SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		3 / 3 THR A  63
PRO A  65
PRO A  18
 None
 0.90A 2d55C-1l3wA:
undetectable		 2d55C-1l3wA:
4.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		4 / 6 LEU A 189
TYR A 187
ILE A 209
GLY A 176
 None
NAG  A 801 (-4.2A)
None
None
 0.87A 2du8A-1l3wA:
undetectable		 2du8A-1l3wA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		3 / 3 ASN A  27
ILE A  24
MET A  92
 None
 0.75A 2h42C-1l3wA:
undetectable		 2h42C-1l3wA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		5 / 12 TYR A 471
LEU A 513
VAL A 511
LEU A 496
MET A 494
 None
 1.22A 3dzyD-1l3wA:
undetectable		 3dzyD-1l3wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		4 / 5 LEU A 513
ALA A 485
VAL A 525
ILE A 509
 None
 0.97A 4xe3A-1l3wA:
undetectable		 4xe3A-1l3wA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		5 / 11 PHE A 113
ASP A 111
ALA A 193
VAL A 203
VAL A 130
 None
 1.15A 4xnxA-1l3wA:
undetectable		 4xnxA-1l3wA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 1l3w EP-CADHERIN
(Xenopus
laevis) 		3 / 3 TYR A 259
ALA A 317
LEU A 242
 None
 0.68A 6d9kF-1l3wA:
undetectable		 6d9kF-1l3wA:
24.54