SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.81A 1c6yB-1l5jA:
undetectable		 1c6yB-1l5jA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 1c9sA-1l5jA:
0.0
1c9sK-1l5jA:
0.0		 1c9sA-1l5jA:
7.07
1c9sK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 1c9sA-1l5jA:
0.0
1c9sB-1l5jA:
0.0		 1c9sA-1l5jA:
7.07
1c9sB-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 1c9sB-1l5jA:
0.0
1c9sC-1l5jA:
0.0		 1c9sB-1l5jA:
7.07
1c9sC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 1c9sC-1l5jA:
0.0
1c9sD-1l5jA:
0.0		 1c9sC-1l5jA:
7.07
1c9sD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 1c9sD-1l5jA:
undetectable
1c9sE-1l5jA:
0.0		 1c9sD-1l5jA:
7.07
1c9sE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 1c9sE-1l5jA:
0.0
1c9sF-1l5jA:
0.0		 1c9sE-1l5jA:
7.07
1c9sF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 1c9sF-1l5jA:
0.0
1c9sG-1l5jA:
undetectable		 1c9sF-1l5jA:
7.07
1c9sG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 1c9sG-1l5jA:
undetectable
1c9sH-1l5jA:
0.0		 1c9sG-1l5jA:
7.07
1c9sH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 1c9sH-1l5jA:
0.0
1c9sI-1l5jA:
0.0		 1c9sH-1l5jA:
7.07
1c9sI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.82A 1c9sI-1l5jA:
undetectable
1c9sJ-1l5jA:
undetectable		 1c9sI-1l5jA:
7.07
1c9sJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 1c9sJ-1l5jA:
0.0
1c9sK-1l5jA:
undetectable		 1c9sJ-1l5jA:
7.07
1c9sK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 1c9sL-1l5jA:
undetectable
1c9sM-1l5jA:
undetectable		 1c9sL-1l5jA:
7.07
1c9sM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 1c9sM-1l5jA:
undetectable
1c9sN-1l5jA:
undetectable		 1c9sM-1l5jA:
7.07
1c9sN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 1c9sN-1l5jA:
undetectable
1c9sO-1l5jA:
undetectable		 1c9sN-1l5jA:
7.07
1c9sO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 1c9sO-1l5jA:
undetectable
1c9sP-1l5jA:
undetectable		 1c9sO-1l5jA:
7.07
1c9sP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 1c9sP-1l5jA:
undetectable
1c9sQ-1l5jA:
undetectable		 1c9sP-1l5jA:
7.07
1c9sQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 1c9sQ-1l5jA:
undetectable
1c9sR-1l5jA:
undetectable		 1c9sQ-1l5jA:
7.07
1c9sR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 1c9sR-1l5jA:
undetectable
1c9sS-1l5jA:
undetectable		 1c9sR-1l5jA:
7.07
1c9sS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 1c9sS-1l5jA:
undetectable
1c9sT-1l5jA:
undetectable		 1c9sS-1l5jA:
7.07
1c9sT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 7 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 1c9sT-1l5jA:
undetectable
1c9sU-1l5jA:
undetectable		 1c9sT-1l5jA:
7.07
1c9sU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 GLY A 412
THR A 417
ILE A 479
SER A 245
 None
TRA  A 866 (-4.0A)
None
TRA  A 866 (-2.6A)
 0.81A 1c9sU-1l5jA:
undetectable
1c9sV-1l5jA:
undetectable		 1c9sU-1l5jA:
7.07
1c9sV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 1c9sL-1l5jA:
undetectable
1c9sV-1l5jA:
undetectable		 1c9sL-1l5jA:
7.07
1c9sV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLU A 582
ARG A 535
LEU A 533
ALA A 664
GLY A 381
 None
 1.38A 1cmaA-1l5jA:
undetectable
1cmaB-1l5jA:
undetectable		 1cmaA-1l5jA:
8.27
1cmaB-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 ALA A 664
GLY A 381
GLU A 582
ARG A 535
LEU A 533
 None
 1.33A 1cmcA-1l5jA:
undetectable
1cmcB-1l5jA:
undetectable		 1cmcA-1l5jA:
8.27
1cmcB-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLU A 582
ARG A 535
LEU A 533
ALA A 664
GLY A 381
 None
 1.32A 1cmcA-1l5jA:
undetectable
1cmcB-1l5jA:
undetectable		 1cmcA-1l5jA:
8.27
1cmcB-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 1d1vA-1l5jA:
0.0
1d1vB-1l5jA:
0.0		 1d1vA-1l5jA:
20.09
1d1vB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 1d1vA-1l5jA:
0.0
1d1vB-1l5jA:
0.0		 1d1vA-1l5jA:
20.09
1d1vB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 1d1wA-1l5jA:
0.0
1d1wB-1l5jA:
0.0		 1d1wA-1l5jA:
20.09
1d1wB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 1d1wA-1l5jA:
0.0
1d1wB-1l5jA:
0.0		 1d1wA-1l5jA:
20.09
1d1wB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1d1xA-1l5jA:
0.0
1d1xB-1l5jA:
0.0		 1d1xA-1l5jA:
20.09
1d1xB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 1d1xA-1l5jA:
0.0
1d1xB-1l5jA:
0.0		 1d1xA-1l5jA:
20.09
1d1xB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 1dm8A-1l5jA:
0.0
1dm8B-1l5jA:
0.0		 1dm8A-1l5jA:
20.09
1dm8B-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 1dm8A-1l5jA:
0.0
1dm8B-1l5jA:
0.0		 1dm8A-1l5jA:
20.09
1dm8B-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1dmiA-1l5jA:
0.0
1dmiB-1l5jA:
0.0		 1dmiA-1l5jA:
20.09
1dmiB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ILE A 672
PHE A 536
LEU A 579
PHE A 574
LEU A 562
 None
 1.07A 1dtlA-1l5jA:
undetectable		 1dtlA-1l5jA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 PHE A 508
PRO A 509
THR A 179
ILE A 278
SER A 575
 None
 1.29A 1fm4A-1l5jA:
0.0		 1fm4A-1l5jA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 1fopA-1l5jA:
0.0
1fopB-1l5jA:
0.0		 1fopA-1l5jA:
20.09
1fopB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.29A 1fopA-1l5jA:
0.0
1fopB-1l5jA:
0.0		 1fopA-1l5jA:
20.09
1fopB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 1gtfA-1l5jA:
0.0
1gtfK-1l5jA:
0.0		 1gtfA-1l5jA:
7.07
1gtfK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 1gtfA-1l5jA:
0.0
1gtfB-1l5jA:
0.0		 1gtfA-1l5jA:
7.07
1gtfB-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 1gtfB-1l5jA:
0.0
1gtfC-1l5jA:
0.0		 1gtfB-1l5jA:
7.07
1gtfC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 1gtfC-1l5jA:
0.0
1gtfD-1l5jA:
0.0		 1gtfC-1l5jA:
7.07
1gtfD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 1gtfD-1l5jA:
0.0
1gtfE-1l5jA:
0.0		 1gtfD-1l5jA:
7.07
1gtfE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 1gtfE-1l5jA:
0.0
1gtfF-1l5jA:
0.0		 1gtfE-1l5jA:
7.07
1gtfF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 1gtfF-1l5jA:
0.0
1gtfG-1l5jA:
0.0		 1gtfF-1l5jA:
7.07
1gtfG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 1gtfG-1l5jA:
0.0
1gtfH-1l5jA:
0.0		 1gtfG-1l5jA:
7.07
1gtfH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 1gtfH-1l5jA:
0.0
1gtfI-1l5jA:
0.0		 1gtfH-1l5jA:
7.07
1gtfI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 1gtfI-1l5jA:
0.0
1gtfJ-1l5jA:
0.0		 1gtfI-1l5jA:
7.07
1gtfJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 1gtfJ-1l5jA:
undetectable
1gtfK-1l5jA:
undetectable		 1gtfJ-1l5jA:
7.07
1gtfK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 7 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 1gtfL-1l5jA:
undetectable
1gtfM-1l5jA:
undetectable		 1gtfL-1l5jA:
7.07
1gtfM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1gtfM-1l5jA:
undetectable
1gtfN-1l5jA:
undetectable		 1gtfM-1l5jA:
7.07
1gtfN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 1gtfN-1l5jA:
undetectable
1gtfO-1l5jA:
undetectable		 1gtfN-1l5jA:
7.07
1gtfO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 1gtfO-1l5jA:
undetectable
1gtfP-1l5jA:
undetectable		 1gtfO-1l5jA:
7.07
1gtfP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1gtfP-1l5jA:
undetectable
1gtfQ-1l5jA:
undetectable		 1gtfP-1l5jA:
7.07
1gtfQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1gtfQ-1l5jA:
undetectable
1gtfR-1l5jA:
undetectable		 1gtfQ-1l5jA:
7.07
1gtfR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1gtfR-1l5jA:
undetectable
1gtfS-1l5jA:
undetectable		 1gtfR-1l5jA:
7.07
1gtfS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 1gtfS-1l5jA:
undetectable
1gtfT-1l5jA:
undetectable		 1gtfS-1l5jA:
7.07
1gtfT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1gtfT-1l5jA:
undetectable
1gtfU-1l5jA:
undetectable		 1gtfT-1l5jA:
7.07
1gtfU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1gtfU-1l5jA:
undetectable
1gtfV-1l5jA:
undetectable		 1gtfU-1l5jA:
7.07
1gtfV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.09A 1gtfL-1l5jA:
undetectable
1gtfV-1l5jA:
undetectable		 1gtfL-1l5jA:
7.07
1gtfV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 GLY A 412
THR A 417
ILE A 479
SER A 245
 None
TRA  A 866 (-4.0A)
None
TRA  A 866 (-2.6A)
 0.82A 1gtnA-1l5jA:
undetectable
1gtnK-1l5jA:
undetectable		 1gtnA-1l5jA:
7.07
1gtnK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.78A 1gtnA-1l5jA:
undetectable
1gtnB-1l5jA:
undetectable		 1gtnA-1l5jA:
7.07
1gtnB-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.19A 1gtnA-1l5jA:
undetectable
1gtnB-1l5jA:
undetectable		 1gtnA-1l5jA:
7.07
1gtnB-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 1gtnB-1l5jA:
0.0
1gtnC-1l5jA:
0.0		 1gtnB-1l5jA:
7.07
1gtnC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.80A 1gtnC-1l5jA:
undetectable
1gtnD-1l5jA:
undetectable		 1gtnC-1l5jA:
7.07
1gtnD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.81A 1gtnD-1l5jA:
undetectable
1gtnE-1l5jA:
undetectable		 1gtnD-1l5jA:
7.07
1gtnE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.78A 1gtnE-1l5jA:
undetectable
1gtnF-1l5jA:
undetectable		 1gtnE-1l5jA:
7.07
1gtnF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.82A 1gtnF-1l5jA:
undetectable
1gtnG-1l5jA:
undetectable		 1gtnF-1l5jA:
7.07
1gtnG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 1gtnG-1l5jA:
0.0
1gtnH-1l5jA:
0.0		 1gtnG-1l5jA:
7.07
1gtnH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.11A 1gtnH-1l5jA:
undetectable
1gtnI-1l5jA:
undetectable		 1gtnH-1l5jA:
7.07
1gtnI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 SER A 245
GLY A 412
THR A 417
ILE A 479
 TRA  A 866 (-2.6A)
None
TRA  A 866 (-4.0A)
None
 0.79A 1gtnJ-1l5jA:
undetectable
1gtnK-1l5jA:
undetectable		 1gtnJ-1l5jA:
7.07
1gtnK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 1gtnL-1l5jA:
undetectable
1gtnM-1l5jA:
undetectable		 1gtnL-1l5jA:
7.07
1gtnM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 1gtnM-1l5jA:
undetectable
1gtnN-1l5jA:
undetectable		 1gtnM-1l5jA:
7.07
1gtnN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 1gtnN-1l5jA:
undetectable
1gtnO-1l5jA:
undetectable		 1gtnN-1l5jA:
7.07
1gtnO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.13A 1gtnO-1l5jA:
undetectable
1gtnP-1l5jA:
undetectable		 1gtnO-1l5jA:
7.07
1gtnP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1gtnP-1l5jA:
undetectable
1gtnQ-1l5jA:
undetectable		 1gtnP-1l5jA:
7.07
1gtnQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1gtnQ-1l5jA:
undetectable
1gtnR-1l5jA:
undetectable		 1gtnQ-1l5jA:
7.07
1gtnR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 1gtnR-1l5jA:
undetectable
1gtnS-1l5jA:
undetectable		 1gtnR-1l5jA:
7.07
1gtnS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1gtnS-1l5jA:
undetectable
1gtnT-1l5jA:
undetectable		 1gtnS-1l5jA:
7.07
1gtnT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1gtnT-1l5jA:
undetectable
1gtnU-1l5jA:
undetectable		 1gtnT-1l5jA:
7.07
1gtnU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 1gtnU-1l5jA:
undetectable
1gtnV-1l5jA:
undetectable		 1gtnU-1l5jA:
7.07
1gtnV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.77A 1hshC-1l5jA:
undetectable		 1hshC-1l5jA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 1k2rA-1l5jA:
0.0
1k2rB-1l5jA:
0.0		 1k2rA-1l5jA:
19.11
1k2rB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1k2rA-1l5jA:
0.0
1k2rB-1l5jA:
0.0		 1k2rA-1l5jA:
19.11
1k2rB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 1k2sA-1l5jA:
0.0
1k2sB-1l5jA:
0.0		 1k2sA-1l5jA:
19.11
1k2sB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1k2sA-1l5jA:
0.0
1k2sB-1l5jA:
0.0		 1k2sA-1l5jA:
19.11
1k2sB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 1k2tA-1l5jA:
0.0
1k2tB-1l5jA:
0.0		 1k2tA-1l5jA:
19.11
1k2tB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1k2uA-1l5jA:
0.0
1k2uB-1l5jA:
0.0		 1k2uA-1l5jA:
19.11
1k2uB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 1lzxA-1l5jA:
0.0
1lzxB-1l5jA:
0.0		 1lzxA-1l5jA:
19.11
1lzxB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 1lzxA-1l5jA:
0.0
1lzxB-1l5jA:
0.0		 1lzxA-1l5jA:
19.11
1lzxB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1lzzA-1l5jA:
0.0
1lzzB-1l5jA:
0.0		 1lzzA-1l5jA:
19.11
1lzzB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 1lzzA-1l5jA:
0.0
1lzzB-1l5jA:
0.0		 1lzzA-1l5jA:
19.11
1lzzB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1m00A-1l5jA:
0.0
1m00B-1l5jA:
0.0		 1m00A-1l5jA:
19.11
1m00B-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 1m00A-1l5jA:
0.0
1m00B-1l5jA:
0.0		 1m00A-1l5jA:
19.11
1m00B-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ALA A 664
GLY A 381
GLU A 582
ARG A 535
LEU A 533
 None
 1.31A 1mj2A-1l5jA:
undetectable
1mj2B-1l5jA:
undetectable		 1mj2A-1l5jA:
8.51
1mj2B-1l5jA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ALA A 664
GLY A 381
GLU A 582
ARG A 535
LEU A 533
 None
 1.29A 1mjoC-1l5jA:
undetectable
1mjoD-1l5jA:
undetectable		 1mjoC-1l5jA:
8.51
1mjoD-1l5jA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLU A 582
ARG A 535
LEU A 533
ALA A 664
GLY A 381
 None
 1.31A 1mjqA-1l5jA:
undetectable
1mjqB-1l5jA:
undetectable		 1mjqA-1l5jA:
8.51
1mjqB-1l5jA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLU A 582
ARG A 535
LEU A 533
ALA A 664
GLY A 381
 None
 1.31A 1mjqC-1l5jA:
undetectable
1mjqD-1l5jA:
undetectable		 1mjqC-1l5jA:
8.51
1mjqD-1l5jA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLU A 582
ARG A 535
LEU A 533
ALA A 664
GLY A 381
 None
 1.31A 1mjqI-1l5jA:
undetectable
1mjqJ-1l5jA:
undetectable		 1mjqI-1l5jA:
8.51
1mjqJ-1l5jA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 1mmvA-1l5jA:
undetectable
1mmvB-1l5jA:
undetectable		 1mmvA-1l5jA:
19.11
1mmvB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 1mmvA-1l5jA:
undetectable
1mmvB-1l5jA:
undetectable		 1mmvA-1l5jA:
19.11
1mmvB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 1mmwA-1l5jA:
0.0
1mmwB-1l5jA:
0.0		 1mmwA-1l5jA:
19.11
1mmwB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1mmwA-1l5jA:
0.0
1mmwB-1l5jA:
0.0		 1mmwA-1l5jA:
19.11
1mmwB-1l5jA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.95A 1muiA-1l5jA:
undetectable		 1muiA-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 PHE A 536
LEU A 595
LEU A 546
 None
 0.49A 1mx1E-1l5jA:
undetectable		 1mx1E-1l5jA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 THR A 640
LEU A 641
LEU A 626
 None
 0.66A 1mz9C-1l5jA:
undetectable		 1mz9C-1l5jA:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 1nseA-1l5jA:
0.0
1nseB-1l5jA:
0.0		 1nseA-1l5jA:
20.09
1nseB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.28A 1nseA-1l5jA:
0.0
1nseB-1l5jA:
0.0		 1nseA-1l5jA:
20.09
1nseB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1nsiA-1l5jA:
undetectable
1nsiB-1l5jA:
undetectable		 1nsiA-1l5jA:
18.84
1nsiB-1l5jA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 1nsiA-1l5jA:
0.0
1nsiB-1l5jA:
0.0		 1nsiA-1l5jA:
18.84
1nsiB-1l5jA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 1nsiC-1l5jA:
0.0
1nsiD-1l5jA:
0.0		 1nsiC-1l5jA:
18.84
1nsiD-1l5jA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 1nsiC-1l5jA:
0.0
1nsiD-1l5jA:
0.0		 1nsiC-1l5jA:
18.84
1nsiD-1l5jA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 1ohrA-1l5jA:
undetectable		 1ohrA-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 1om4A-1l5jA:
0.0
1om4B-1l5jA:
0.0		 1om4A-1l5jA:
19.28
1om4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 1om4A-1l5jA:
0.0
1om4B-1l5jA:
0.0		 1om4A-1l5jA:
19.28
1om4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 1om5A-1l5jA:
0.0
1om5B-1l5jA:
0.0		 1om5A-1l5jA:
19.23
1om5B-1l5jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 159
ALA A 341
ILE A 349
PRO A 346
 None
 1.28A 1oniB-1l5jA:
undetectable
1oniC-1l5jA:
undetectable		 1oniB-1l5jA:
13.63
1oniC-1l5jA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 1p6hA-1l5jA:
0.0
1p6hB-1l5jA:
0.0		 1p6hA-1l5jA:
19.23
1p6hB-1l5jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1p6iA-1l5jA:
0.0
1p6iB-1l5jA:
0.0		 1p6iA-1l5jA:
19.23
1p6iB-1l5jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1p6iA-1l5jA:
0.0
1p6iB-1l5jA:
0.0		 1p6iA-1l5jA:
19.23
