SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 6 LEU A 145
ILE A  69
GLU A  77
PRO A 137
 None
 1.22A 1ditH-1l1fA:
0.0
1ditP-1l1fA:
undetectable		 1ditH-1l1fA:
19.52
1ditP-1l1fA:
3.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 LYS A 249
VAL A 253
ALA A 329
ILE A 327
ILE A 325
 None
 0.77A 1epbA-1l1fA:
undetectable		 1epbA-1l1fA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 6 SER A 174
THR A 175
PHE A 152
GLY A 132
 None
 1.04A 1icuA-1l1fA:
0.0
1icuB-1l1fA:
0.0		 1icuA-1l1fA:
19.29
1icuB-1l1fA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 6 PHE A 152
GLY A 132
SER A 174
THR A 175
 None
 1.07A 1icuA-1l1fA:
0.0
1icuB-1l1fA:
0.0		 1icuA-1l1fA:
19.29
1icuB-1l1fA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 PHE A 152
GLY A 132
SER A 174
THR A 175
 None
 1.06A 1icuC-1l1fA:
0.0
1icuD-1l1fA:
0.0		 1icuC-1l1fA:
19.29
1icuD-1l1fA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_B_NIOB702_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 PHE A 152
GLY A 132
SER A 174
THR A 175
 None
 1.08A 1icvA-1l1fA:
0.7
1icvB-1l1fA:
0.0		 1icvA-1l1fA:
19.29
1icvB-1l1fA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 6 SER A 174
THR A 175
PHE A 152
GLY A 132
 None
 1.02A 1kqbA-1l1fA:
0.0
1kqbB-1l1fA:
0.0		 1kqbA-1l1fA:
19.52
1kqbB-1l1fA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 6 SER A 174
THR A 175
PHE A 152
GLY A 132
 None
 1.00A 1kqbC-1l1fA:
0.0
1kqbD-1l1fA:
0.0		 1kqbC-1l1fA:
19.52
1kqbD-1l1fA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 6 PHE A 152
GLY A 132
SER A 174
THR A 175
 None
 1.01A 1kqbC-1l1fA:
0.0
1kqbD-1l1fA:
0.0		 1kqbC-1l1fA:
19.52
1kqbD-1l1fA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 GLY A 255
GLN A 254
VAL A 252
SER A 283
 None
 1.34A 1p6kB-1l1fA:
0.0		 1p6kB-1l1fA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 11 MET A 461
GLY A 214
VAL A 453
SER A 217
ILE A 212
 None
 1.26A 1pk9C-1l1fA:
2.4		 1pk9C-1l1fA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 9 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.17A 1pxxB-1l1fA:
undetectable		 1pxxB-1l1fA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 10 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.19A 1pxxD-1l1fA:
undetectable		 1pxxD-1l1fA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 7 THR A 116
TYR A 117
ASN A 488
LEU A 375
 None
 1.05A 1qzrA-1l1fA:
0.0		 1qzrA-1l1fA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 GLY A 255
GLN A 254
VAL A 252
SER A 283
 None
 1.33A 1rs6B-1l1fA:
0.0		 1rs6B-1l1fA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 8 ALA A 200
GLY A 210
GLY A 211
ILE A 212
ALA A 170
 None
 1.13A 1sguA-1l1fA:
undetectable		 1sguA-1l1fA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 GLY A 255
GLN A 254
VAL A 252
SER A 283
 None
 1.35A 1zzuB-1l1fA:
0.0		 1zzuB-1l1fA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		3 / 3 TRP A 182
THR A 175
TYR A  99
 None
 0.71A 2a3aA-1l1fA:
undetectable		 2a3aA-1l1fA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		3 / 3 TRP A 182
THR A 175
TYR A  99
 None
 0.70A 2a3aB-1l1fA:
undetectable		 2a3aB-1l1fA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		3 / 3 TRP A 182
THR A 175
TYR A  99
 None
 0.70A 2a3bA-1l1fA:
undetectable		 2a3bA-1l1fA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		3 / 3 ASP A 374
ASN A 378
THR A 383
 None
 0.71A 2q63B-1l1fA:
undetectable		 2q63B-1l1fA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 GLY A 192
ALA A 198
GLY A 165
ILE A 166
