR A  18
 None
 1.25A 3bjwH-1kzqA:
undetectable		 3bjwH-1kzqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		3 / 3 ARG A  51
TRP A  81
ILE A  93
 None
 1.06A 4mwxA-1kzqA:
undetectable		 4mwxA-1kzqA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		3 / 3 SER A 133
ALA A 140
VAL A 139
 None
 0.62A 4o2bA-1kzqA:
undetectable		 4o2bA-1kzqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		3 / 3 SER A 133
ALA A 140
VAL A 139
 None
 0.65A 4o2bC-1kzqA:
undetectable		 4o2bC-1kzqA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1kzq MAJOR SURFACE
ANTIGEN P30
(Toxoplasma
gondii) 		3 / 3 SER A 133
ALA A 140
VAL A 139
 None
 0.41A 4x20C-1kzqA:
undetectable		 4x20C-1kzqA:
20.64