1p6iB-1l5jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1p6kA-1l5jA:
0.0
1p6kB-1l5jA:
0.0		 1p6kA-1l5jA:
19.00
1p6kB-1l5jA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1p6kA-1l5jA:
0.0
1p6kB-1l5jA:
0.0		 1p6kA-1l5jA:
19.00
1p6kB-1l5jA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 1p6lA-1l5jA:
0.0
1p6lB-1l5jA:
0.0		 1p6lA-1l5jA:
19.86
1p6lB-1l5jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 1p6lA-1l5jA:
0.0
1p6lB-1l5jA:
0.0		 1p6lA-1l5jA:
19.86
1p6lB-1l5jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 1p6mA-1l5jA:
0.0
1p6mB-1l5jA:
0.0		 1p6mA-1l5jA:
19.86
1p6mB-1l5jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1p6nA-1l5jA:
0.0
1p6nB-1l5jA:
0.0		 1p6nA-1l5jA:
19.86
1p6nB-1l5jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 1p6nA-1l5jA:
0.0
1p6nB-1l5jA:
0.0		 1p6nA-1l5jA:
19.86
1p6nB-1l5jA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1q2oA-1l5jA:
0.0
1q2oB-1l5jA:
0.0		 1q2oA-1l5jA:
19.88
1q2oB-1l5jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 1q2oA-1l5jA:
0.0
1q2oB-1l5jA:
0.0		 1q2oA-1l5jA:
19.88
1q2oB-1l5jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 CYH A 710
SER A 709
PHE A 593
LEU A 487
 F3S  A 868 (-2.2A)
F3S  A 868 (-3.3A)
None
None
 1.13A 1qcaA-1l5jA:
0.0		 1qcaA-1l5jA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.89A 1rl8A-1l5jA:
undetectable		 1rl8A-1l5jA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 1rs6A-1l5jA:
0.0
1rs6B-1l5jA:
0.0		 1rs6A-1l5jA:
19.23
1rs6B-1l5jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 1rs6A-1l5jA:
undetectable
1rs6B-1l5jA:
0.0		 1rs6A-1l5jA:
19.23
1rs6B-1l5jA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.27A 1rs8A-1l5jA:
0.0
1rs8B-1l5jA:
0.0		 1rs8A-1l5jA:
19.77
1rs8B-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 1rs8A-1l5jA:
0.0
1rs8B-1l5jA:
0.0		 1rs8A-1l5jA:
19.77
1rs8B-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 1rs9A-1l5jA:
0.0
1rs9B-1l5jA:
0.0		 1rs9A-1l5jA:
19.77
1rs9B-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.76A 1sdtB-1l5jA:
undetectable		 1sdtB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 1sduB-1l5jA:
undetectable		 1sduB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.76A 1sdvB-1l5jA:
undetectable		 1sdvB-1l5jA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 1utdA-1l5jA:
0.0
1utdB-1l5jA:
undetectable		 1utdA-1l5jA:
7.07
1utdB-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 1utdB-1l5jA:
undetectable
1utdC-1l5jA:
undetectable		 1utdB-1l5jA:
7.07
1utdC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 1utdC-1l5jA:
undetectable
1utdD-1l5jA:
0.0		 1utdC-1l5jA:
7.07
1utdD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.15A 1utdD-1l5jA:
0.0
1utdE-1l5jA:
0.0		 1utdD-1l5jA:
7.07
1utdE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 1utdE-1l5jA:
undetectable
1utdF-1l5jA:
undetectable		 1utdE-1l5jA:
7.07
1utdF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.16A 1utdF-1l5jA:
undetectable
1utdG-1l5jA:
undetectable		 1utdF-1l5jA:
7.07
1utdG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.15A 1utdG-1l5jA:
0.0
1utdH-1l5jA:
undetectable		 1utdG-1l5jA:
7.07
1utdH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 1utdH-1l5jA:
undetectable
1utdI-1l5jA:
undetectable		 1utdH-1l5jA:
7.07
1utdI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.13A 1utdJ-1l5jA:
undetectable
1utdK-1l5jA:
undetectable		 1utdJ-1l5jA:
7.07
1utdK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 1utdA-1l5jA:
0.0
1utdK-1l5jA:
0.0		 1utdA-1l5jA:
7.07
1utdK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 1utdM-1l5jA:
undetectable
1utdN-1l5jA:
undetectable		 1utdM-1l5jA:
7.07
1utdN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1utdN-1l5jA:
undetectable
1utdO-1l5jA:
undetectable		 1utdN-1l5jA:
7.07
1utdO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 1utdQ-1l5jA:
undetectable
1utdR-1l5jA:
undetectable		 1utdQ-1l5jA:
7.07
1utdR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1utdR-1l5jA:
undetectable
1utdS-1l5jA:
undetectable		 1utdR-1l5jA:
7.07
1utdS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1utdS-1l5jA:
undetectable
1utdT-1l5jA:
undetectable		 1utdS-1l5jA:
7.07
1utdT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 1utdT-1l5jA:
0.0
1utdU-1l5jA:
undetectable		 1utdT-1l5jA:
7.07
1utdU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 1utdU-1l5jA:
undetectable
1utdV-1l5jA:
undetectable		 1utdU-1l5jA:
7.07
1utdV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 1utdL-1l5jA:
undetectable
1utdV-1l5jA:
undetectable		 1utdL-1l5jA:
7.07
1utdV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 150
THR A 354
LEU A 361
MET A 147
 None
 1.09A 1uw6A-1l5jA:
undetectable
1uw6B-1l5jA:
0.0		 1uw6A-1l5jA:
12.98
1uw6B-1l5jA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 150
THR A 354
LEU A 361
MET A 147
 None
 1.10A 1uw6D-1l5jA:
undetectable
1uw6E-1l5jA:
undetectable		 1uw6D-1l5jA:
12.98
1uw6E-1l5jA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 150
THR A 354
LEU A 361
MET A 147
 None
 1.14A 1uw6P-1l5jA:
0.0
1uw6Q-1l5jA:
undetectable		 1uw6P-1l5jA:
12.98
1uw6Q-1l5jA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 LEU A 361
MET A 147
TRP A 150
THR A 354
 None
 1.03A 1uw6P-1l5jA:
0.0
1uw6T-1l5jA:
undetectable		 1uw6P-1l5jA:
12.98
1uw6T-1l5jA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 PHE A 757
ILE A 707
GLY A 708
THR A 712
LEU A 748
 None
 0.96A 1z11B-1l5jA:
0.0		 1z11B-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 1zzqA-1l5jA:
0.0
1zzqB-1l5jA:
0.0		 1zzqA-1l5jA:
18.93
1zzqB-1l5jA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 1zzqA-1l5jA:
0.0
1zzqB-1l5jA:
0.0		 1zzqA-1l5jA:
18.93
1zzqB-1l5jA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 1zzsA-1l5jA:
0.0
1zzsB-1l5jA:
0.0		 1zzsA-1l5jA:
19.88
1zzsB-1l5jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 1zzsA-1l5jA:
0.0
1zzsB-1l5jA:
0.0		 1zzsA-1l5jA:
19.88
1zzsB-1l5jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 1zztA-1l5jA:
0.0
1zztB-1l5jA:
0.0		 1zztA-1l5jA:
19.88
1zztB-1l5jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 1zztA-1l5jA:
0.0
1zztB-1l5jA:
0.0		 1zztA-1l5jA:
19.88
1zztB-1l5jA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 THR A 421
VAL A 411
GLY A 412
THR A 500
 None
 0.68A 2a1mA-1l5jA:
undetectable		 2a1mA-1l5jA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 LEU A  90
PRO A  83
ALA A  86
ILE A  87
 None
 0.87A 2aofB-1l5jA:
undetectable		 2aofB-1l5jA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 GLY A 715
PRO A 739
VAL A 737
ILE A 707
 None
 0.92A 2aoiA-1l5jA:
undetectable		 2aoiA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.87A 2aquA-1l5jA:
undetectable		 2aquA-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.85A 2aquB-1l5jA:
undetectable		 2aquB-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 2avvA-1l5jA:
undetectable		 2avvA-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.85A 2avvE-1l5jA:
undetectable		 2avvE-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ALA A 429
GLY A  95
GLY A  96
ASN A  98
 None
 0.65A 2c49B-1l5jA:
undetectable		 2c49B-1l5jA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ILE A 223
PHE A 256
ILE A  17
LEU A 199
ILE A 220
 None
 0.94A 2d0kA-1l5jA:
undetectable		 2d0kA-1l5jA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 LEU A 488
LEU A 620
PRO A 503
VAL A 589
 None
 1.05A 2dqyC-1l5jA:
0.3		 2dqyC-1l5jA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.85A 2fxeA-1l5jA:
undetectable		 2fxeA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.77A 2fxeB-1l5jA:
undetectable		 2fxeB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 2g6hA-1l5jA:
0.0
2g6hB-1l5jA:
0.0		 2g6hA-1l5jA:
19.16
2g6hB-1l5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 2g6hA-1l5jA:
0.0
2g6hB-1l5jA:
0.0		 2g6hA-1l5jA:
19.16
2g6hB-1l5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 2g6kA-1l5jA:
0.0
2g6kB-1l5jA:
0.0		 2g6kA-1l5jA:
19.16
2g6kB-1l5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 2g6kA-1l5jA:
0.0
2g6kB-1l5jA:
0.0		 2g6kA-1l5jA:
19.16
2g6kB-1l5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 2g6mA-1l5jA:
0.0
2g6mB-1l5jA:
0.0		 2g6mA-1l5jA:
19.16
2g6mB-1l5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 2g6mA-1l5jA:
0.0
2g6mB-1l5jA:
0.0		 2g6mA-1l5jA:
19.16
2g6mB-1l5jA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 2hx2A-1l5jA:
0.0
2hx2B-1l5jA:
0.0		 2hx2A-1l5jA:
19.77
2hx2B-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 2hx2A-1l5jA:
0.0
2hx2B-1l5jA:
0.0		 2hx2A-1l5jA:
19.77
2hx2B-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 2hx3A-1l5jA:
undetectable
2hx3B-1l5jA:
0.0		 2hx3A-1l5jA:
19.28
2hx3B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 2hx4A-1l5jA:
0.0
2hx4B-1l5jA:
0.0		 2hx4A-1l5jA:
19.28
2hx4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.92A 2ienA-1l5jA:
undetectable		 2ienA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.87A 2nmyA-1l5jA:
undetectable		 2nmyA-1l5jA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.85A 2nmzA-1l5jA:
undetectable		 2nmzA-1l5jA:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 733
GLY A 818
ALA A 815
LEU A 810
LEU A 735
 None
 0.98A 2npnA-1l5jA:
undetectable		 2npnA-1l5jA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 2nseA-1l5jA:
0.0
2nseB-1l5jA:
0.0		 2nseA-1l5jA:
20.09
2nseB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 2nseA-1l5jA:
0.0
2nseB-1l5jA:
0.0		 2nseA-1l5jA:
20.09
2nseB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.38A 2nsiA-1l5jA:
undetectable
2nsiB-1l5jA:
undetectable		 2nsiA-1l5jA:
18.84
2nsiB-1l5jA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.40A 2nsiA-1l5jA:
undetectable
2nsiB-1l5jA:
0.0		 2nsiA-1l5jA:
18.84
2nsiB-1l5jA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.84A 2o4kB-1l5jA:
undetectable		 2o4kB-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.76A 2o4sB-1l5jA:
undetectable		 2o4sB-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ALA A  60
PRO A  55
GLY A  56
GLU A  88
ILE A  87
 None
 1.01A 2plwA-1l5jA:
undetectable		 2plwA-1l5jA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ILE A 294
PRO A 232
GLY A 271
MET A 257
 None
 1.17A 2pnjB-1l5jA:
0.1		 2pnjB-1l5jA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.93A 2pymA-1l5jA:
undetectable		 2pymA-1l5jA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.95A 2pymB-1l5jA:
undetectable		 2pymB-1l5jA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 ARG A 485
SER A 481
TYR A 619
 None
 1.03A 2q2hA-1l5jA:
0.3
2q2hB-1l5jA:
0.6		 2q2hA-1l5jA:
10.74
2q2hB-1l5jA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.96A 2q63B-1l5jA:
undetectable		 2q63B-1l5jA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 4 LEU A  33
PRO A  37
LEU A  45
ARG A   6
 None
 1.49A 2qd2A-1l5jA:
undetectable		 2qd2A-1l5jA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.75A 2r5pD-1l5jA:
undetectable		 2r5pD-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.90A 2r5qD-1l5jA:
undetectable		 2r5qD-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 LEU A 123
HIS A 121
ALA A 153
PRO A 346
GLY A 343
 None
 1.20A 2vmyB-1l5jA:
undetectable		 2vmyB-1l5jA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3b3mA-1l5jA:
0.0
3b3mB-1l5jA:
0.0		 3b3mA-1l5jA:
19.28
3b3mB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3b3mA-1l5jA:
0.0
3b3mB-1l5jA:
0.0		 3b3mA-1l5jA:
19.28
3b3mB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3b3nA-1l5jA:
undetectable
3b3nB-1l5jA:
0.0		 3b3nA-1l5jA:
19.28
3b3nB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3b3oA-1l5jA:
0.0
3b3oB-1l5jA:
0.0		 3b3oA-1l5jA:
19.28
3b3oB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3b3pA-1l5jA:
0.0
3b3pB-1l5jA:
0.0		 3b3pA-1l5jA:
19.28
3b3pB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 SER A 603
GLY A 243
GLY A 241
 None
 0.50A 3bogA-1l5jA:
undetectable
3bogC-1l5jA:
undetectable		 3bogA-1l5jA:
undetectable
3bogC-1l5jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.89A 3bvbA-1l5jA:
undetectable		 3bvbA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.83A 3bvbB-1l5jA:
undetectable		 3bvbB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.80A 3cfqA-1l5jA:
undetectable
3cfqB-1l5jA:
undetectable		 3cfqA-1l5jA:
7.50
3cfqB-1l5jA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ARG A 791
ASN A 775
ALA A 188
ASP A 497
THR A 285
 TRA  A 866 (-3.6A)
None
None
TRA  A 866 (-3.5A)
None
 1.14A 3ckkA-1l5jA:
undetectable		 3ckkA-1l5jA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.86A 3d1xA-1l5jA:
undetectable		 3d1xA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.79A 3d1yA-1l5jA:
undetectable		 3d1yA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3dqsA-1l5jA:
0.0
3dqsB-1l5jA:
0.0		 3dqsA-1l5jA:
19.77
3dqsB-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3dqsA-1l5jA:
0.0
3dqsB-1l5jA:
0.0		 3dqsA-1l5jA:
19.77
3dqsB-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3dqtA-1l5jA:
0.0
3dqtB-1l5jA:
0.0		 3dqtA-1l5jA:
19.77
3dqtB-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3dqtA-1l5jA:
undetectable
3dqtB-1l5jA:
4.1		 3dqtA-1l5jA:
19.77
3dqtB-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.37A 3e7gA-1l5jA:
undetectable
3e7gB-1l5jA:
undetectable		 3e7gA-1l5jA:
19.43
3e7gB-1l5jA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3e7gA-1l5jA:
undetectable
3e7gB-1l5jA:
undetectable		 3e7gA-1l5jA:
19.43
3e7gB-1l5jA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3e7gC-1l5jA:
0.0
3e7gD-1l5jA:
0.0		 3e7gC-1l5jA:
19.43
3e7gD-1l5jA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.95A 3ekpA-1l5jA:
undetectable		 3ekpA-1l5jA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.85A 3ekqA-1l5jA:
undetectable		 3ekqA-1l5jA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.83A 3ekwB-1l5jA:
undetectable		 3ekwB-1l5jA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.88A 3ekxA-1l5jA:
undetectable		 3ekxA-1l5jA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.85A 3ekyA-1l5jA:
undetectable		 3ekyA-1l5jA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.87A 3el1B-1l5jA:
undetectable		 3el1B-1l5jA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3fc5A-1l5jA:
0.0
3fc5B-1l5jA:
0.0		 3fc5A-1l5jA:
19.28
3fc5B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3fc5A-1l5jA:
0.0
3fc5B-1l5jA:
0.0		 3fc5A-1l5jA:
19.28
3fc5B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 342
GLY A 290
ILE A 261
LEU A 347
GLN A  94
 None
 0.90A 3fzgA-1l5jA:
undetectable		 3fzgA-1l5jA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ALA A 510
GLY A 496
ASP A 288
SER A 507
GLY A 493
 None
 0.92A 3g2oB-1l5jA:
2.6		 3g2oB-1l5jA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3hsnA-1l5jA:
undetectable
3hsnB-1l5jA:
undetectable		 3hsnA-1l5jA:
19.28
3hsnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3hsnA-1l5jA:
undetectable
3hsnB-1l5jA:
undetectable		 3hsnA-1l5jA:
19.28
3hsnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3hsoA-1l5jA:
undetectable
3hsoB-1l5jA:
undetectable		 3hsoA-1l5jA:
19.28
3hsoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3hsoA-1l5jA:
0.0
3hsoB-1l5jA:
0.0		 3hsoA-1l5jA:
19.28
3hsoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3hspA-1l5jA:
0.0
3hspB-1l5jA:
0.0		 3hspA-1l5jA:
19.28
3hspB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3hspA-1l5jA:
0.0
3hspB-1l5jA:
0.0		 3hspA-1l5jA:
19.28
3hspB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3jt3A-1l5jA:
0.0
3jt3B-1l5jA:
0.0		 3jt3A-1l5jA:
19.28
3jt3B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3jt3A-1l5jA:
0.0
3jt3B-1l5jA:
0.0		 3jt3A-1l5jA:
19.28
3jt3B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3jt4A-1l5jA:
0.0
3jt4B-1l5jA:
0.0		 3jt4A-1l5jA:
19.28
3jt4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.29A 3jt4A-1l5jA:
0.0
3jt4B-1l5jA:
0.0		 3jt4A-1l5jA:
19.28
3jt4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 3jt5A-1l5jA:
0.0
3jt5B-1l5jA:
0.0		 3jt5A-1l5jA:
19.28
3jt5B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3jt5A-1l5jA:
0.0
3jt5B-1l5jA:
0.0		 3jt5A-1l5jA:
19.28
