SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1l1s HYPOTHETICAL PROTEIN
MTH1491
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ARG A  36
ARG A  68
ARG A 103
 None
 0.91A 2jb7A-1l1sA:
undetectable
2jb7B-1l1sA:
undetectable
2jb7C-1l1sA:
undetectable		 2jb7A-1l1sA:
23.35
2jb7B-1l1sA:
23.35
2jb7C-1l1sA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1l1s HYPOTHETICAL PROTEIN
MTH1491
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ARG A  68
ARG A 103
ARG A  36
 None
 0.87A 2jb7A-1l1sA:
undetectable
2jb7B-1l1sA:
undetectable
2jb7C-1l1sA:
undetectable		 2jb7A-1l1sA:
23.35
2jb7B-1l1sA:
23.35
2jb7C-1l1sA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 1l1s HYPOTHETICAL PROTEIN
MTH1491
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ARG A 103
ARG A  36
ARG A  68
 None
 0.92A 2jb7A-1l1sA:
undetectable
2jb7B-1l1sA:
undetectable
2jb7C-1l1sA:
undetectable		 2jb7A-1l1sA:
23.35
2jb7B-1l1sA:
23.35
2jb7C-1l1sA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1l1s HYPOTHETICAL PROTEIN
MTH1491
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 PHE A   8
ILE A  37
ASP A  91
 None
 0.73A 5cswB-1l1sA:
undetectable		 5cswB-1l1sA:
17.42