PRO A 169
 None
 1.17A 3gguA-1l1fA:
undetectable		 3gguA-1l1fA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		6 / 12 GLY A 192
ALA A 198
GLY A 165
ILE A 166
PRO A 169
ILE A 183
 None
 1.23A 3s54A-1l1fA:
undetectable		 3s54A-1l1fA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		6 / 12 GLY A 192
ALA A 198
GLY A 165
ILE A 166
PRO A 169
ILE A 183
 None
 1.18A 3s54B-1l1fA:
undetectable		 3s54B-1l1fA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 11 MET A 461
GLY A 214
VAL A 453
SER A 217
ILE A 212
 None
 1.24A 3uawA-1l1fA:
undetectable		 3uawA-1l1fA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.15A 4coxA-1l1fA:
0.3		 4coxA-1l1fA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.15A 4coxB-1l1fA:
0.8		 4coxB-1l1fA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.16A 4coxD-1l1fA:
0.0		 4coxD-1l1fA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 4 LEU A 377
ILE A 468
GLY A 226
PHE A 230
 None
 1.12A 4dc3A-1l1fA:
undetectable		 4dc3A-1l1fA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		3 / 3 TYR A 187
GLY A 163
PRO A 164
 None
 0.52A 4qwpA-1l1fA:
0.4		 4qwpA-1l1fA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 TYR A 376
ILE A 327
GLY A 351
VAL A 223
ILE A 227
 None
 0.97A 4rvdA-1l1fA:
4.2		 4rvdA-1l1fA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 TYR A 376
ILE A 327
GLY A 351
VAL A 223
ILE A 227
 None
 0.97A 4rvgA-1l1fA:
4.2		 4rvgA-1l1fA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		3 / 3 GLU A 320
ILE A 363
ALA A 345
 None
 0.62A 4wnwB-1l1fA:
0.0		 4wnwB-1l1fA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 4 GLY A 260
VAL A 253
PHE A 298
ILE A 305
 None
 1.17A 4xv2B-1l1fA:
0.0		 4xv2B-1l1fA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 PHE A  67
ILE A 135
GLY A  81
ILE A 148
 None
 0.82A 5dzkB-1l1fA:
undetectable
5dzkI-1l1fA:
undetectable
5dzkW-1l1fA:
undetectable		 5dzkB-1l1fA:
19.51
5dzkI-1l1fA:
19.56
5dzkW-1l1fA:
0.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 PHE A  67
ILE A 135
GLY A  81
ILE A 148
 None
 0.84A 5dzkd-1l1fA:
2.9
5dzkk-1l1fA:
0.2
5dzky-1l1fA:
undetectable		 5dzkd-1l1fA:
19.51
5dzkk-1l1fA:
19.56
5dzky-1l1fA:
0.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		6 / 12 GLY A 192
ALA A 198
GLY A 165
ILE A 166
PRO A 169
ILE A 183
 None
 1.28A 5e5jB-1l1fA:
undetectable		 5e5jB-1l1fA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.07A 5ikqA-1l1fA:
0.0		 5ikqA-1l1fA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.05A 5ikqB-1l1fA:
0.0		 5ikqB-1l1fA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.07A 5iktA-1l1fA:
undetectable		 5iktA-1l1fA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 12 VAL A 121
LEU A 457
VAL A 382
GLY A 380
ALA A 379
 None
 1.05A 5iktB-1l1fA:
0.0		 5iktB-1l1fA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 8 ILE A 372
LEU A 377
ILE A 227
ILE A 231
ASN A 232
 None
 1.23A 5numA-1l1fA:
undetectable		 5numA-1l1fA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 GLY A 255
GLN A 254
VAL A 252
SER A 283
 None
 1.41A 5vunA-1l1fA:
0.0		 5vunA-1l1fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		4 / 5 TYR A 376
MET A 461
THR A 460
LEU A 457
 None
 1.41A 5x19J-1l1fA:
0.0		 5x19J-1l1fA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1l1f GLUTAMATE
DEHYDROGENASE 1
(Homo
sapiens) 		5 / 11 GLY A 214
THR A 383
ARG A 269
PHE A 224
GLY A 220
 None
 1.27A 6nknA-1l1fA:
0.0
6nknB-1l1fA:
0.0
6nknT-1l1fA:
0.0		 6nknA-1l1fA:
20.85
6nknB-1l1fA:
17.89
6nknT-1l1fA:
9.74