3jt5B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3jt6A-1l5jA:
0.0
3jt6B-1l5jA:
0.0		 3jt6A-1l5jA:
19.28
3jt6B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3jt6A-1l5jA:
0.0
3jt6B-1l5jA:
0.0		 3jt6A-1l5jA:
19.28
3jt6B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3jt7A-1l5jA:
0.0
3jt7B-1l5jA:
0.0		 3jt7A-1l5jA:
19.28
3jt7B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3jt7A-1l5jA:
0.0
3jt7B-1l5jA:
0.0		 3jt7A-1l5jA:
19.28
3jt7B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jt8A-1l5jA:
0.0
3jt8B-1l5jA:
0.0		 3jt8A-1l5jA:
19.28
3jt8B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3jt8A-1l5jA:
0.0
3jt8B-1l5jA:
0.0		 3jt8A-1l5jA:
19.28
3jt8B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jt9A-1l5jA:
0.0
3jt9B-1l5jA:
0.0		 3jt9A-1l5jA:
19.28
3jt9B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 3jt9A-1l5jA:
0.0
3jt9B-1l5jA:
0.0		 3jt9A-1l5jA:
19.28
3jt9B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jtaA-1l5jA:
0.0
3jtaB-1l5jA:
0.0		 3jtaA-1l5jA:
19.28
3jtaB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 3jtaA-1l5jA:
0.0
3jtaB-1l5jA:
0.0		 3jtaA-1l5jA:
19.28
3jtaB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.90A 3jw2A-1l5jA:
undetectable		 3jw2A-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3jwsA-1l5jA:
0.0
3jwsB-1l5jA:
0.0		 3jwsA-1l5jA:
19.31
3jwsB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3jwsA-1l5jA:
0.0
3jwsB-1l5jA:
0.0		 3jwsA-1l5jA:
19.31
3jwsB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3jwtA-1l5jA:
0.0
3jwtB-1l5jA:
0.0		 3jwtA-1l5jA:
19.31
3jwtB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3jwtA-1l5jA:
0.0
3jwtB-1l5jA:
0.0		 3jwtA-1l5jA:
19.31
3jwtB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jwuA-1l5jA:
0.0
3jwuB-1l5jA:
0.0		 3jwuA-1l5jA:
19.31
3jwuB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3jwuA-1l5jA:
0.0
3jwuB-1l5jA:
0.0		 3jwuA-1l5jA:
19.31
3jwuB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jwvA-1l5jA:
0.0
3jwvB-1l5jA:
0.0		 3jwvA-1l5jA:
19.31
3jwvB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3jwvA-1l5jA:
0.0
3jwvB-1l5jA:
0.0		 3jwvA-1l5jA:
19.31
3jwvB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3jwxA-1l5jA:
0.0
3jwxB-1l5jA:
0.0		 3jwxA-1l5jA:
20.09
3jwxB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3jwxA-1l5jA:
0.0
3jwxB-1l5jA:
0.0		 3jwxA-1l5jA:
20.09
3jwxB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3jwyA-1l5jA:
0.0
3jwyB-1l5jA:
0.0		 3jwyA-1l5jA:
20.09
3jwyB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 3jwyA-1l5jA:
0.0
3jwyB-1l5jA:
0.0		 3jwyA-1l5jA:
20.09
3jwyB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jwzA-1l5jA:
0.0
3jwzB-1l5jA:
0.0		 3jwzA-1l5jA:
20.09
3jwzB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 3jwzA-1l5jA:
0.0
3jwzB-1l5jA:
0.0		 3jwzA-1l5jA:
20.09
3jwzB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jx0A-1l5jA:
0.0
3jx0B-1l5jA:
0.0		 3jx0A-1l5jA:
19.05
3jx0B-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3jx0A-1l5jA:
0.0
3jx0B-1l5jA:
0.0		 3jx0A-1l5jA:
19.05
3jx0B-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3jx1A-1l5jA:
0.0
3jx1B-1l5jA:
0.0		 3jx1A-1l5jA:
19.05
3jx1B-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3jx1A-1l5jA:
undetectable
3jx1B-1l5jA:
undetectable		 3jx1A-1l5jA:
19.05
3jx1B-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 ASN A 284
ASP A 527
ARG A 159
 None
 0.94A 3k13C-1l5jA:
undetectable		 3k13C-1l5jA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.80A 3k4vA-1l5jA:
undetectable		 3k4vA-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.83A 3k4vB-1l5jA:
undetectable		 3k4vB-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.86A 3k4vD-1l5jA:
undetectable		 3k4vD-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.89A 3lzuB-1l5jA:
undetectable		 3lzuB-1l5jA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 3n2rA-1l5jA:
0.0
3n2rB-1l5jA:
0.0		 3n2rA-1l5jA:
19.28
3n2rB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3n2rA-1l5jA:
0.0
3n2rB-1l5jA:
0.0		 3n2rA-1l5jA:
19.28
3n2rB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 3n5rA-1l5jA:
0.0
3n5rB-1l5jA:
0.0		 3n5rA-1l5jA:
20.09
3n5rB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 3n5rA-1l5jA:
0.0
3n5rB-1l5jA:
0.0		 3n5rA-1l5jA:
20.09
3n5rB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3n5sA-1l5jA:
0.0
3n5sB-1l5jA:
0.0		 3n5sA-1l5jA:
20.09
3n5sB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 3n5sA-1l5jA:
0.0
3n5sB-1l5jA:
0.0		 3n5sA-1l5jA:
20.09
3n5sB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3n5tA-1l5jA:
0.0
3n5tB-1l5jA:
undetectable		 3n5tA-1l5jA:
20.09
3n5tB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 3n5tA-1l5jA:
0.0
3n5tB-1l5jA:
0.0		 3n5tA-1l5jA:
20.09
3n5tB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.27A 3n5vA-1l5jA:
0.0
3n5vB-1l5jA:
0.0		 3n5vA-1l5jA:
19.28
3n5vB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3n5vA-1l5jA:
0.0
3n5vB-1l5jA:
0.0		 3n5vA-1l5jA:
19.28
3n5vB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 3n5yA-1l5jA:
0.0
3n5yB-1l5jA:
0.0		 3n5yA-1l5jA:
19.28
3n5yB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3n5yA-1l5jA:
0.0
3n5yB-1l5jA:
0.0		 3n5yA-1l5jA:
19.28
3n5yB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 3n5zA-1l5jA:
undetectable
3n5zB-1l5jA:
undetectable		 3n5zA-1l5jA:
19.28
3n5zB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3n5zA-1l5jA:
0.0
3n5zB-1l5jA:
0.0		 3n5zA-1l5jA:
19.28
3n5zB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3n67A-1l5jA:
0.0
3n67B-1l5jA:
0.0		 3n67A-1l5jA:
19.75
3n67B-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3n67A-1l5jA:
0.0
3n67B-1l5jA:
0.0		 3n67A-1l5jA:
19.75
3n67B-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N68_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3n68A-1l5jA:
0.0
3n68B-1l5jA:
0.0		 3n68A-1l5jA:
19.75
3n68B-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N68_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3n68A-1l5jA:
0.0
3n68B-1l5jA:
0.0		 3n68A-1l5jA:
19.75
3n68B-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3n69A-1l5jA:
0.0
3n69B-1l5jA:
0.0		 3n69A-1l5jA:
19.75
3n69B-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3n69A-1l5jA:
0.0
3n69B-1l5jA:
0.0		 3n69A-1l5jA:
19.75
3n69B-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3n6aA-1l5jA:
0.0
3n6aB-1l5jA:
0.0		 3n6aA-1l5jA:
19.75
3n6aB-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3n6aA-1l5jA:
0.0
3n6aB-1l5jA:
0.0		 3n6aA-1l5jA:
19.75
3n6aB-1l5jA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3n6eA-1l5jA:
0.0
3n6eB-1l5jA:
0.0		 3n6eA-1l5jA:
20.09
3n6eB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3n6eA-1l5jA:
0.0
3n6eB-1l5jA:
0.0		 3n6eA-1l5jA:
20.09
3n6eB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3n6fA-1l5jA:
0.0
3n6fB-1l5jA:
0.0		 3n6fA-1l5jA:
20.09
3n6fB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3n6fA-1l5jA:
0.0
3n6fB-1l5jA:
0.0		 3n6fA-1l5jA:
20.09
3n6fB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3n6gA-1l5jA:
0.0
3n6gB-1l5jA:
0.0		 3n6gA-1l5jA:
20.09
3n6gB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3n6gA-1l5jA:
0.0
3n6gB-1l5jA:
0.0		 3n6gA-1l5jA:
20.09
3n6gB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.77A 3ndtB-1l5jA:
undetectable		 3ndtB-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.86A 3ndtD-1l5jA:
undetectable		 3ndtD-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.84A 3nduA-1l5jA:
undetectable		 3nduA-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.79A 3nduD-1l5jA:
undetectable		 3nduD-1l5jA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 3ndxB-1l5jA:
undetectable		 3ndxB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3nleA-1l5jA:
0.0
3nleB-1l5jA:
0.0		 3nleA-1l5jA:
20.09
3nleB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3nleA-1l5jA:
0.0
3nleB-1l5jA:
0.0		 3nleA-1l5jA:
20.09
3nleB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 3nlfA-1l5jA:
0.0
3nlfB-1l5jA:
0.0		 3nlfA-1l5jA:
20.09
3nlfB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 3nlgA-1l5jA:
0.0
3nlgB-1l5jA:
0.0		 3nlgA-1l5jA:
20.09
3nlgB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3nlgA-1l5jA:
0.0
3nlgB-1l5jA:
0.0		 3nlgA-1l5jA:
20.09
3nlgB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3nlhA-1l5jA:
0.0
3nlhB-1l5jA:
0.0		 3nlhA-1l5jA:
20.09
3nlhB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3nlhA-1l5jA:
0.0
3nlhB-1l5jA:
0.0		 3nlhA-1l5jA:
20.09
3nlhB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3nliA-1l5jA:
0.0
3nliB-1l5jA:
0.0		 3nliA-1l5jA:
20.09
3nliB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3nliA-1l5jA:
0.0
3nliB-1l5jA:
0.0		 3nliA-1l5jA:
20.09
3nliB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.38A 3nlkA-1l5jA:
undetectable
3nlkB-1l5jA:
undetectable		 3nlkA-1l5jA:
19.31
3nlkB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3nlmA-1l5jA:
0.0
3nlmB-1l5jA:
0.0		 3nlmA-1l5jA:
19.28
3nlmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3nlmA-1l5jA:
0.0
3nlmB-1l5jA:
0.0		 3nlmA-1l5jA:
19.28
3nlmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3nlnA-1l5jA:
0.0
3nlnB-1l5jA:
0.0		 3nlnA-1l5jA:
19.31
3nlnB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3nlnA-1l5jA:
0.0
3nlnB-1l5jA:
0.0		 3nlnA-1l5jA:
19.31
3nlnB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3nloA-1l5jA:
0.0
3nloB-1l5jA:
0.0		 3nloA-1l5jA:
19.31
3nloB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3nloA-1l5jA:
0.0
3nloB-1l5jA:
0.0		 3nloA-1l5jA:
19.31
3nloB-1l5jA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3nluA-1l5jA:
0.0
3nluB-1l5jA:
0.0		 3nluA-1l5jA:
20.09
3nluB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3nluA-1l5jA:
0.0
3nluB-1l5jA:
0.0		 3nluA-1l5jA:
20.09
3nluB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3nlvA-1l5jA:
0.0
3nlvB-1l5jA:
0.0		 3nlvA-1l5jA:
19.28
3nlvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3nlvA-1l5jA:
0.0
3nlvB-1l5jA:
0.0		 3nlvA-1l5jA:
19.28
3nlvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3nlwA-1l5jA:
0.0
3nlwB-1l5jA:
0.0		 3nlwA-1l5jA:
19.28
3nlwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3nlwA-1l5jA:
0.0
3nlwB-1l5jA:
0.0		 3nlwA-1l5jA:
19.28
3nlwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3nlxA-1l5jA:
0.0
3nlxB-1l5jA:
0.0		 3nlxA-1l5jA:
19.28
3nlxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3nlxA-1l5jA:
0.0
3nlxB-1l5jA:
0.0		 3nlxA-1l5jA:
19.28
3nlxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3nlyA-1l5jA:
undetectable
3nlyB-1l5jA:
0.0		 3nlyA-1l5jA:
19.28
3nlyB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3nlzA-1l5jA:
0.0
3nlzB-1l5jA:
0.0		 3nlzA-1l5jA:
19.28
3nlzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3nlzA-1l5jA:
0.0
3nlzB-1l5jA:
0.0		 3nlzA-1l5jA:
19.28
3nlzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3nm0A-1l5jA:
0.0
3nm0B-1l5jA:
0.0		 3nm0A-1l5jA:
19.28
3nm0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3nm0A-1l5jA:
0.0
3nm0B-1l5jA:
0.0		 3nm0A-1l5jA:
19.28
3nm0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3nnyA-1l5jA:
0.0
3nnyB-1l5jA:
0.0		 3nnyA-1l5jA:
19.28
3nnyB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3nnyA-1l5jA:
0.0
3nnyB-1l5jA:
0.0		 3nnyA-1l5jA:
19.28
3nnyB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3nnzA-1l5jA:
0.0
3nnzB-1l5jA:
0.0		 3nnzA-1l5jA:
19.28
3nnzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3nnzA-1l5jA:
0.0
3nnzB-1l5jA:
0.0		 3nnzA-1l5jA:
19.28
3nnzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.76A 3nu3B-1l5jA:
undetectable		 3nu3B-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 3nu4B-1l5jA:
undetectable		 3nu4B-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.83A 3nujB-1l5jA:
undetectable		 3nujB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.80A 3nuoB-1l5jA:
undetectable		 3nuoB-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3pneA-1l5jA:
0.0
3pneB-1l5jA:
0.0		 3pneA-1l5jA:
19.28
3pneB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3pneA-1l5jA:
0.0
3pneB-1l5jA:
0.0		 3pneA-1l5jA:
19.28
3pneB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3pnfA-1l5jA:
0.0
3pnfB-1l5jA:
0.0		 3pnfA-1l5jA:
19.28
3pnfB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3pnfA-1l5jA:
0.0
3pnfB-1l5jA:
0.0		 3pnfA-1l5jA:
19.28
3pnfB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3pngA-1l5jA:
0.0
3pngB-1l5jA:
0.0		 3pngA-1l5jA:
19.28
3pngB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3pngA-1l5jA:
0.0
3pngB-1l5jA:
0.0		 3pngA-1l5jA:
19.28
3pngB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3pnhA-1l5jA:
0.0
3pnhB-1l5jA:
0.0		 3pnhA-1l5jA:
19.77
3pnhB-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3pnhA-1l5jA:
0.0
3pnhB-1l5jA:
0.0		 3pnhA-1l5jA:
19.77
3pnhB-1l5jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.88A 3pwrA-1l5jA:
undetectable		 3pwrA-1l5jA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3q99A-1l5jA:
0.0
3q99B-1l5jA:
0.0		 3q99A-1l5jA:
19.28
3q99B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 3q99A-1l5jA:
0.0
3q99B-1l5jA:
0.0		 3q99A-1l5jA:
19.28
3q99B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 3q9aA-1l5jA:
0.0
3q9aB-1l5jA:
0.0		 3q9aA-1l5jA:
19.28
3q9aB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3q9aA-1l5jA:
0.0
3q9aB-1l5jA:
0.0		 3q9aA-1l5jA:
19.28
3q9aB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3rqjA-1l5jA:
0.0
3rqjB-1l5jA:
0.0		 3rqjA-1l5jA:
19.28
3rqjB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3rqjA-1l5jA:
undetectable
3rqjB-1l5jA:
0.0		 3rqjA-1l5jA:
19.28
3rqjB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.38A 3rqkA-1l5jA:
0.0
3rqkB-1l5jA:
0.0		 3rqkA-1l5jA:
19.28
3rqkB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3rqlA-1l5jA:
0.0
3rqlB-1l5jA:
0.0		 3rqlA-1l5jA:
19.28
3rqlB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3rqlA-1l5jA:
3.7
3rqlB-1l5jA:
0.0		 3rqlA-1l5jA:
19.28
3rqlB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 3rqmA-1l5jA:
0.0
3rqmB-1l5jA:
0.0		 3rqmA-1l5jA:
19.28
3rqmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3rqmA-1l5jA:
0.0
3rqmB-1l5jA:
0.0		 3rqmA-1l5jA:
19.28
3rqmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3rqnA-1l5jA:
0.0
3rqnB-1l5jA:
0.0		 3rqnA-1l5jA:
19.28
3rqnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 3rqnA-1l5jA:
3.7
3rqnB-1l5jA:
0.0		 3rqnA-1l5jA:
19.28
3rqnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 3rqoA-1l5jA:
0.0
3rqoB-1l5jA:
0.0		 3rqoA-1l5jA:
20.21
3rqoB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3rqoA-1l5jA:
0.0
3rqoB-1l5jA:
0.0		 3rqoA-1l5jA:
20.21
3rqoB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3rqpA-1l5jA:
0.0
3rqpB-1l5jA:
0.0		 3rqpA-1l5jA:
20.21
3rqpB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 TYR A 843
ASN A 713
ILE A 714
ALA A 808
THR A 788
 None
 1.12A 3rukD-1l5jA:
undetectable		 3rukD-1l5jA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 3s43B-1l5jA:
undetectable		 3s43B-1l5jA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.87A 3s54A-1l5jA:
undetectable		 3s54A-1l5jA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 418
LEU A 514
GLY A 511
ALA A 519
ALA A 518
 None
 1.06A 3sufA-1l5jA:
undetectable		 3sufA-1l5jA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3svqA-1l5jA:
0.0
3svqB-1l5jA:
0.0		 3svqA-1l5jA:
19.28
3svqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 PHE A 757
PHE A 717
THR A 788
LEU A 735
 None
 1.13A 3t3zC-1l5jA:
0.0		 3t3zC-1l5jA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 LEU A 124
GLY A 432
ALA A 520
PHE A 433
 None
 1.01A 3tehB-1l5jA:
undetectable		 3tehB-1l5jA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.82A 3tkgC-1l5jA:
undetectable		 3tkgC-1l5jA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.88A 3tkwB-1l5jA:
undetectable		 3tkwB-1l5jA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.86A 3tl9A-1l5jA:
undetectable		 3tl9A-1l5jA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.83A 3tl9B-1l5jA:
undetectable		 3tl9B-1l5jA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3tylA-1l5jA:
