SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l4z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7T_A_5FWA1001_1 (SUPEROXIDE DISMUTASE [CU-ZN])	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	3 / 3	ASP B 120 LYS B 121 ASP B 122	None	0.84A	4a7tA-1l4zB: 0.0	4a7tA-1l4zB: 23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_B_DXCB1473_0 (TRANSLATION ELONGATION FACTOR SELB)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	4 / 8	ILE B 33 GLY B 24 VAL B 91 GLN B 84	None	0.84A	4acbB-1l4zB: undetectable 4acbC-1l4zB: undetectable	4acbB-1l4zB: 15.11 4acbC-1l4zB: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA506_0 (RNA POLYMERASE 3D-POL)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	3 / 3	VAL B 125 GLY B 123 LYS B 76	None	0.77A	4k50A-1l4zB: undetectable	4k50A-1l4zB: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE504_0 (RNA POLYMERASE 3D-POL)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	3 / 3	VAL B 125 GLY B 123 LYS B 76	None	0.71A	4k50E-1l4zB: undetectable	4k50E-1l4zB: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0X_B_SAMB501_1 (PEPTIDE N-METHYLTRANSFERASE)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	3 / 3	SER B 105 ALA B 104 THR B 25	None	0.67A	5n0xB-1l4zB: undetectable	5n0xB-1l4zB: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OF1_A_SALA301_1 (SPORE COAT-ASSOCIATED PROTEIN N)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	4 / 5	ALA B 107 VAL B 141 LYS B 76 ILE B 83	None	0.98A	5of1A-1l4zB: undetectable	5of1A-1l4zB: 25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	4 / 5	VAL B 13 HIS B 72 LEU B 7 ASP B 41	None	1.40A	5vcvA-1l4zB: undetectable	5vcvA-1l4zB: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H1L_A_FJQA501_0 (BIFUNCTIONAL CYTOCHROME P450/NADPH--P450 REDUCTASE)	1l4z	STREPTOKINASE (Streptococcus dysgalactiae)	5 / 10	ALA B 107 VAL B 141 VAL B 20 ALA B 82 LEU B 80	None	1.25A	6h1lA-1l4zB: undetectable	6h1lA-1l4zB: 14.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A7T_A_5FWA1001_1","SUPEROXIDE DISMUTASE [CU-ZN]","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",3,"ASP B 120;LYS B 121;ASP B 122","None","0.84A","4a7tA-1l4zB:0.0","4a7tA-1l4zB:23.23"],["4ACB_B_DXCB1473_0","TRANSLATION ELONGATION FACTOR SELB","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",4,"ILE B  33;GLY B  24;VAL B  91;GLN B  84","None","0.84A","4acbB-1l4zB:undetectable;4acbC-1l4zB:undetectable","4acbB-1l4zB:15.11;4acbC-1l4zB:15.11"],["4K50_A_ACTA506_0","RNA POLYMERASE 3D-POL","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",3,"VAL B 125;GLY B 123;LYS B  76","None","0.77A","4k50A-1l4zB:undetectable","4k50A-1l4zB:15.35"],["4K50_E_ACTE504_0","RNA POLYMERASE 3D-POL","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",3,"VAL B 125;GLY B 123;LYS B  76","None","0.71A","4k50E-1l4zB:undetectable","4k50E-1l4zB:15.35"],["5N0X_B_SAMB501_1","PEPTIDE N-METHYLTRANSFERASE","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",3,"SER B 105;ALA B 104;THR B  25","None","0.67A","5n0xB-1l4zB:undetectable","5n0xB-1l4zB:15.72"],["5OF1_A_SALA301_1","SPORE COAT-ASSOCIATED PROTEIN N","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",4,"ALA B 107;VAL B 141;LYS B  76;ILE B  83","None","0.98A","5of1A-1l4zB:undetectable","5of1A-1l4zB:25.58"],["5VCV_A_1N1A404_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",4,"VAL B  13;HIS B  72;LEU B   7;ASP B  41","None","1.40A","5vcvA-1l4zB:undetectable","5vcvA-1l4zB:18.33"],["6H1L_A_FJQA501_0","BIFUNCTIONAL CYTOCHROME P450\/NADPH--P450 REDUCTASE","1l4z","STREPTOKINASE","Streptococcus dysgalactiae",5,"ALA B 107;VAL B 141;VAL B  20;ALA B  82;LEU B  80","None","1.25A","6h1lA-1l4zB:undetectable","6h1lA-1l4zB:14.29"]]