SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 9 ILE A  49
VAL A  16
ILE A  36
ILE A  56
ILE A  47
 None
 0.90A 1hshB-1l1nA:
undetectable		 1hshB-1l1nA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 11 ILE A  74
LEU A  28
ILE A  36
ILE A  90
PHE A 179
 None
 0.96A 2w9sA-1l1nA:
undetectable		 2w9sA-1l1nA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 11 ILE A  74
LEU A  28
ILE A  36
ILE A  90
PHE A 179
 None
 0.95A 2w9sB-1l1nA:
undetectable		 2w9sB-1l1nA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		4 / 6 PRO A  38
HIS A  40
LEU A 127
ALA A 172
 None
 1.32A 3gv1A-1l1nA:
0.0
3gv1C-1l1nA:
0.0		 3gv1A-1l1nA:
22.10
3gv1C-1l1nA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		4 / 6 LEU A 127
ALA A 172
PRO A  38
HIS A  40
 None
 1.34A 3gv1A-1l1nA:
0.0
3gv1B-1l1nA:
0.0		 3gv1A-1l1nA:
22.10
3gv1B-1l1nA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		3 / 3 ALA A 133
ARG A 134
LYS A 175
 None
 0.89A 3kp3B-1l1nA:
undetectable		 3kp3B-1l1nA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 9 VAL A  30
ILE A  90
ALA A 172
VAL A 150
VAL A 157
 None
 1.22A 3me6C-1l1nA:
undetectable		 3me6C-1l1nA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 9 VAL A  30
ILE A  90
ALA A 172
VAL A 150
VAL A 157
 None
 1.27A 3me6D-1l1nA:
undetectable		 3me6D-1l1nA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		4 / 8 PHE A  25
THR A  39
LYS A  22
SER A  21
 None
 1.06A 3tzfB-1l1nA:
undetectable		 3tzfB-1l1nA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 12 MET A  27
LEU A  37
GLU A  71
ILE A  47
ILE A  56
 None
 1.20A 4j24B-1l1nA:
undetectable		 4j24B-1l1nA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 1l1n GENOME POLYPROTEIN:
PICORNAIN 3C
(Enterovirus
C) 		5 / 11 GLY A 159
ALA A   7
VAL A 157
PHE A 179
ILE A  36
 None
 1.44A 4j4vD-1l1nA:
undetectable
4j4vE-1l1nA:
undetectable		 4j4vD-1l1nA:
21.88
4j4vE-1l1nA:
21.88