0.0
3tylB-1l5jA:
0.0		 3tylA-1l5jA:
19.28
3tylB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3tylA-1l5jA:
0.0
3tylB-1l5jA:
0.0		 3tylA-1l5jA:
19.28
3tylB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3tymA-1l5jA:
undetectable
3tymB-1l5jA:
undetectable		 3tymA-1l5jA:
19.28
3tymB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3tymA-1l5jA:
0.0
3tymB-1l5jA:
0.0		 3tymA-1l5jA:
19.28
3tymB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 3tynA-1l5jA:
undetectable
3tynB-1l5jA:
undetectable		 3tynA-1l5jA:
19.28
3tynB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3tynA-1l5jA:
0.0
3tynB-1l5jA:
0.0		 3tynA-1l5jA:
19.28
3tynB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3tyoA-1l5jA:
0.0
3tyoB-1l5jA:
0.0		 3tyoA-1l5jA:
19.28
3tyoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 3tyoA-1l5jA:
undetectable
3tyoB-1l5jA:
undetectable		 3tyoA-1l5jA:
19.28
3tyoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 3ufoA-1l5jA:
undetectable
3ufoB-1l5jA:
undetectable		 3ufoA-1l5jA:
19.28
3ufoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3ufoA-1l5jA:
0.0
3ufoB-1l5jA:
0.0		 3ufoA-1l5jA:
19.28
3ufoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 3ufpA-1l5jA:
undetectable
3ufpB-1l5jA:
3.6		 3ufpA-1l5jA:
19.28
3ufpB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3ufqA-1l5jA:
0.0
3ufqB-1l5jA:
0.0		 3ufqA-1l5jA:
19.28
3ufqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.48A 3ufrA-1l5jA:
0.0
3ufrB-1l5jA:
0.0		 3ufrA-1l5jA:
19.28
3ufrB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 3ufsA-1l5jA:
0.0
3ufsB-1l5jA:
0.0		 3ufsA-1l5jA:
19.28
3ufsB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 3ufuA-1l5jA:
0.0
3ufuB-1l5jA:
0.0		 3ufuA-1l5jA:
19.28
3ufuB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 3ufuA-1l5jA:
0.0
3ufuB-1l5jA:
0.0		 3ufuA-1l5jA:
19.28
3ufuB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 3ufvA-1l5jA:
0.0
3ufvB-1l5jA:
0.0		 3ufvA-1l5jA:
19.28
3ufvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 3ufvA-1l5jA:
0.0
3ufvB-1l5jA:
0.0		 3ufvA-1l5jA:
19.28
3ufvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 3ufwA-1l5jA:
0.0
3ufwB-1l5jA:
0.0		 3ufwA-1l5jA:
19.28
3ufwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.40A 3ufwA-1l5jA:
0.0
3ufwB-1l5jA:
0.0		 3ufwA-1l5jA:
19.28
3ufwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 GLY A 495
GLY A 412
GLY A 418
ILE A 464
LEU A 460
 None
 1.41A 3v1nA-1l5jA:
undetectable		 3v1nA-1l5jA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 PRO A 219
ASP A 212
GLU A 210
 None
 0.75A 3v4tC-1l5jA:
0.0		 3v4tC-1l5jA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 THR A 445
CYH A 769
GLY A 768
ILE A 479
 None
F3S  A 868 (-2.2A)
None
None
 1.02A 3w9tF-1l5jA:
0.0		 3w9tF-1l5jA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 PHE A 433
LEU A 460
GLY A 418
VAL A 515
 None
 0.94A 3wrkD-1l5jA:
undetectable		 3wrkD-1l5jA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4c39A-1l5jA:
0.0
4c39B-1l5jA:
0.0		 4c39A-1l5jA:
19.28
4c39B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4c39A-1l5jA:
0.0
4c39B-1l5jA:
0.0		 4c39A-1l5jA:
19.28
4c39B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4c3aA-1l5jA:
0.0
4c3aB-1l5jA:
0.0		 4c3aA-1l5jA:
20.21
4c3aB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4c3aA-1l5jA:
0.0
4c3aB-1l5jA:
0.0		 4c3aA-1l5jA:
20.21
4c3aB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4camA-1l5jA:
0.0
4camB-1l5jA:
0.0		 4camA-1l5jA:
19.28
4camB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4camA-1l5jA:
0.0
4camB-1l5jA:
0.0		 4camA-1l5jA:
19.28
4camB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4canA-1l5jA:
0.0
4canB-1l5jA:
0.0		 4canA-1l5jA:
19.28
4canB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4caqA-1l5jA:
0.0
4caqB-1l5jA:
0.0		 4caqA-1l5jA:
19.28
4caqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4carA-1l5jA:
0.0
4carB-1l5jA:
0.0		 4carA-1l5jA:
20.21
4carB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4carA-1l5jA:
0.0
4carB-1l5jA:
0.0		 4carA-1l5jA:
20.21
4carB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 4cftA-1l5jA:
0.0
4cftB-1l5jA:
0.0		 4cftA-1l5jA:
20.21
4cftB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4cftA-1l5jA:
0.0
4cftB-1l5jA:
0.0		 4cftA-1l5jA:
20.21
4cftB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4ctpA-1l5jA:
0.0
4ctpB-1l5jA:
0.0		 4ctpA-1l5jA:
19.28
4ctpB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4ctpA-1l5jA:
0.0
4ctpB-1l5jA:
0.0		 4ctpA-1l5jA:
19.28
4ctpB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4ctqA-1l5jA:
0.0
4ctqB-1l5jA:
0.0		 4ctqA-1l5jA:
19.28
4ctqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4ctqA-1l5jA:
0.0
4ctqB-1l5jA:
0.0		 4ctqA-1l5jA:
19.28
4ctqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 4ctrA-1l5jA:
0.0
4ctrB-1l5jA:
0.0		 4ctrA-1l5jA:
19.28
4ctrB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 4cttA-1l5jA:
0.0
4cttB-1l5jA:
0.0		 4cttA-1l5jA:
19.28
4cttB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4ctuA-1l5jA:
0.0
4ctuB-1l5jA:
0.0		 4ctuA-1l5jA:
19.28
4ctuB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4ctuA-1l5jA:
0.0
4ctuB-1l5jA:
0.0		 4ctuA-1l5jA:
19.28
4ctuB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4ctvA-1l5jA:
0.0
4ctvB-1l5jA:
0.0		 4ctvA-1l5jA:
19.28
4ctvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4ctvA-1l5jA:
0.0
4ctvB-1l5jA:
0.0		 4ctvA-1l5jA:
19.28
4ctvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4ctwA-1l5jA:
0.0
4ctwB-1l5jA:
0.0		 4ctwA-1l5jA:
19.28
4ctwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4ctwA-1l5jA:
0.0
4ctwB-1l5jA:
0.0		 4ctwA-1l5jA:
19.28
4ctwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4ctxA-1l5jA:
0.0
4ctxB-1l5jA:
0.0		 4ctxA-1l5jA:
19.28
4ctxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4ctxA-1l5jA:
0.0
4ctxB-1l5jA:
0.0		 4ctxA-1l5jA:
19.28
4ctxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4ctyA-1l5jA:
0.0
4ctyB-1l5jA:
0.0		 4ctyA-1l5jA:
20.21
4ctyB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4ctyA-1l5jA:
0.0
4ctyB-1l5jA:
0.0		 4ctyA-1l5jA:
20.21
4ctyB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4cu0A-1l5jA:
0.2
4cu0B-1l5jA:
0.0		 4cu0A-1l5jA:
20.21
4cu0B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4cu0A-1l5jA:
0.2
4cu0B-1l5jA:
0.0		 4cu0A-1l5jA:
20.21
4cu0B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4cu1A-1l5jA:
0.0
4cu1B-1l5jA:
0.0		 4cu1A-1l5jA:
20.21
4cu1B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4cu1A-1l5jA:
0.0
4cu1B-1l5jA:
0.0		 4cu1A-1l5jA:
20.21
4cu1B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4cwvA-1l5jA:
0.0
4cwvB-1l5jA:
0.0		 4cwvA-1l5jA:
20.21
4cwvB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4cwvA-1l5jA:
0.0
4cwvB-1l5jA:
0.0		 4cwvA-1l5jA:
20.21
4cwvB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4cwwA-1l5jA:
0.0
4cwwB-1l5jA:
0.0		 4cwwA-1l5jA:
20.21
4cwwB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4cwwA-1l5jA:
0.0
4cwwB-1l5jA:
0.0		 4cwwA-1l5jA:
20.21
4cwwB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 4cwxA-1l5jA:
0.0
4cwxB-1l5jA:
0.0		 4cwxA-1l5jA:
20.21
4cwxB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4cwxA-1l5jA:
0.0
4cwxB-1l5jA:
0.0		 4cwxA-1l5jA:
20.21
4cwxB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4cwyA-1l5jA:
0.0
4cwyB-1l5jA:
0.0		 4cwyA-1l5jA:
20.21
4cwyB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4cwyA-1l5jA:
0.0
4cwyB-1l5jA:
0.0		 4cwyA-1l5jA:
20.21
4cwyB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4cwzA-1l5jA:
0.0
4cwzB-1l5jA:
0.0		 4cwzA-1l5jA:
19.98
4cwzB-1l5jA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4cwzA-1l5jA:
0.0
4cwzB-1l5jA:
0.0		 4cwzA-1l5jA:
19.98
4cwzB-1l5jA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4cx0A-1l5jA:
0.0
4cx0B-1l5jA:
0.0		 4cx0A-1l5jA:
19.98
4cx0B-1l5jA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4cx0A-1l5jA:
0.0
4cx0B-1l5jA:
0.0		 4cx0A-1l5jA:
19.98
4cx0B-1l5jA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4cx5A-1l5jA:
undetectable
4cx5B-1l5jA:
0.0		 4cx5A-1l5jA:
18.95
4cx5B-1l5jA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4cx5A-1l5jA:
0.0
4cx5B-1l5jA:
0.0		 4cx5A-1l5jA:
18.95
4cx5B-1l5jA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4cx6A-1l5jA:
0.0
4cx6B-1l5jA:
0.0		 4cx6A-1l5jA:
18.95
4cx6B-1l5jA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4cx6A-1l5jA:
0.0
4cx6B-1l5jA:
0.0		 4cx6A-1l5jA:
18.95
4cx6B-1l5jA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 4d1nA-1l5jA:
0.0
4d1nB-1l5jA:
0.0		 4d1nA-1l5jA:
20.19
4d1nB-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4d1nA-1l5jA:
0.0
4d1nB-1l5jA:
0.0		 4d1nA-1l5jA:
20.19
4d1nB-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 4d1nC-1l5jA:
0.0
4d1nD-1l5jA:
0.0		 4d1nC-1l5jA:
20.19
4d1nD-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.28A 4d1nC-1l5jA:
0.0
4d1nD-1l5jA:
0.0		 4d1nC-1l5jA:
20.19
4d1nD-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4d1oA-1l5jA:
0.0
4d1oB-1l5jA:
0.0		 4d1oA-1l5jA:
20.71
4d1oB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4d1oA-1l5jA:
0.0
4d1oB-1l5jA:
0.0		 4d1oA-1l5jA:
20.71
4d1oB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4d1pA-1l5jA:
0.0
4d1pB-1l5jA:
0.0		 4d1pA-1l5jA:
20.71
4d1pB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4d1pA-1l5jA:
0.0
4d1pB-1l5jA:
0.0		 4d1pA-1l5jA:
20.71
4d1pB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4d2yA-1l5jA:
0.0
4d2yB-1l5jA:
0.0		 4d2yA-1l5jA:
19.28
4d2yB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4d2yA-1l5jA:
0.0
4d2yB-1l5jA:
0.0		 4d2yA-1l5jA:
19.28
4d2yB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4d30A-1l5jA:
0.0
4d30B-1l5jA:
0.0		 4d30A-1l5jA:
19.28
4d30B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4d30A-1l5jA:
0.0
4d30B-1l5jA:
0.0		 4d30A-1l5jA:
19.28
4d30B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4d31A-1l5jA:
0.0
4d31B-1l5jA:
0.0		 4d31A-1l5jA:
19.28
4d31B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4d31A-1l5jA:
0.0
4d31B-1l5jA:
0.0		 4d31A-1l5jA:
19.28
4d31B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 4d32A-1l5jA:
0.0
4d32B-1l5jA:
0.0		 4d32A-1l5jA:
19.28
4d32B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 4d33A-1l5jA:
0.0
4d33B-1l5jA:
0.0		 4d33A-1l5jA:
20.21
4d33B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4d33A-1l5jA:
0.0
4d33B-1l5jA:
0.0		 4d33A-1l5jA:
20.21
4d33B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 4d34A-1l5jA:
0.0
4d34B-1l5jA:
0.0		 4d34A-1l5jA:
20.21
4d34B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4d34A-1l5jA:
0.0
4d34B-1l5jA:
0.0		 4d34A-1l5jA:
20.21
4d34B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4d35A-1l5jA:
0.0
4d35B-1l5jA:
0.0		 4d35A-1l5jA:
20.21
4d35B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4d36A-1l5jA:
0.0
4d36B-1l5jA:
0.0		 4d36A-1l5jA:
20.21
4d36B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4d36A-1l5jA:
0.0
4d36B-1l5jA:
0.0		 4d36A-1l5jA:
20.21
4d36B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4d37A-1l5jA:
0.0
4d37B-1l5jA:
0.0		 4d37A-1l5jA:
20.21
4d37B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4d37A-1l5jA:
0.0
4d37B-1l5jA:
0.0		 4d37A-1l5jA:
20.21
4d37B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4d38A-1l5jA:
0.0
4d38B-1l5jA:
0.0		 4d38A-1l5jA:
20.21
4d38B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4d38A-1l5jA:
0.0
4d38B-1l5jA:
0.0		 4d38A-1l5jA:
20.21
4d38B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4d39A-1l5jA:
0.0
4d39B-1l5jA:
0.0		 4d39A-1l5jA:
20.21
4d39B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4d39A-1l5jA:
0.0
4d39B-1l5jA:
0.0		 4d39A-1l5jA:
20.21
4d39B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 4d3aA-1l5jA:
0.0
4d3aB-1l5jA:
0.0		 4d3aA-1l5jA:
20.21
4d3aB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4d3aA-1l5jA:
0.0
4d3aB-1l5jA:
0.0		 4d3aA-1l5jA:
20.21
4d3aB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4d3bA-1l5jA:
0.0
4d3bB-1l5jA:
0.0		 4d3bA-1l5jA:
19.28
4d3bB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4d3bA-1l5jA:
0.0
4d3bB-1l5jA:
0.0		 4d3bA-1l5jA:
19.28
4d3bB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.80A 4d7bA-1l5jA:
undetectable		 4d7bA-1l5jA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4d7oA-1l5jA:
0.0
4d7oB-1l5jA:
0.0		 4d7oA-1l5jA:
19.28
4d7oB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4d7oA-1l5jA:
0.0
4d7oB-1l5jA:
0.0		 4d7oA-1l5jA:
19.28
4d7oB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 PHE A 433
ALA A 519
LEU A 425
THR A 421
 None
 0.99A 4dtzA-1l5jA:
0.0		 4dtzA-1l5jA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 PHE A 433
ALA A 519
LEU A 425
THR A 421
 None
 0.96A 4dtzB-1l5jA:
undetectable		 4dtzB-1l5jA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 ARG A 422
THR A 456
GLN A 440
THR A 459
 None
 1.31A 4eahA-1l5jA:
3.3
4eahE-1l5jA:
3.3
4eahG-1l5jA:
0.0		 4eahA-1l5jA:
19.88
4eahE-1l5jA:
19.88
4eahG-1l5jA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4euxA-1l5jA:
0.0
4euxB-1l5jA:
0.0		 4euxA-1l5jA:
19.28
4euxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.39A 4euxA-1l5jA:
0.0
4euxB-1l5jA:
0.0		 4euxA-1l5jA:
19.28
4euxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ALA A 726
ASP A 725
VAL A 833
THR A 828
 None
 0.99A 4eyrA-1l5jA:
undetectable		 4eyrA-1l5jA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 ILE A 114
LEU A  81
LEU A 102
GLY A  91
ALA A  69
 None
 1.22A 4fogD-1l5jA:
0.0		 4fogD-1l5jA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4fvwA-1l5jA:
0.0
4fvwB-1l5jA:
0.0		 4fvwA-1l5jA:
19.28
4fvwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4fvwA-1l5jA:
0.0
4fvwB-1l5jA:
0.0		 4fvwA-1l5jA:
19.28
4fvwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4fvxA-1l5jA:
0.0
4fvxB-1l5jA:
0.0		 4fvxA-1l5jA:
19.28
4fvxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4fvxA-1l5jA:
0.0
4fvxB-1l5jA:
0.0		 4fvxA-1l5jA:
19.28
4fvxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4fvyA-1l5jA:
0.0
4fvyB-1l5jA:
0.0		 4fvyA-1l5jA:
19.28
4fvyB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 4fvyA-1l5jA:
0.0
4fvyB-1l5jA:
0.0		 4fvyA-1l5jA:
19.28
4fvyB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4fvzA-1l5jA:
0.0
4fvzB-1l5jA:
0.0		 4fvzA-1l5jA:
19.28
4fvzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4fvzA-1l5jA:
0.0
4fvzB-1l5jA:
0.0		 4fvzA-1l5jA:
19.28
4fvzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4fw0A-1l5jA:
0.0
4fw0B-1l5jA:
0.0		 4fw0A-1l5jA:
19.28
4fw0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4fw0A-1l5jA:
0.0
4fw0B-1l5jA:
0.0		 4fw0A-1l5jA:
19.28
4fw0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4gqeA-1l5jA:
0.0
4gqeB-1l5jA:
0.0		 4gqeA-1l5jA:
19.28
4gqeB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4gqeA-1l5jA:
0.0
4gqeB-1l5jA:
0.0		 4gqeA-1l5jA:
19.28
4gqeB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 LEU A 488
TRP A 651
ILE A 617
ASN A 845
 None
 1.41A 4i00A-1l5jA:
undetectable		 4i00A-1l5jA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 LEU A 488
TRP A 651
ILE A 617
ASN A 847
 None
 1.33A 4i00A-1l5jA:
undetectable		 4i00A-1l5jA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.91A 4i89A-1l5jA:
undetectable		 4i89A-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.86A 4ikiB-1l5jA:
undetectable		 4ikiB-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.87A 4ikjA-1l5jA:
undetectable
4ikjB-1l5jA:
undetectable		 4ikjA-1l5jA:
8.33
4ikjB-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.84A 4ikjA-1l5jA:
undetectable
4ikjB-1l5jA:
undetectable		 4ikjA-1l5jA:
8.33
4ikjB-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.84A 4ikkA-1l5jA:
undetectable
4ikkB-1l5jA:
undetectable		 4ikkA-1l5jA:
8.33
4ikkB-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.84A 4ikkA-1l5jA:
undetectable
4ikkB-1l5jA:
undetectable		 4ikkA-1l5jA:
8.33
4ikkB-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4imtA-1l5jA:
0.0
4imtB-1l5jA:
0.0		 4imtA-1l5jA:
19.28
4imtB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4imwA-1l5jA:
