SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1l3a P24: PLANT
TRANSCRIPTIONAL
REGULATOR PBF-2
(Solanum
tuberosum) 		4 / 8 LYS A 100
ILE A 220
GLU A 226
ILE A  98
 None
 0.90A 2j9dJ-1l3aA:
0.0
2j9dK-1l3aA:
0.0
2j9dL-1l3aA:
0.0		 2j9dJ-1l3aA:
19.82
2j9dK-1l3aA:
19.82
2j9dL-1l3aA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1l3a P24: PLANT
TRANSCRIPTIONAL
REGULATOR PBF-2
(Solanum
tuberosum) 		4 / 7 LEU A 153
PHE A 172
ILE A 161
PHE A 203
 None
 0.84A 2opxA-1l3aA:
undetectable		 2opxA-1l3aA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1l3a P24: PLANT
TRANSCRIPTIONAL
REGULATOR PBF-2
(Solanum
tuberosum) 		4 / 8 PHE A 227
GLU A 157
LEU A 132
VAL A 130
 None
 0.88A 3ua5A-1l3aA:
undetectable		 3ua5A-1l3aA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 1l3a P24: PLANT
TRANSCRIPTIONAL
REGULATOR PBF-2
(Solanum
tuberosum) 		5 / 12 TYR A  96
VAL A 192
PHE A 134
ALA A 233
PHE A 234
 None
 1.36A 4rtbA-1l3aA:
undetectable		 4rtbA-1l3aA:
17.43