SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.92A 1v55N-1l2mA:
0.0
1v55W-1l2mA:
undetectable		 1v55N-1l2mA:
10.72
1v55W-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.88A 3abkA-1l2mA:
undetectable
3abkJ-1l2mA:
undetectable		 3abkA-1l2mA:
10.72
3abkJ-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.90A 3ablN-1l2mA:
undetectable
3ablW-1l2mA:
undetectable		 3ablN-1l2mA:
10.72
3ablW-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.88A 3abmN-1l2mA:
undetectable
3abmW-1l2mA:
undetectable		 3abmN-1l2mA:
10.72
3abmW-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.89A 3asoN-1l2mA:
undetectable
3asoW-1l2mA:
undetectable		 3asoN-1l2mA:
10.72
3asoW-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 6 PHE A   7
ILE A   9
TYR A  68
PHE A  76
 None
 1.31A 4o7gB-1l2mA:
undetectable		 4o7gB-1l2mA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 7 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.87A 5b1bN-1l2mA:
undetectable
5b1bW-1l2mA:
0.0		 5b1bN-1l2mA:
10.72
5b1bW-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 7 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.86A 5b3sN-1l2mA:
undetectable
5b3sW-1l2mA:
0.0		 5b3sN-1l2mA:
10.72
5b3sW-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 7 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.86A 5iy5N-1l2mA:
0.0
5iy5W-1l2mA:
undetectable		 5iy5N-1l2mA:
10.72
5iy5W-1l2mA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.83A 5xdxN-1l2mA:
0.0
5xdxW-1l2mA:
undetectable		 5xdxN-1l2mA:
10.72
5xdxW-1l2mA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1l2m REP PROTEIN
(Tomato
yellow
leaf
curl
Sardinia
virus) 		4 / 8 ILE A   9
PHE A   7
THR A  17
LEU A  16
 None
 0.90A 5zcpN-1l2mA:
undetectable
5zcpW-1l2mA:
undetectable		 5zcpN-1l2mA:
10.72
5zcpW-1l2mA:
20.51