0.0
4imwB-1l5jA:
0.0		 4imwA-1l5jA:
19.28
4imwB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 4imxA-1l5jA:
0.0
4imxB-1l5jA:
0.0		 4imxA-1l5jA:
20.35
4imxB-1l5jA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4imxA-1l5jA:
0.0
4imxB-1l5jA:
0.0		 4imxA-1l5jA:
20.35
4imxB-1l5jA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 SER A 599
LEU A 579
CYH A 607
ALA A 592
GLY A 583
 None
 1.30A 4j7xB-1l5jA:
undetectable		 4j7xB-1l5jA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 4jsfA-1l5jA:
0.0
4jsfB-1l5jA:
0.0		 4jsfA-1l5jA:
19.28
4jsfB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4jsfA-1l5jA:
0.0
4jsfB-1l5jA:
0.0		 4jsfA-1l5jA:
19.28
4jsfB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4jsgA-1l5jA:
0.0
4jsgB-1l5jA:
0.0		 4jsgA-1l5jA:
19.28
4jsgB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4jsgA-1l5jA:
0.0
4jsgB-1l5jA:
0.0		 4jsgA-1l5jA:
19.28
4jsgB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.28A 4jsiA-1l5jA:
0.0
4jsiB-1l5jA:
0.0		 4jsiA-1l5jA:
19.28
4jsiB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4jsiA-1l5jA:
0.0
4jsiB-1l5jA:
0.0		 4jsiA-1l5jA:
19.28
4jsiB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4jsjA-1l5jA:
0.0
4jsjB-1l5jA:
0.0		 4jsjA-1l5jA:
19.28
4jsjB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4jsjA-1l5jA:
0.0
4jsjB-1l5jA:
0.0		 4jsjA-1l5jA:
19.28
4jsjB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4jskA-1l5jA:
0.0
4jskB-1l5jA:
0.0		 4jskA-1l5jA:
20.21
4jskB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4jskA-1l5jA:
0.0
4jskB-1l5jA:
0.0		 4jskA-1l5jA:
20.21
4jskB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4jslA-1l5jA:
0.0
4jslB-1l5jA:
0.0		 4jslA-1l5jA:
20.21
4jslB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4jslA-1l5jA:
0.0
4jslB-1l5jA:
0.0		 4jslA-1l5jA:
20.21
4jslB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4jsmA-1l5jA:
0.0
4jsmB-1l5jA:
0.0		 4jsmA-1l5jA:
20.21
4jsmB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 4jsmA-1l5jA:
0.0
4jsmB-1l5jA:
0.0		 4jsmA-1l5jA:
20.21
4jsmB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4k5dA-1l5jA:
0.0
4k5dB-1l5jA:
0.0		 4k5dA-1l5jA:
19.28
4k5dB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.38A 4k5dA-1l5jA:
0.0
4k5dB-1l5jA:
0.0		 4k5dA-1l5jA:
19.28
4k5dB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4k5eA-1l5jA:
0.0
4k5eB-1l5jA:
0.0		 4k5eA-1l5jA:
19.28
4k5eB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4k5eA-1l5jA:
0.0
4k5eB-1l5jA:
0.0		 4k5eA-1l5jA:
19.28
4k5eB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4k5gA-1l5jA:
0.0
4k5gB-1l5jA:
0.0		 4k5gA-1l5jA:
19.28
4k5gB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4k5gA-1l5jA:
0.0
4k5gB-1l5jA:
0.0		 4k5gA-1l5jA:
19.28
4k5gB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4k5hA-1l5jA:
0.0
4k5hB-1l5jA:
0.0		 4k5hA-1l5jA:
20.21
4k5hB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4k5hA-1l5jA:
0.0
4k5hB-1l5jA:
0.0		 4k5hA-1l5jA:
20.21
4k5hB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 4k5iA-1l5jA:
0.0
4k5iB-1l5jA:
0.0		 4k5iA-1l5jA:
20.21
4k5iB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4k5iA-1l5jA:
0.0
4k5iB-1l5jA:
0.0		 4k5iA-1l5jA:
20.21
4k5iB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 4k5jA-1l5jA:
0.0
4k5jB-1l5jA:
0.0		 4k5jA-1l5jA:
20.21
4k5jB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4k5jA-1l5jA:
undetectable
4k5jB-1l5jA:
undetectable		 4k5jA-1l5jA:
20.21
4k5jB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4k5kA-1l5jA:
0.0
4k5kB-1l5jA:
0.0		 4k5kA-1l5jA:
20.21
4k5kB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 4k5kA-1l5jA:
0.0
4k5kB-1l5jA:
0.0		 4k5kA-1l5jA:
20.21
4k5kB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4kcjA-1l5jA:
0.0
4kcjB-1l5jA:
0.0		 4kcjA-1l5jA:
19.28
4kcjB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4kcjA-1l5jA:
0.0
4kcjB-1l5jA:
0.0		 4kcjA-1l5jA:
19.28
4kcjB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4kcmA-1l5jA:
0.0
4kcmB-1l5jA:
0.0		 4kcmA-1l5jA:
19.28
4kcmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4kcnA-1l5jA:
0.0
4kcnB-1l5jA:
0.0		 4kcnA-1l5jA:
19.28
4kcnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4kcnA-1l5jA:
0.0
4kcnB-1l5jA:
0.0		 4kcnA-1l5jA:
19.28
4kcnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4kcoA-1l5jA:
0.0
4kcoB-1l5jA:
0.0		 4kcoA-1l5jA:
19.28
4kcoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4kcoA-1l5jA:
0.0
4kcoB-1l5jA:
0.0		 4kcoA-1l5jA:
19.28
4kcoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4kcpA-1l5jA:
0.0
4kcpB-1l5jA:
0.0		 4kcpA-1l5jA:
20.21
4kcpB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4kcpA-1l5jA:
0.0
4kcpB-1l5jA:
0.0		 4kcpA-1l5jA:
20.21
4kcpB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4kcqA-1l5jA:
0.0
4kcqB-1l5jA:
0.0		 4kcqA-1l5jA:
20.21
4kcqB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4kcqA-1l5jA:
0.0
4kcqB-1l5jA:
0.0		 4kcqA-1l5jA:
20.21
4kcqB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4kcrA-1l5jA:
0.0
4kcrB-1l5jA:
0.0		 4kcrA-1l5jA:
20.21
4kcrB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4kcrA-1l5jA:
0.0
4kcrB-1l5jA:
0.0		 4kcrA-1l5jA:
20.21
4kcrB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4kcsA-1l5jA:
0.0
4kcsB-1l5jA:
0.0		 4kcsA-1l5jA:
20.21
4kcsB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4kcsA-1l5jA:
0.0
4kcsB-1l5jA:
0.0		 4kcsA-1l5jA:
20.21
4kcsB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ILE A 223
PHE A 256
ILE A  17
LEU A 199
ILE A 220
 None
 1.04A 4kjkA-1l5jA:
undetectable		 4kjkA-1l5jA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 THR A 500
SER A 248
HIS A 444
GLY A 774
SER A 441
 None
None
F3S  A 868 (-4.2A)
None
None
 1.46A 4kn2A-1l5jA:
0.0		 4kn2A-1l5jA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 4luwA-1l5jA:
0.0
4luwB-1l5jA:
0.0		 4luwA-1l5jA:
20.19
4luwB-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4luwA-1l5jA:
0.0
4luwB-1l5jA:
0.0		 4luwA-1l5jA:
20.19
4luwB-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4luxA-1l5jA:
0.0
4luxB-1l5jA:
0.0		 4luxA-1l5jA:
19.28
4luxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4luxA-1l5jA:
0.0
4luxB-1l5jA:
0.0		 4luxA-1l5jA:
19.28
4luxB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 ARG A 467
PRO A  55
VAL A 264
VAL A  57
 None
 0.88A 4mk4A-1l5jA:
2.5		 4mk4A-1l5jA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.37A 4nosC-1l5jA:
0.0
4nosD-1l5jA:
0.0		 4nosC-1l5jA:
19.37
4nosD-1l5jA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4nosC-1l5jA:
0.0
4nosD-1l5jA:
0.0		 4nosC-1l5jA:
19.37
4nosD-1l5jA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ILE A 479
ILE A 616
LEU A 611
GLY A 505
SER A 507
 None
 0.90A 4o1eB-1l5jA:
undetectable		 4o1eB-1l5jA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 4 ALA A 808
ALA A 811
ALA A 812
ALA A 815
 None
 0.11A 4oaeA-1l5jA:
0.0		 4oaeA-1l5jA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ILE A 223
PHE A 256
ILE A  17
LEU A 199
ILE A 220
 None
 1.03A 4p3qA-1l5jA:
undetectable		 4p3qA-1l5jA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 THR A 177
GLY A 275
TYR A 235
GLY A 237
 None
 0.90A 4rdxA-1l5jA:
undetectable		 4rdxA-1l5jA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 4rvjB-1l5jA:
undetectable		 4rvjB-1l5jA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.78A 4rvjD-1l5jA:
undetectable		 4rvjD-1l5jA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4uchA-1l5jA:
0.0
4uchB-1l5jA:
0.0		 4uchA-1l5jA:
19.98
4uchB-1l5jA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4uchA-1l5jA:
0.0
4uchB-1l5jA:
0.0		 4uchA-1l5jA:
19.98
4uchB-1l5jA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4ugzA-1l5jA:
0.0
4ugzB-1l5jA:
0.0		 4ugzA-1l5jA:
19.28
4ugzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4ugzA-1l5jA:
0.0
4ugzB-1l5jA:
0.0		 4ugzA-1l5jA:
19.28
4ugzB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uh0A-1l5jA:
0.0
4uh0B-1l5jA:
0.0		 4uh0A-1l5jA:
19.28
4uh0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4uh1A-1l5jA:
0.0
4uh1B-1l5jA:
0.0		 4uh1A-1l5jA:
19.28
4uh1B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4uh2A-1l5jA:
0.0
4uh2B-1l5jA:
0.0		 4uh2A-1l5jA:
19.28
4uh2B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4uh2A-1l5jA:
0.0
4uh2B-1l5jA:
0.0		 4uh2A-1l5jA:
19.28
4uh2B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uh3A-1l5jA:
0.0
4uh3B-1l5jA:
0.0		 4uh3A-1l5jA:
19.28
4uh3B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 4uh3A-1l5jA:
0.0
4uh3B-1l5jA:
0.0		 4uh3A-1l5jA:
19.28
4uh3B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4uh4A-1l5jA:
0.0
4uh4B-1l5jA:
0.0		 4uh4A-1l5jA:
19.28
4uh4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4uh4A-1l5jA:
0.0
4uh4B-1l5jA:
0.0		 4uh4A-1l5jA:
19.28
4uh4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4uh5A-1l5jA:
0.0
4uh5B-1l5jA:
0.0		 4uh5A-1l5jA:
19.93
4uh5B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4uh5A-1l5jA:
0.0
4uh5B-1l5jA:
0.0		 4uh5A-1l5jA:
19.93
4uh5B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4uh6A-1l5jA:
0.0
4uh6B-1l5jA:
0.0		 4uh6A-1l5jA:
19.93
4uh6B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4uh6A-1l5jA:
0.0
4uh6B-1l5jA:
0.0		 4uh6A-1l5jA:
19.93
4uh6B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uh7A-1l5jA:
0.0
4uh7B-1l5jA:
0.0		 4uh7A-1l5jA:
20.21
4uh7B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4uh7A-1l5jA:
0.0
4uh7B-1l5jA:
0.0		 4uh7A-1l5jA:
20.21
4uh7B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 4uh8A-1l5jA:
0.0
4uh8B-1l5jA:
0.0		 4uh8A-1l5jA:
20.21
4uh8B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uh9A-1l5jA:
0.0
4uh9B-1l5jA:
0.0		 4uh9A-1l5jA:
20.21
4uh9B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4uh9A-1l5jA:
0.0
4uh9B-1l5jA:
0.0		 4uh9A-1l5jA:
20.21
4uh9B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uhaA-1l5jA:
0.0
4uhaB-1l5jA:
0.0		 4uhaA-1l5jA:
20.21
4uhaB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4uhaA-1l5jA:
0.0
4uhaB-1l5jA:
0.0		 4uhaA-1l5jA:
20.21
4uhaB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4upmA-1l5jA:
0.0
4upmB-1l5jA:
0.0		 4upmA-1l5jA:
19.28
4upmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4upmA-1l5jA:
0.0
4upmB-1l5jA:
0.0		 4upmA-1l5jA:
19.28
4upmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4upoA-1l5jA:
0.0
4upoB-1l5jA:
0.0		 4upoA-1l5jA:
19.28
4upoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 4upoA-1l5jA:
0.0
4upoB-1l5jA:
0.0		 4upoA-1l5jA:
19.28
4upoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uppA-1l5jA:
0.0
4uppB-1l5jA:
0.0		 4uppA-1l5jA:
19.28
4uppB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 4uppA-1l5jA:
0.0
4uppB-1l5jA:
0.0		 4uppA-1l5jA:
19.28
4uppB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4upqA-1l5jA:
0.0
4upqB-1l5jA:
0.0		 4upqA-1l5jA:
20.21
4upqB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4upqA-1l5jA:
0.0
4upqB-1l5jA:
0.0		 4upqA-1l5jA:
20.21
4upqB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4uprA-1l5jA:
0.0
4uprB-1l5jA:
0.0		 4uprA-1l5jA:
20.21
4uprB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4uprA-1l5jA:
0.0
4uprB-1l5jA:
0.0		 4uprA-1l5jA:
20.21
4uprB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 4upsA-1l5jA:
0.0
4upsB-1l5jA:
0.0		 4upsA-1l5jA:
20.21
4upsB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 4upsA-1l5jA:
0.0
4upsB-1l5jA:
0.0		 4upsA-1l5jA:
20.21
4upsB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4uptA-1l5jA:
0.0
4uptB-1l5jA:
0.0		 4uptA-1l5jA:
20.21
4uptB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 4uptA-1l5jA:
0.0
4uptB-1l5jA:
0.0		 4uptA-1l5jA:
20.21
4uptB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 4v3uA-1l5jA:
0.0
4v3uB-1l5jA:
0.0		 4v3uA-1l5jA:
20.19
4v3uB-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 4v3uC-1l5jA:
0.0
4v3uD-1l5jA:
0.0		 4v3uC-1l5jA:
20.19
4v3uD-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4v3uC-1l5jA:
0.0
4v3uD-1l5jA:
0.0		 4v3uC-1l5jA:
20.19
4v3uD-1l5jA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 4v3vA-1l5jA:
0.0
4v3vB-1l5jA:
0.0		 4v3vA-1l5jA:
19.28
4v3vB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4v3wA-1l5jA:
0.0
4v3wB-1l5jA:
undetectable		 4v3wA-1l5jA:
19.28
4v3wB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 4v3yA-1l5jA:
0.0
4v3yB-1l5jA:
0.0		 4v3yA-1l5jA:
19.28
4v3yB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 4v3yA-1l5jA:
undetectable
4v3yB-1l5jA:
0.0		 4v3yA-1l5jA:
19.28
4v3yB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 4v3zA-1l5jA:
0.0
4v3zB-1l5jA:
0.0		 4v3zA-1l5jA:
19.28
4v3zB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 LEU A 123
GLY A 290
PRO A 293
LEU A 335
LEU A 347
 None
 1.27A 4x61A-1l5jA:
2.4		 4x61A-1l5jA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 4 ARG A 535
GLY A 583
GLU A 582
 None
 0.66A 4z2dB-1l5jA:
0.2
4z2dC-1l5jA:
undetectable		 4z2dB-1l5jA:
21.80
4z2dC-1l5jA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_F_FOLF201_0
(FOLATE ECF
TRANSPORTER)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 SER A 413
MET A 773
ALA A 188
THR A 456
ARG A 422
 None
TRA  A 866 (-4.1A)
None
None
None
 1.33A 4z7fF-1l5jA:
0.0		 4z7fF-1l5jA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.26A 5ad4A-1l5jA:
0.0
5ad4B-1l5jA:
0.0		 5ad4A-1l5jA:
19.28
5ad4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5ad4A-1l5jA:
0.0
5ad4B-1l5jA:
0.0		 5ad4A-1l5jA:
19.28
5ad4B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5ad5A-1l5jA:
0.0
5ad5B-1l5jA:
0.0		 5ad5A-1l5jA:
19.28
5ad5B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5adaA-1l5jA:
0.0
5adaB-1l5jA:
0.0		 5adaA-1l5jA:
19.28
5adaB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5adcA-1l5jA:
0.0
5adcB-1l5jA:
0.0		 5adcA-1l5jA:
19.28
5adcB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5adcA-1l5jA:
0.0
5adcB-1l5jA:
0.0		 5adcA-1l5jA:
19.28
5adcB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 5adfA-1l5jA:
0.0
5adfB-1l5jA:
0.0		 5adfA-1l5jA:
19.93
5adfB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 5adgA-1l5jA:
0.0
5adgB-1l5jA:
0.0		 5adgA-1l5jA:
19.93
5adgB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5adgA-1l5jA:
0.0
5adgB-1l5jA:
0.0		 5adgA-1l5jA:
19.93
5adgB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 5adjA-1l5jA:
0.0
5adjB-1l5jA:
0.0		 5adjA-1l5jA:
20.21
5adjB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5adjA-1l5jA:
0.0
5adjB-1l5jA:
0.0		 5adjA-1l5jA:
20.21
5adjB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5adkA-1l5jA:
0.0
5adkB-1l5jA:
0.0		 5adkA-1l5jA:
20.21
5adkB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5adkA-1l5jA:
0.0
5adkB-1l5jA:
0.0		 5adkA-1l5jA:
20.21
5adkB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5adlA-1l5jA:
undetectable
5adlB-1l5jA:
3.4		 5adlA-1l5jA:
20.21
5adlB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5admA-1l5jA:
0.0
5admB-1l5jA:
0.0		 5admA-1l5jA:
20.21
5admB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5admA-1l5jA:
0.0
5admB-1l5jA:
0.0		 5admA-1l5jA:
20.21
5admB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5adnA-1l5jA:
0.0
5adnB-1l5jA:
0.0		 5adnA-1l5jA:
20.21
5adnB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 5adnA-1l5jA:
0.0
5adnB-1l5jA:
0.0		 5adnA-1l5jA:
20.21
5adnB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5agkA-1l5jA:
0.0
5agkB-1l5jA:
0.0		 5agkA-1l5jA:
19.28
5agkB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5agkA-1l5jA:
0.0
5agkB-1l5jA:
0.0		 5agkA-1l5jA:
19.28
5agkB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5aglA-1l5jA:
0.0
5aglB-1l5jA:
0.0		 5aglA-1l5jA:
19.28
5aglB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5aglA-1l5jA:
0.0
5aglB-1l5jA:
0.0		 5aglA-1l5jA:
19.28
5aglB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5agmA-1l5jA:
0.0
5agmB-1l5jA:
0.0		 5agmA-1l5jA:
19.28
5agmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5agmA-1l5jA:
0.0
5agmB-1l5jA:
0.0		 5agmA-1l5jA:
19.28
5agmB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5agnA-1l5jA:
0.0
5agnB-1l5jA:
0.0		 5agnA-1l5jA:
19.28
5agnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 5agnA-1l5jA:
0.0
5agnB-1l5jA:
0.0		 5agnA-1l5jA:
19.28
5agnB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5agoA-1l5jA:
0.0
5agoB-1l5jA:
0.0		 5agoA-1l5jA:
19.28
5agoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5agoA-1l5jA:
0.0
5agoB-1l5jA:
0.0		 5agoA-1l5jA:
19.28
5agoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 5agpA-1l5jA:
0.0
5agpB-1l5jA:
0.0		 5agpA-1l5jA:
19.28
5agpB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 5agpA-1l5jA:
0.0
5agpB-1l5jA:
0.0		 5agpA-1l5jA:
19.28
5agpB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 SER A 512
GLY A 243
THR A 790
GLU A 601
 None
None
F3S  A 868 (-3.4A)
None
 1.20A 5btiA-1l5jA:
0.0
5btiB-1l5jA:
0.8		 5btiA-1l5jA:
21.53
5btiB-1l5jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 SER A 512
GLY A 243
THR A 790
GLU A 601
 None
None
F3S  A 868 (-3.4A)
None
 1.21A 5btiC-1l5jA:
undetectable
5btiD-1l5jA:
undetectable		 5btiC-1l5jA:
21.53
5btiD-1l5jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 SER A 248
ALA A 249
HIS A 197
PRO A 184
 None
 1.18A 5dzkd-1l5jA:
undetectable
5dzkr-1l5jA:
undetectable		 5dzkd-1l5jA:
13.89
5dzkr-1l5jA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 SER A 248
ALA A 249
HIS A 197
PRO A 184
 None
 1.18A 5dzkF-1l5jA:
0.6
5dzkT-1l5jA:
undetectable		 5dzkF-1l5jA:
13.89
5dzkT-1l5jA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.87A 5e5jB-1l5jA:
undetectable		 5e5jB-1l5jA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.19A 5eeuA-1l5jA:
0.0
5eeuB-1l5jA:
0.0		 5eeuA-1l5jA:
7.07
5eeuB-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeuB-1l5jA:
0.0
5eeuC-1l5jA:
undetectable		 5eeuB-1l5jA:
7.07
5eeuC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeuC-1l5jA:
0.0
5eeuD-1l5jA:
0.0		 5eeuC-1l5jA:
7.07
5eeuD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5eeuD-1l5jA:
0.0
5eeuE-1l5jA:
0.0		 5eeuD-1l5jA:
7.07
5eeuE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 5eeuE-1l5jA:
0.0
5eeuF-1l5jA:
0.0		 5eeuE-1l5jA:
7.07
5eeuF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eeuF-1l5jA:
0.0
5eeuG-1l5jA:
0.0		 5eeuF-1l5jA:
7.07
5eeuG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eeuG-1l5jA:
undetectable
5eeuH-1l5jA:
undetectable		 5eeuG-1l5jA:
7.07
5eeuH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 5eeuH-1l5jA:
0.0
5eeuI-1l5jA:
0.0		 5eeuH-1l5jA:
7.07
5eeuI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eeuI-1l5jA:
undetectable
5eeuJ-1l5jA:
0.0		 5eeuI-1l5jA:
7.07
5eeuJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeuJ-1l5jA:
0.0
5eeuK-1l5jA:
0.0		 5eeuJ-1l5jA:
7.07
5eeuK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5eeuA-1l5jA:
0.0
5eeuK-1l5jA:
0.0		 5eeuA-1l5jA:
7.07
5eeuK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.11A 5eeuL-1l5jA:
undetectable
5eeuV-1l5jA:
undetectable		 5eeuL-1l5jA:
7.07
5eeuV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eeuL-1l5jA:
undetectable
5eeuM-1l5jA:
undetectable		 5eeuL-1l5jA:
7.07
5eeuM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eeuM-1l5jA:
undetectable
5eeuN-1l5jA:
undetectable		 5eeuM-1l5jA:
7.07
5eeuN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eeuN-1l5jA:
undetectable
5eeuO-1l5jA:
undetectable		 5eeuN-1l5jA:
7.07
5eeuO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eeuO-1l5jA:
undetectable
5eeuP-1l5jA:
0.0		 5eeuO-1l5jA:
7.07
5eeuP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eeuP-1l5jA:
undetectable
5eeuQ-1l5jA:
undetectable		 5eeuP-1l5jA:
7.07
5eeuQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 5eeuQ-1l5jA:
0.0
5eeuR-1l5jA:
undetectable		 5eeuQ-1l5jA:
7.07
5eeuR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eeuR-1l5jA:
undetectable
5eeuS-1l5jA:
undetectable		 5eeuR-1l5jA:
7.07
5eeuS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eeuS-1l5jA:
undetectable
5eeuT-1l5jA:
undetectable		 5eeuS-1l5jA:
7.07
5eeuT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eeuT-1l5jA:
undetectable
5eeuU-1l5jA:
undetectable		 5eeuT-1l5jA:
7.07
5eeuU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eeuU-1l5jA:
undetectable
5eeuV-1l5jA:
undetectable		 5eeuU-1l5jA:
7.07
5eeuV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eevB-1l5jA:
0.0
5eevC-1l5jA:
undetectable		 5eevB-1l5jA:
7.07
5eevC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eevC-1l5jA:
undetectable
5eevD-1l5jA:
undetectable		 5eevC-1l5jA:
7.07
5eevD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5eevD-1l5jA:
0.0
5eevE-1l5jA:
0.0		 5eevD-1l5jA:
7.07
5eevE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eevE-1l5jA:
undetectable
5eevF-1l5jA:
0.0		 5eevE-1l5jA:
7.07
5eevF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eevF-1l5jA:
undetectable
5eevG-1l5jA:
0.0		 5eevF-1l5jA:
7.07
5eevG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eevG-1l5jA:
undetectable
5eevH-1l5jA:
0.0		 5eevG-1l5jA:
7.07
5eevH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 5eevH-1l5jA:
0.0
5eevI-1l5jA:
0.0		 5eevH-1l5jA:
7.07
5eevI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5eevI-1l5jA:
undetectable
5eevJ-1l5jA:
undetectable		 5eevI-1l5jA:
7.07
5eevJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eevJ-1l5jA:
0.0
5eevK-1l5jA:
0.0		 5eevJ-1l5jA:
7.07
5eevK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5eevA-1l5jA:
0.0
5eevK-1l5jA:
undetectable		 5eevA-1l5jA:
7.07
5eevK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eevL-1l5jA:
undetectable
5eevM-1l5jA:
undetectable		 5eevL-1l5jA:
7.07
5eevM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eevM-1l5jA:
undetectable
5eevN-1l5jA:
undetectable		 5eevM-1l5jA:
7.07
5eevN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eevN-1l5jA:
undetectable
5eevO-1l5jA:
undetectable		 5eevN-1l5jA:
7.07
5eevO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eevO-1l5jA:
undetectable
5eevP-1l5jA:
undetectable		 5eevO-1l5jA:
7.07
5eevP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eevP-1l5jA:
undetectable
5eevQ-1l5jA:
undetectable		 5eevP-1l5jA:
7.07
5eevQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 5eevQ-1l5jA:
0.0
5eevR-1l5jA:
undetectable		 5eevQ-1l5jA:
7.07
5eevR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eevR-1l5jA:
undetectable
5eevS-1l5jA:
undetectable		 5eevR-1l5jA:
7.07
5eevS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eevS-1l5jA:
undetectable
5eevT-1l5jA:
undetectable		 5eevS-1l5jA:
7.07
5eevT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eevT-1l5jA:
undetectable
5eevU-1l5jA:
undetectable		 5eevT-1l5jA:
7.07
5eevU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5eevU-1l5jA:
undetectable
5eevV-1l5jA:
undetectable		 5eevU-1l5jA:
7.07
5eevV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eewB-1l5jA:
0.0
5eewC-1l5jA:
undetectable		 5eewB-1l5jA:
7.07
5eewC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eewC-1l5jA:
0.0
5eewD-1l5jA:
0.0		 5eewC-1l5jA:
7.07
5eewD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5eewD-1l5jA:
0.0
5eewE-1l5jA:
0.0		 5eewD-1l5jA:
7.07
5eewE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eewE-1l5jA:
0.0
5eewF-1l5jA:
0.0		 5eewE-1l5jA:
7.07
5eewF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eewF-1l5jA:
undetectable
5eewG-1l5jA:
0.0		 5eewF-1l5jA:
7.07
5eewG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eewG-1l5jA:
0.0
5eewH-1l5jA:
0.0		 5eewG-1l5jA:
7.07
5eewH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.16A 5eewH-1l5jA:
0.0
5eewI-1l5jA:
0.0		 5eewH-1l5jA:
7.07
5eewI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5eewI-1l5jA:
undetectable
5eewJ-1l5jA:
0.0		 5eewI-1l5jA:
7.07
5eewJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eewJ-1l5jA:
0.0
5eewK-1l5jA:
undetectable		 5eewJ-1l5jA:
7.07
5eewK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5eewA-1l5jA:
0.0
5eewK-1l5jA:
undetectable		 5eewA-1l5jA:
7.07
5eewK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eewL-1l5jA:
undetectable
5eewM-1l5jA:
undetectable		 5eewL-1l5jA:
7.07
5eewM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5eewM-1l5jA:
undetectable
5eewN-1l5jA:
undetectable		 5eewM-1l5jA:
7.07
5eewN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eewN-1l5jA:
undetectable
5eewO-1l5jA:
undetectable		 5eewN-1l5jA:
7.07
5eewO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eewO-1l5jA:
undetectable
5eewP-1l5jA:
undetectable		 5eewO-1l5jA:
7.07
5eewP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eewP-1l5jA:
undetectable
5eewQ-1l5jA:
undetectable		 5eewP-1l5jA:
7.07
5eewQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.09A 5eewQ-1l5jA:
undetectable
5eewR-1l5jA:
undetectable		 5eewQ-1l5jA:
7.07
5eewR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eewR-1l5jA:
undetectable
5eewS-1l5jA:
undetectable		 5eewR-1l5jA:
7.07
5eewS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eewS-1l5jA:
undetectable
5eewT-1l5jA:
undetectable		 5eewS-1l5jA:
7.07
5eewT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eewT-1l5jA:
undetectable
5eewU-1l5jA:
undetectable		 5eewT-1l5jA:
7.07
5eewU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5eewU-1l5jA:
undetectable
5eewV-1l5jA:
undetectable		 5eewU-1l5jA:
7.07
5eewV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eexB-1l5jA:
0.0
5eexC-1l5jA:
undetectable		 5eexB-1l5jA:
7.07
5eexC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eexC-1l5jA:
undetectable
5eexD-1l5jA:
0.0		 5eexC-1l5jA:
7.07
5eexD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5eexD-1l5jA:
0.0
5eexE-1l5jA:
0.0		 5eexD-1l5jA:
7.07
5eexE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eexE-1l5jA:
0.0
5eexF-1l5jA:
0.0		 5eexE-1l5jA:
7.07
5eexF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eexF-1l5jA:
undetectable
5eexG-1l5jA:
0.0		 5eexF-1l5jA:
7.07
5eexG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eexG-1l5jA:
0.0
5eexH-1l5jA:
0.0		 5eexG-1l5jA:
7.07
5eexH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eexH-1l5jA:
0.0
5eexI-1l5jA:
0.0		 5eexH-1l5jA:
7.07
5eexI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5eexI-1l5jA:
0.0
5eexJ-1l5jA:
0.0		 5eexI-1l5jA:
7.07
5eexJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eexJ-1l5jA:
0.0
5eexK-1l5jA:
0.0		 5eexJ-1l5jA:
7.07
5eexK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5eexA-1l5jA:
0.0
5eexK-1l5jA:
undetectable		 5eexA-1l5jA:
7.07
5eexK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 5eexL-1l5jA:
undetectable
5eexV-1l5jA:
undetectable		 5eexL-1l5jA:
7.07
5eexV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eexL-1l5jA:
undetectable
5eexM-1l5jA:
undetectable		 5eexL-1l5jA:
7.07
5eexM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eexM-1l5jA:
undetectable
5eexN-1l5jA:
undetectable		 5eexM-1l5jA:
7.07
5eexN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eexN-1l5jA:
undetectable
5eexO-1l5jA:
undetectable		 5eexN-1l5jA:
7.07
5eexO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eexO-1l5jA:
0.0
5eexP-1l5jA:
undetectable		 5eexO-1l5jA:
7.07
5eexP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eexP-1l5jA:
undetectable
5eexQ-1l5jA:
undetectable		 5eexP-1l5jA:
7.07
5eexQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eexQ-1l5jA:
undetectable
5eexR-1l5jA:
0.0		 5eexQ-1l5jA:
7.07
5eexR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eexR-1l5jA:
undetectable
5eexS-1l5jA:
undetectable		 5eexR-1l5jA:
7.07
5eexS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eexS-1l5jA:
undetectable
5eexT-1l5jA:
undetectable		 5eexS-1l5jA:
7.07
5eexT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eexT-1l5jA:
undetectable
5eexU-1l5jA:
undetectable		 5eexT-1l5jA:
7.07
5eexU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5eexU-1l5jA:
0.0
5eexV-1l5jA:
undetectable		 5eexU-1l5jA:
7.07
5eexV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeyB-1l5jA:
0.0
5eeyC-1l5jA:
undetectable		 5eeyB-1l5jA:
7.07
5eeyC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeyC-1l5jA:
0.0
5eeyD-1l5jA:
0.0		 5eeyC-1l5jA:
7.07
5eeyD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5eeyD-1l5jA:
0.0
5eeyE-1l5jA:
0.0		 5eeyD-1l5jA:
7.07
5eeyE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeyE-1l5jA:
undetectable
5eeyF-1l5jA:
undetectable		 5eeyE-1l5jA:
7.07
5eeyF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eeyF-1l5jA:
0.0
5eeyG-1l5jA:
0.0		 5eeyF-1l5jA:
7.07
5eeyG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eeyG-1l5jA:
0.0
5eeyH-1l5jA:
0.0		 5eeyG-1l5jA:
7.07
5eeyH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeyH-1l5jA:
0.0
5eeyI-1l5jA:
0.0		 5eeyH-1l5jA:
7.07
5eeyI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5eeyI-1l5jA:
0.0
5eeyJ-1l5jA:
undetectable		 5eeyI-1l5jA:
7.07
5eeyJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eeyJ-1l5jA:
0.0
5eeyK-1l5jA:
undetectable		 5eeyJ-1l5jA:
7.07
5eeyK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5eeyA-1l5jA:
0.0
5eeyK-1l5jA:
undetectable		 5eeyA-1l5jA:
7.07
5eeyK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 5eeyL-1l5jA:
undetectable
5eeyV-1l5jA:
undetectable		 5eeyL-1l5jA:
7.07
5eeyV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eeyL-1l5jA:
undetectable
5eeyM-1l5jA:
undetectable		 5eeyL-1l5jA:
7.07
5eeyM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5eeyM-1l5jA:
0.0
5eeyN-1l5jA:
0.0		 5eeyM-1l5jA:
7.07
5eeyN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eeyN-1l5jA:
undetectable
5eeyO-1l5jA:
undetectable		 5eeyN-1l5jA:
7.07
5eeyO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eeyO-1l5jA:
undetectable
5eeyP-1l5jA:
undetectable		 5eeyO-1l5jA:
7.07
5eeyP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eeyP-1l5jA:
undetectable
5eeyQ-1l5jA:
undetectable		 5eeyP-1l5jA:
7.07
5eeyQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eeyQ-1l5jA:
0.0
5eeyR-1l5jA:
0.0		 5eeyQ-1l5jA:
7.07
5eeyR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eeyR-1l5jA:
undetectable
5eeyS-1l5jA:
undetectable		 5eeyR-1l5jA:
7.07
5eeyS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eeyS-1l5jA:
undetectable
5eeyT-1l5jA:
undetectable		 5eeyS-1l5jA:
7.07
5eeyT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eeyT-1l5jA:
undetectable
5eeyU-1l5jA:
undetectable		 5eeyT-1l5jA:
7.07
5eeyU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 5eeyU-1l5jA:
0.0
5eeyV-1l5jA:
undetectable		 5eeyU-1l5jA:
7.07
5eeyV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eezB-1l5jA:
0.0
5eezC-1l5jA:
0.0		 5eezB-1l5jA:
7.07
5eezC-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eezC-1l5jA:
0.0
5eezD-1l5jA:
0.0		 5eezC-1l5jA:
7.07
5eezD-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5eezD-1l5jA:
0.0
5eezE-1l5jA:
0.0		 5eezD-1l5jA:
7.07
5eezE-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eezE-1l5jA:
0.0
5eezF-1l5jA:
0.0		 5eezE-1l5jA:
7.07
5eezF-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5eezF-1l5jA:
undetectable
5eezG-1l5jA:
0.0		 5eezF-1l5jA:
7.07
5eezG-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5eezG-1l5jA:
0.0
5eezH-1l5jA:
0.0		 5eezG-1l5jA:
7.07
5eezH-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eezH-1l5jA:
0.0
5eezI-1l5jA:
0.0		 5eezH-1l5jA:
7.07
5eezI-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5eezI-1l5jA:
0.0
5eezJ-1l5jA:
0.0		 5eezI-1l5jA:
7.07
5eezJ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5eezJ-1l5jA:
0.0
5eezK-1l5jA:
0.0		 5eezJ-1l5jA:
7.07
5eezK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5eezA-1l5jA:
0.0
5eezK-1l5jA:
0.0		 5eezA-1l5jA:
7.07
5eezK-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 5eezL-1l5jA:
undetectable
5eezV-1l5jA:
undetectable		 5eezL-1l5jA:
7.07
5eezV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5eezL-1l5jA:
0.0
5eezM-1l5jA:
0.0		 5eezL-1l5jA:
7.07
5eezM-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5eezM-1l5jA:
0.0
5eezN-1l5jA:
0.0		 5eezM-1l5jA:
7.07
5eezN-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eezN-1l5jA:
undetectable
5eezO-1l5jA:
undetectable		 5eezN-1l5jA:
7.07
5eezO-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eezO-1l5jA:
undetectable
5eezP-1l5jA:
undetectable		 5eezO-1l5jA:
7.07
5eezP-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eezP-1l5jA:
undetectable
5eezQ-1l5jA:
undetectable		 5eezP-1l5jA:
7.07
5eezQ-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5eezQ-1l5jA:
0.0
5eezR-1l5jA:
0.0		 5eezQ-1l5jA:
7.07
5eezR-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eezR-1l5jA:
undetectable
5eezS-1l5jA:
undetectable		 5eezR-1l5jA:
7.07
5eezS-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5eezS-1l5jA:
undetectable
5eezT-1l5jA:
undetectable		 5eezS-1l5jA:
7.07
5eezT-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.12A 5eezT-1l5jA:
undetectable
5eezU-1l5jA:
undetectable		 5eezT-1l5jA:
7.07
5eezU-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 5eezU-1l5jA:
undetectable
5eezV-1l5jA:
undetectable		 5eezU-1l5jA:
7.07
5eezV-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef0B-1l5jA:
0.0
5ef0C-1l5jA:
0.0		 5ef0B-1l5jA:
7.07
5ef0C-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef0C-1l5jA:
0.0
5ef0D-1l5jA:
0.0		 5ef0C-1l5jA:
7.07
5ef0D-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5ef0D-1l5jA:
0.0
5ef0E-1l5jA:
0.0		 5ef0D-1l5jA:
7.07
5ef0E-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef0E-1l5jA:
0.0
5ef0F-1l5jA:
0.0		 5ef0E-1l5jA:
7.07
5ef0F-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef0F-1l5jA:
0.0
5ef0G-1l5jA:
0.0		 5ef0F-1l5jA:
7.07
5ef0G-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef0G-1l5jA:
0.0
5ef0H-1l5jA:
0.0		 5ef0G-1l5jA:
7.07
5ef0H-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef0H-1l5jA:
0.0
5ef0I-1l5jA:
0.0		 5ef0H-1l5jA:
7.07
5ef0I-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef0I-1l5jA:
0.0
5ef0J-1l5jA:
0.0		 5ef0I-1l5jA:
7.07
5ef0J-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef0J-1l5jA:
0.0
5ef0K-1l5jA:
0.0		 5ef0J-1l5jA:
7.07
5ef0K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5ef0A-1l5jA:
undetectable
5ef0K-1l5jA:
undetectable		 5ef0A-1l5jA:
7.07
5ef0K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 5ef0L-1l5jA:
0.0
5ef0V-1l5jA:
0.0		 5ef0L-1l5jA:
7.07
5ef0V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef0L-1l5jA:
0.0
5ef0M-1l5jA:
0.0		 5ef0L-1l5jA:
7.07
5ef0M-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5ef0M-1l5jA:
0.0
5ef0N-1l5jA:
0.0		 5ef0M-1l5jA:
7.07
5ef0N-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef0N-1l5jA:
undetectable
5ef0O-1l5jA:
undetectable		 5ef0N-1l5jA:
7.07
5ef0O-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef0O-1l5jA:
undetectable
5ef0P-1l5jA:
0.0		 5ef0O-1l5jA:
7.07
5ef0P-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef0P-1l5jA:
undetectable
5ef0Q-1l5jA:
undetectable		 5ef0P-1l5jA:
7.07
5ef0Q-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef0Q-1l5jA:
0.0
5ef0R-1l5jA:
0.0		 5ef0Q-1l5jA:
7.07
5ef0R-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef0R-1l5jA:
undetectable
5ef0S-1l5jA:
undetectable		 5ef0R-1l5jA:
7.07
5ef0S-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef0S-1l5jA:
undetectable
5ef0T-1l5jA:
undetectable		 5ef0S-1l5jA:
7.07
5ef0T-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef0T-1l5jA:
undetectable
5ef0U-1l5jA:
undetectable		 5ef0T-1l5jA:
7.07
5ef0U-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 5ef0U-1l5jA:
0.0
5ef0V-1l5jA:
undetectable		 5ef0U-1l5jA:
7.07
5ef0V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef1B-1l5jA:
0.0
5ef1C-1l5jA:
0.0		 5ef1B-1l5jA:
7.07
5ef1C-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef1C-1l5jA:
0.0
5ef1D-1l5jA:
0.0		 5ef1C-1l5jA:
7.07
5ef1D-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5ef1D-1l5jA:
0.0
5ef1E-1l5jA:
0.0		 5ef1D-1l5jA:
7.07
5ef1E-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef1E-1l5jA:
0.0
5ef1F-1l5jA:
0.0		 5ef1E-1l5jA:
7.07
5ef1F-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef1F-1l5jA:
0.0
5ef1G-1l5jA:
0.0		 5ef1F-1l5jA:
7.07
5ef1G-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef1G-1l5jA:
0.0
5ef1H-1l5jA:
0.0		 5ef1G-1l5jA:
7.07
5ef1H-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef1H-1l5jA:
0.0
5ef1I-1l5jA:
0.0		 5ef1H-1l5jA:
7.07
5ef1I-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef1I-1l5jA:
0.0
5ef1J-1l5jA:
0.0		 5ef1I-1l5jA:
7.07
5ef1J-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef1J-1l5jA:
0.0
5ef1K-1l5jA:
0.0		 5ef1J-1l5jA:
7.07
5ef1K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5ef1A-1l5jA:
0.0
5ef1K-1l5jA:
0.0		 5ef1A-1l5jA:
7.07
5ef1K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 5ef1L-1l5jA:
undetectable
5ef1V-1l5jA:
undetectable		 5ef1L-1l5jA:
7.07
5ef1V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef1L-1l5jA:
0.0
5ef1M-1l5jA:
0.0		 5ef1L-1l5jA:
7.07
5ef1M-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5ef1M-1l5jA:
0.0
5ef1N-1l5jA:
0.0		 5ef1M-1l5jA:
7.07
5ef1N-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef1N-1l5jA:
undetectable
5ef1O-1l5jA:
undetectable		 5ef1N-1l5jA:
7.07
5ef1O-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef1O-1l5jA:
undetectable
5ef1P-1l5jA:
0.0		 5ef1O-1l5jA:
7.07
5ef1P-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef1P-1l5jA:
undetectable
5ef1Q-1l5jA:
undetectable		 5ef1P-1l5jA:
7.07
5ef1Q-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef1Q-1l5jA:
0.0
5ef1R-1l5jA:
0.0		 5ef1Q-1l5jA:
7.07
5ef1R-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef1R-1l5jA:
undetectable
5ef1S-1l5jA:
undetectable		 5ef1R-1l5jA:
7.07
5ef1S-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef1S-1l5jA:
undetectable
5ef1T-1l5jA:
undetectable		 5ef1S-1l5jA:
7.07
5ef1T-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef1T-1l5jA:
undetectable
5ef1U-1l5jA:
undetectable		 5ef1T-1l5jA:
7.07
5ef1U-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 5ef1U-1l5jA:
undetectable
5ef1V-1l5jA:
undetectable		 5ef1U-1l5jA:
7.07
5ef1V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef2B-1l5jA:
0.0
5ef2C-1l5jA:
0.0		 5ef2B-1l5jA:
7.07
5ef2C-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef2C-1l5jA:
0.0
5ef2D-1l5jA:
0.0		 5ef2C-1l5jA:
7.07
5ef2D-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5ef2D-1l5jA:
0.0
5ef2E-1l5jA:
0.0		 5ef2D-1l5jA:
7.07
5ef2E-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef2E-1l5jA:
0.0
5ef2F-1l5jA:
0.0		 5ef2E-1l5jA:
7.07
5ef2F-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5ef2F-1l5jA:
undetectable
5ef2G-1l5jA:
0.0		 5ef2F-1l5jA:
7.07
5ef2G-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef2G-1l5jA:
0.0
5ef2H-1l5jA:
0.0		 5ef2G-1l5jA:
7.07
5ef2H-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef2H-1l5jA:
0.0
5ef2I-1l5jA:
0.0		 5ef2H-1l5jA:
7.07
5ef2I-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef2I-1l5jA:
0.0
5ef2J-1l5jA:
0.0		 5ef2I-1l5jA:
7.07
5ef2J-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef2J-1l5jA:
0.0
5ef2K-1l5jA:
0.0		 5ef2J-1l5jA:
7.07
5ef2K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5ef2A-1l5jA:
0.0
5ef2K-1l5jA:
0.0		 5ef2A-1l5jA:
7.07
5ef2K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 8 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.10A 5ef2L-1l5jA:
undetectable
5ef2V-1l5jA:
undetectable		 5ef2L-1l5jA:
7.07
5ef2V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef2L-1l5jA:
0.0
5ef2M-1l5jA:
0.0		 5ef2L-1l5jA:
7.07
5ef2M-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5ef2M-1l5jA:
0.0
5ef2N-1l5jA:
0.0		 5ef2M-1l5jA:
7.07
5ef2N-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef2N-1l5jA:
undetectable
5ef2O-1l5jA:
undetectable		 5ef2N-1l5jA:
7.07
5ef2O-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef2O-1l5jA:
undetectable
5ef2P-1l5jA:
0.0		 5ef2O-1l5jA:
7.07
5ef2P-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef2P-1l5jA:
undetectable
5ef2Q-1l5jA:
undetectable		 5ef2P-1l5jA:
7.07
5ef2Q-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef2Q-1l5jA:
0.0
5ef2R-1l5jA:
0.0		 5ef2Q-1l5jA:
7.07
5ef2R-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef2R-1l5jA:
undetectable
5ef2S-1l5jA:
undetectable		 5ef2R-1l5jA:
7.07
5ef2S-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef2S-1l5jA:
undetectable
5ef2T-1l5jA:
undetectable		 5ef2S-1l5jA:
7.07
5ef2T-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef2T-1l5jA:
undetectable
5ef2U-1l5jA:
undetectable		 5ef2T-1l5jA:
7.07
5ef2U-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 5ef2U-1l5jA:
undetectable
5ef2V-1l5jA:
undetectable		 5ef2U-1l5jA:
7.07
5ef2V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef3B-1l5jA:
0.0
5ef3C-1l5jA:
0.0		 5ef3B-1l5jA:
7.07
5ef3C-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef3C-1l5jA:
0.0
5ef3D-1l5jA:
0.0		 5ef3C-1l5jA:
7.07
5ef3D-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.18A 5ef3D-1l5jA:
0.0
5ef3E-1l5jA:
0.0		 5ef3D-1l5jA:
7.07
5ef3E-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef3E-1l5jA:
0.0
5ef3F-1l5jA:
0.0		 5ef3E-1l5jA:
7.07
5ef3F-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.13A 5ef3F-1l5jA:
0.0
5ef3G-1l5jA:
0.0		 5ef3F-1l5jA:
7.07
5ef3G-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef3G-1l5jA:
0.0
5ef3H-1l5jA:
0.0		 5ef3G-1l5jA:
7.07
5ef3H-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.15A 5ef3H-1l5jA:
0.0
5ef3I-1l5jA:
0.0		 5ef3H-1l5jA:
7.07
5ef3I-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 11 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.12A 5ef3I-1l5jA:
0.0
5ef3J-1l5jA:
0.0		 5ef3I-1l5jA:
7.07
5ef3J-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 THR A 417
SER A 245
GLY A 412
ALA A 510
THR A 500
 TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
None
None
None
 1.14A 5ef3J-1l5jA:
0.0
5ef3K-1l5jA:
0.0		 5ef3J-1l5jA:
7.07
5ef3K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.14A 5ef3A-1l5jA:
undetectable
5ef3K-1l5jA:
0.0		 5ef3A-1l5jA:
7.07
5ef3K-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef3L-1l5jA:
0.0
5ef3M-1l5jA:
0.0		 5ef3L-1l5jA:
7.07
5ef3M-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.07A 5ef3M-1l5jA:
0.0
5ef3N-1l5jA:
0.0		 5ef3M-1l5jA:
7.07
5ef3N-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef3N-1l5jA:
undetectable
5ef3O-1l5jA:
undetectable		 5ef3N-1l5jA:
7.07
5ef3O-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef3O-1l5jA:
0.0
5ef3P-1l5jA:
undetectable		 5ef3O-1l5jA:
7.07
5ef3P-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef3P-1l5jA:
undetectable
5ef3Q-1l5jA:
undetectable		 5ef3P-1l5jA:
7.07
5ef3Q-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.08A 5ef3Q-1l5jA:
0.0
5ef3R-1l5jA:
0.0		 5ef3Q-1l5jA:
7.07
5ef3R-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef3R-1l5jA:
undetectable
5ef3S-1l5jA:
undetectable		 5ef3R-1l5jA:
7.07
5ef3S-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.10A 5ef3S-1l5jA:
undetectable
5ef3T-1l5jA:
undetectable		 5ef3S-1l5jA:
7.07
5ef3T-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.11A 5ef3T-1l5jA:
undetectable
5ef3U-1l5jA:
undetectable		 5ef3T-1l5jA:
7.07
5ef3U-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 10 GLY A 412
ALA A 510
THR A 500
THR A 417
SER A 245
 None
None
None
TRA  A 866 (-4.0A)
TRA  A 866 (-2.6A)
 1.06A 5ef3U-1l5jA:
undetectable
5ef3V-1l5jA:
undetectable		 5ef3U-1l5jA:
7.07
5ef3V-1l5jA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5fj2A-1l5jA:
0.0
5fj2B-1l5jA:
0.0		 5fj2A-1l5jA:
20.21
5fj2B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5fj2A-1l5jA:
0.0
5fj2B-1l5jA:
0.0		 5fj2A-1l5jA:
20.21
5fj2B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5fj3A-1l5jA:
0.0
5fj3B-1l5jA:
0.0		 5fj3A-1l5jA:
20.21
5fj3B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5fj3A-1l5jA:
undetectable
5fj3B-1l5jA:
4.0		 5fj3A-1l5jA:
20.21
5fj3B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5fvqA-1l5jA:
0.0
5fvqB-1l5jA:
0.0		 5fvqA-1l5jA:
19.28
5fvqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5fvqA-1l5jA:
0.0
5fvqB-1l5jA:
0.0		 5fvqA-1l5jA:
19.28
5fvqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5fvrA-1l5jA:
0.0
5fvrB-1l5jA:
0.0		 5fvrA-1l5jA:
19.28
5fvrB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5fvrA-1l5jA:
0.0
5fvrB-1l5jA:
0.0		 5fvrA-1l5jA:
19.28
5fvrB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5fvsA-1l5jA:
0.0
5fvsB-1l5jA:
0.0		 5fvsA-1l5jA:
19.28
5fvsB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 5fvsA-1l5jA:
0.0
5fvsB-1l5jA:
0.0		 5fvsA-1l5jA:
19.28
5fvsB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5fvtA-1l5jA:
0.0
5fvtB-1l5jA:
0.0		 5fvtA-1l5jA:
19.28
5fvtB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5fvtA-1l5jA:
0.0
5fvtB-1l5jA:
0.0		 5fvtA-1l5jA:
19.28
5fvtB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 5fvuA-1l5jA:
0.0
5fvuB-1l5jA:
0.0		 5fvuA-1l5jA:
19.93
5fvuB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5fvuA-1l5jA:
0.0
5fvuB-1l5jA:
0.0		 5fvuA-1l5jA:
19.93
5fvuB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 5fvvA-1l5jA:
0.0
5fvvB-1l5jA:
0.0		 5fvvA-1l5jA:
19.93
5fvvB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.28A 5fvvA-1l5jA:
0.0
5fvvB-1l5jA:
0.0		 5fvvA-1l5jA:
19.93
5fvvB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5fvwA-1l5jA:
0.0
5fvwB-1l5jA:
0.0		 5fvwA-1l5jA:
19.93
5fvwB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 5fvwA-1l5jA:
0.0
5fvwB-1l5jA:
0.0		 5fvwA-1l5jA:
19.93
5fvwB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5fvxA-1l5jA:
0.0
5fvxB-1l5jA:
0.0		 5fvxA-1l5jA:
19.93
5fvxB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5fvyA-1l5jA:
0.0
5fvyB-1l5jA:
0.0		 5fvyA-1l5jA:
20.21
5fvyB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5fvyA-1l5jA:
0.0
5fvyB-1l5jA:
0.0		 5fvyA-1l5jA:
20.21
5fvyB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5fvzA-1l5jA:
0.0
5fvzB-1l5jA:
0.0		 5fvzA-1l5jA:
20.21
5fvzB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5fvzA-1l5jA:
0.0
5fvzB-1l5jA:
0.0		 5fvzA-1l5jA:
20.21
5fvzB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5fw0A-1l5jA:
0.0
5fw0B-1l5jA:
0.0		 5fw0A-1l5jA:
19.28
5fw0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5fw0A-1l5jA:
0.0
5fw0B-1l5jA:
0.0		 5fw0A-1l5jA:
19.28
5fw0B-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5g0nA-1l5jA:
0.0
5g0nB-1l5jA:
0.0		 5g0nA-1l5jA:
19.05
5g0nB-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5g0nA-1l5jA:
0.0
5g0nB-1l5jA:
0.0		 5g0nA-1l5jA:
19.05
5g0nB-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5g0oA-1l5jA:
0.0
5g0oB-1l5jA:
0.0		 5g0oA-1l5jA:
19.05
5g0oB-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5g0oA-1l5jA:
0.0
5g0oB-1l5jA:
0.0		 5g0oA-1l5jA:
19.05
5g0oB-1l5jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ARG A 796
SER A 512
ASP A 288
ARG A 344
GLY A 243
 TRA  A 866 (-2.9A)
None
None
None
None
 1.16A 5hikA-1l5jA:
undetectable		 5hikA-1l5jA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 ILE A 581
ASP A 689
VAL A 550
GLY A 243
THR A 242
 None
 1.18A 5igiA-1l5jA:
0.0		 5igiA-1l5jA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 TYR A 754
TYR A 448
SER A 770
 None
 0.76A 5iktB-1l5jA:
0.0		 5iktB-1l5jA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 LEU A 579
CYH A 607
GLY A 606
LEU A 595
MET A 711
 None
 1.43A 5kklB-1l5jA:
0.0		 5kklB-1l5jA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.76A 5kqxA-1l5jA:
undetectable		 5kqxA-1l5jA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 LEU A 361
ALA A 357
LEU A 363
THR A 354
 None
 0.89A 5l4iA-1l5jA:
undetectable		 5l4iA-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 GLY A 275
VAL A 236
ALA A 234
LEU A 272
VAL A 316
 None
 1.06A 5lw1H-1l5jA:
undetectable		 5lw1H-1l5jA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 12 GLY A 721
ALA A 720
GLY A 715
ILE A 714
ILE A 707
 None
 0.81A 5t8hA-1l5jA:
undetectable		 5t8hA-1l5jA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 GLY A 513
ARG A 344
MET A 420
GLN A 440
 None
 1.36A 5ubbA-1l5jA:
undetectable		 5ubbA-1l5jA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5unsA-1l5jA:
0.0
5unsB-1l5jA:
0.0		 5unsA-1l5jA:
19.28
5unsB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5unsA-1l5jA:
0.0
5unsB-1l5jA:
0.0		 5unsA-1l5jA:
19.28
5unsB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5untA-1l5jA:
0.0
5untB-1l5jA:
0.0		 5untA-1l5jA:
19.28
5untB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5untA-1l5jA:
0.0
5untB-1l5jA:
0.0		 5untA-1l5jA:
19.28
5untB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5unuA-1l5jA:
0.0
5unuB-1l5jA:
0.0		 5unuA-1l5jA:
19.28
5unuB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.25A 5unvA-1l5jA:
0.0
5unvB-1l5jA:
0.0		 5unvA-1l5jA:
19.28
5unvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5unvA-1l5jA:
0.0
5unvB-1l5jA:
0.0		 5unvA-1l5jA:
19.28
5unvB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5unyA-1l5jA:
0.0
5unyB-1l5jA:
0.0		 5unyA-1l5jA:
19.28
5unyB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5uo1A-1l5jA:
0.0
5uo1B-1l5jA:
0.0		 5uo1A-1l5jA:
19.93
5uo1B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 5uo2A-1l5jA:
0.0
5uo2B-1l5jA:
0.0		 5uo2A-1l5jA:
19.93
5uo2B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5uo2A-1l5jA:
0.0
5uo2B-1l5jA:
0.0		 5uo2A-1l5jA:
19.93
5uo2B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5uo3A-1l5jA:
0.0
5uo3B-1l5jA:
0.0		 5uo3A-1l5jA:
19.93
5uo3B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5uo4A-1l5jA:
undetectable
5uo4B-1l5jA:
undetectable		 5uo4A-1l5jA:
19.93
5uo4B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5uo4A-1l5jA:
0.0
5uo4B-1l5jA:
0.0		 5uo4A-1l5jA:
19.93
5uo4B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5uo5A-1l5jA:
0.0
5uo5B-1l5jA:
0.0		 5uo5A-1l5jA:
19.93
5uo5B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 5uo5A-1l5jA:
0.0
5uo5B-1l5jA:
0.0		 5uo5A-1l5jA:
19.93
5uo5B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 5uo8A-1l5jA:
0.0
5uo8B-1l5jA:
0.0		 5uo8A-1l5jA:
20.71
5uo8B-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 5uo8A-1l5jA:
0.0
5uo8B-1l5jA:
0.0		 5uo8A-1l5jA:
20.71
5uo8B-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5uo8C-1l5jA:
0.0
5uo8D-1l5jA:
0.0		 5uo8C-1l5jA:
20.71
5uo8D-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5uo8C-1l5jA:
0.0
5uo8D-1l5jA:
0.0		 5uo8C-1l5jA:
20.71
5uo8D-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.37A 5uo9A-1l5jA:
0.0
5uo9B-1l5jA:
0.0		 5uo9A-1l5jA:
20.71
5uo9B-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 5uo9A-1l5jA:
0.0
5uo9B-1l5jA:
0.0		 5uo9A-1l5jA:
20.71
5uo9B-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5uo9C-1l5jA:
0.2
5uo9D-1l5jA:
0.0		 5uo9C-1l5jA:
20.71
5uo9D-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 5uo9C-1l5jA:
0.0
5uo9D-1l5jA:
0.0		 5uo9C-1l5jA:
20.71
5uo9D-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5uodA-1l5jA:
0.0
5uodB-1l5jA:
0.0		 5uodA-1l5jA:
20.21
5uodB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5uodA-1l5jA:
0.0
5uodB-1l5jA:
0.0		 5uodA-1l5jA:
20.21
5uodB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5vuiA-1l5jA:
0.0
5vuiB-1l5jA:
0.0		 5vuiA-1l5jA:
19.28
5vuiB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.24A 5vujA-1l5jA:
0.0
5vujB-1l5jA:
0.0		 5vujA-1l5jA:
19.28
5vujB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.29A 5vujA-1l5jA:
0.0
5vujB-1l5jA:
0.0		 5vujA-1l5jA:
19.28
5vujB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5vukA-1l5jA:
0.0
5vukB-1l5jA:
0.0		 5vukA-1l5jA:
19.28
5vukB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vulA-1l5jA:
0.0
5vulB-1l5jA:
0.0		 5vulA-1l5jA:
19.28
5vulB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5vulA-1l5jA:
0.0
5vulB-1l5jA:
0.0		 5vulA-1l5jA:
19.28
5vulB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5vumA-1l5jA:
0.0
5vumB-1l5jA:
0.0		 5vumA-1l5jA:
19.28
5vumB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vumA-1l5jA:
0.0
5vumB-1l5jA:
0.0		 5vumA-1l5jA:
19.28
5vumB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5vunA-1l5jA:
0.0
5vunB-1l5jA:
0.0		 5vunA-1l5jA:
19.28
5vunB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vunA-1l5jA:
0.0
5vunB-1l5jA:
0.0		 5vunA-1l5jA:
19.28
5vunB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 5vuoA-1l5jA:
0.0
5vuoB-1l5jA:
0.0		 5vuoA-1l5jA:
19.28
5vuoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 5vuoA-1l5jA:
0.0
5vuoB-1l5jA:
0.0		 5vuoA-1l5jA:
19.28
5vuoB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vupA-1l5jA:
0.0
5vupB-1l5jA:
0.0		 5vupA-1l5jA:
19.28
5vupB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vupA-1l5jA:
0.0
5vupB-1l5jA:
0.0		 5vupA-1l5jA:
19.28
5vupB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vuqA-1l5jA:
0.0
5vuqB-1l5jA:
0.0		 5vuqA-1l5jA:
19.28
5vuqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5vuqA-1l5jA:
0.0
5vuqB-1l5jA:
0.0		 5vuqA-1l5jA:
19.28
5vuqB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vusA-1l5jA:
0.0
5vusB-1l5jA:
0.0		 5vusA-1l5jA:
19.28
5vusB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5vutA-1l5jA:
0.0
5vutB-1l5jA:
0.0		 5vutA-1l5jA:
19.28
5vutB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 5vutA-1l5jA:
0.0
5vutB-1l5jA:
0.0		 5vutA-1l5jA:
19.28
5vutB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vuuA-1l5jA:
0.0
5vuuB-1l5jA:
0.0		 5vuuA-1l5jA:
19.28
5vuuB-1l5jA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vuvA-1l5jA:
0.0
5vuvB-1l5jA:
0.0		 5vuvA-1l5jA:
19.93
5vuvB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5vuvA-1l5jA:
0.0
5vuvB-1l5jA:
0.0		 5vuvA-1l5jA:
19.93
5vuvB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vuwA-1l5jA:
0.0
5vuwB-1l5jA:
0.0		 5vuwA-1l5jA:
19.93
5vuwB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5vuwA-1l5jA:
0.0
5vuwB-1l5jA:
0.0		 5vuwA-1l5jA:
19.93
5vuwB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vuxA-1l5jA:
0.0
5vuxB-1l5jA:
0.0		 5vuxA-1l5jA:
19.93
5vuxB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5vuyA-1l5jA:
0.0
5vuyB-1l5jA:
0.0		 5vuyA-1l5jA:
19.93
5vuyB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vuzA-1l5jA:
0.0
5vuzB-1l5jA:
0.0		 5vuzA-1l5jA:
19.93
5vuzB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5vuzA-1l5jA:
0.0
5vuzB-1l5jA:
0.0		 5vuzA-1l5jA:
19.93
5vuzB-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vv0A-1l5jA:
0.0
5vv0B-1l5jA:
0.0		 5vv0A-1l5jA:
19.35
5vv0B-1l5jA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vv0A-1l5jA:
0.0
5vv0B-1l5jA:
0.0		 5vv0A-1l5jA:
19.35
5vv0B-1l5jA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 5vv1A-1l5jA:
0.0
5vv1B-1l5jA:
0.0		 5vv1A-1l5jA:
19.93
5vv1B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5vv1A-1l5jA:
0.0
5vv1B-1l5jA:
0.0		 5vv1A-1l5jA:
19.93
5vv1B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vv2A-1l5jA:
0.0
5vv2B-1l5jA:
0.0		 5vv2A-1l5jA:
19.93
5vv2B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 5vv2A-1l5jA:
0.0
5vv2B-1l5jA:
0.0		 5vv2A-1l5jA:
19.93
5vv2B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 5vv3A-1l5jA:
0.0
5vv3B-1l5jA:
0.0		 5vv3A-1l5jA:
19.93
5vv3B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vv4A-1l5jA:
0.0
5vv4B-1l5jA:
0.0		 5vv4A-1l5jA:
19.93
5vv4B-1l5jA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vv6A-1l5jA:
0.0
5vv6B-1l5jA:
0.0		 5vv6A-1l5jA:
20.21
5vv6B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 5vv6A-1l5jA:
0.0
5vv6B-1l5jA:
0.0		 5vv6A-1l5jA:
20.21
5vv6B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vv7A-1l5jA:
0.0
5vv7B-1l5jA:
0.0		 5vv7A-1l5jA:
20.21
5vv7B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5vv7A-1l5jA:
undetectable
5vv7B-1l5jA:
3.9		 5vv7A-1l5jA:
20.21
5vv7B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vv8A-1l5jA:
0.0
5vv8B-1l5jA:
0.0		 5vv8A-1l5jA:
20.21
5vv8B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 5vv8A-1l5jA:
0.0
5vv8B-1l5jA:
0.0		 5vv8A-1l5jA:
20.21
5vv8B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.40A 5vv9A-1l5jA:
0.0
5vv9B-1l5jA:
0.0		 5vv9A-1l5jA:
20.21
5vv9B-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.38A 5vvaA-1l5jA:
0.0
5vvaB-1l5jA:
0.0		 5vvaA-1l5jA:
20.21
5vvaB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.41A 5vvaA-1l5jA:
0.0
5vvaB-1l5jA:
0.0		 5vvaA-1l5jA:
20.21
5vvaB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vvbA-1l5jA:
0.0
5vvbB-1l5jA:
0.0		 5vvbA-1l5jA:
20.71
5vvbB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vvbA-1l5jA:
0.0
5vvbB-1l5jA:
0.0		 5vvbA-1l5jA:
20.71
5vvbB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.38A 5vvbC-1l5jA:
0.0
5vvbD-1l5jA:
0.0		 5vvbC-1l5jA:
20.71
5vvbD-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vvbC-1l5jA:
0.0
5vvbD-1l5jA:
0.0		 5vvbC-1l5jA:
20.71
5vvbD-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.37A 5vvcA-1l5jA:
0.0
5vvcB-1l5jA:
0.0		 5vvcA-1l5jA:
20.71
5vvcB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 5vvcA-1l5jA:
0.0
5vvcB-1l5jA:
0.0		 5vvcA-1l5jA:
20.71
5vvcB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 5vvcC-1l5jA:
0.0
5vvcD-1l5jA:
0.4		 5vvcC-1l5jA:
20.71
5vvcD-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 5vvcC-1l5jA:
0.0
5vvcD-1l5jA:
0.4		 5vvcC-1l5jA:
20.71
5vvcD-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 5 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 5vvdA-1l5jA:
0.0
5vvdB-1l5jA:
0.0		 5vvdA-1l5jA:
20.71
5vvdB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5vvdA-1l5jA:
0.0
5vvdB-1l5jA:
0.0		 5vvdA-1l5jA:
20.71
5vvdB-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 5vvdC-1l5jA:
0.0
5vvdD-1l5jA:
0.0		 5vvdC-1l5jA:
20.71
5vvdD-1l5jA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vvgA-1l5jA:
0.0
5vvgB-1l5jA:
0.0		 5vvgA-1l5jA:
20.21
5vvgB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 5vvgA-1l5jA:
0.0
5vvgB-1l5jA:
0.0		 5vvgA-1l5jA:
20.21
5vvgB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 5vvnA-1l5jA:
0.0
5vvnB-1l5jA:
0.0		 5vvnA-1l5jA:
20.21
5vvnB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.37A 5vvnA-1l5jA:
undetectable
5vvnB-1l5jA:
undetectable		 5vvnA-1l5jA:
20.21
5vvnB-1l5jA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		3 / 3 TYR A 841
ARG A 718
THR A 836
 None
 0.97A 5z84J-1l5jA:
0.0		 5z84J-1l5jA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6auqA-1l5jA:
0.0
6auqB-1l5jA:
0.0		 6auqA-1l5jA:
6.89
6auqB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6aurA-1l5jA:
0.0
6aurB-1l5jA:
0.0		 6aurA-1l5jA:
6.89
6aurB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.33A 6aurA-1l5jA:
0.0
6aurB-1l5jA:
0.0		 6aurA-1l5jA:
6.89
6aurB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.33A 6ausA-1l5jA:
0.0
6ausB-1l5jA:
0.0		 6ausA-1l5jA:
6.89
6ausB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6ausA-1l5jA:
0.0
6ausB-1l5jA:
0.0		 6ausA-1l5jA:
6.89
6ausB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6autA-1l5jA:
0.0
6autB-1l5jA:
0.0		 6autA-1l5jA:
6.89
6autB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 6autA-1l5jA:
0.0
6autB-1l5jA:
0.0		 6autA-1l5jA:
6.89
6autB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 6auuA-1l5jA:
0.0
6auuB-1l5jA:
0.0		 6auuA-1l5jA:
6.89
6auuB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6auvA-1l5jA:
0.0
6auvB-1l5jA:
0.0		 6auvA-1l5jA:
6.89
6auvB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 6auvA-1l5jA:
0.0
6auvB-1l5jA:
0.0		 6auvA-1l5jA:
6.89
6auvB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.31A 6auwA-1l5jA:
0.0
6auwB-1l5jA:
0.0		 6auwA-1l5jA:
6.89
6auwB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 6auwA-1l5jA:
0.0
6auwB-1l5jA:
0.0		 6auwA-1l5jA:
6.89
6auwB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 6auxA-1l5jA:
0.0
6auxB-1l5jA:
0.0		 6auxA-1l5jA:
6.89
6auxB-1l5jA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 6auyA-1l5jA:
0.0
6auyB-1l5jA:
0.0		 6auyA-1l5jA:
5.96
6auyB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 6auyA-1l5jA:
0.0
6auyB-1l5jA:
0.0		 6auyA-1l5jA:
5.96
6auyB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6auzA-1l5jA:
0.0
6auzB-1l5jA:
0.0		 6auzA-1l5jA:
5.96
6auzB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 6auzA-1l5jA:
0.0
6auzB-1l5jA:
0.0		 6auzA-1l5jA:
5.96
6auzB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 6av0A-1l5jA:
0.0
6av0B-1l5jA:
0.0		 6av0A-1l5jA:
5.96
6av0B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6av0A-1l5jA:
0.0
6av0B-1l5jA:
0.0		 6av0A-1l5jA:
5.96
6av0B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6av3A-1l5jA:
0.0
6av3B-1l5jA:
0.0		 6av3A-1l5jA:
5.96
6av3B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 6av3A-1l5jA:
0.0
6av3B-1l5jA:
0.0		 6av3A-1l5jA:
5.96
6av3B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6av4A-1l5jA:
0.0
6av4B-1l5jA:
0.0		 6av4A-1l5jA:
5.96
6av4B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 6av4A-1l5jA:
0.0
6av4B-1l5jA:
0.0		 6av4A-1l5jA:
5.96
6av4B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 6av5A-1l5jA:
0.0
6av5B-1l5jA:
0.0		 6av5A-1l5jA:
5.96
6av5B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 6av5A-1l5jA:
0.0
6av5B-1l5jA:
0.0		 6av5A-1l5jA:
5.96
6av5B-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 6av6A-1l5jA:
0.0
6av6B-1l5jA:
0.0		 6av6A-1l5jA:
7.08
6av6B-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.30A 6av6A-1l5jA:
0.0
6av6B-1l5jA:
0.0		 6av6A-1l5jA:
7.08
6av6B-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.29A 6av6C-1l5jA:
0.0
6av6D-1l5jA:
0.0		 6av6C-1l5jA:
7.08
6av6D-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 6av6C-1l5jA:
0.0
6av6D-1l5jA:
0.0		 6av6C-1l5jA:
7.08
6av6D-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.36A 6av7A-1l5jA:
undetectable
6av7B-1l5jA:
undetectable		 6av7A-1l5jA:
7.08
6av7B-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6av7A-1l5jA:
0.0
6av7B-1l5jA:
0.0		 6av7A-1l5jA:
7.08
6av7B-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.32A 6av7C-1l5jA:
0.0
6av7D-1l5jA:
0.0		 6av7C-1l5jA:
7.08
6av7D-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6av7C-1l5jA:
0.0
6av7D-1l5jA:
0.0		 6av7C-1l5jA:
7.08
6av7D-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 ILE A 764
PHE A 717
GLY A 721
PHE A 757
GLY A 758
 None
 1.35A 6awoA-1l5jA:
undetectable		 6awoA-1l5jA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		5 / 9 ILE A 764
PHE A 717
GLY A 721
PHE A 757
GLY A 758
 None
 1.35A 6awqA-1l5jA:
undetectable		 6awqA-1l5jA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 6cicA-1l5jA:
0.0
6cicB-1l5jA:
0.0		 6cicA-1l5jA:
5.96
6cicB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.32A 6cicA-1l5jA:
0.0
6cicB-1l5jA:
0.0		 6cicA-1l5jA:
5.96
6cicB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.34A 6cidA-1l5jA:
0.0
6cidB-1l5jA:
0.0		 6cidA-1l5jA:
5.96
6cidB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6cidA-1l5jA:
0.0
6cidB-1l5jA:
0.0		 6cidA-1l5jA:
5.96
6cidB-1l5jA:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.37A 6cieA-1l5jA:
0.0
6cieB-1l5jA:
0.0		 6cieA-1l5jA:
7.08
6cieB-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 7 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6cieA-1l5jA:
0.0
6cieB-1l5jA:
0.0		 6cieA-1l5jA:
7.08
6cieB-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.30A 6cieC-1l5jA:
0.0
6cieD-1l5jA:
0.0		 6cieC-1l5jA:
7.08
6cieD-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.35A 6cieC-1l5jA:
0.0
6cieD-1l5jA:
0.0		 6cieC-1l5jA:
7.08
6cieD-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.36A 6cifA-1l5jA:
0.0
6cifB-1l5jA:
0.0		 6cifA-1l5jA:
7.08
6cifB-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.34A 6cifC-1l5jA:
0.0
6cifD-1l5jA:
0.0		 6cifC-1l5jA:
7.08
6cifD-1l5jA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 LEU A 347
VAL A 375
PHE A 369
GLY A 352
 None
 0.85A 6hd4B-1l5jA:
undetectable		 6hd4B-1l5jA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 8 ALA A 518
GLY A 513
LEU A 514
ALA A 510
 None
 0.71A 6mdqA-1l5jA:
2.4		 6mdqA-1l5jA:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 ARG A 340
TRP A 155
PHE A 156
GLU A 154
 None
 1.35A 8nseA-1l5jA:
0.0
8nseB-1l5jA:
0.0		 8nseA-1l5jA:
20.09
8nseB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 8nseA-1l5jA:
0.0
8nseB-1l5jA:
0.0		 8nseA-1l5jA:
20.09
8nseB-1l5jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l5j ACONITATE HYDRATASE
2
(Escherichia
coli) 		4 / 6 TRP A 155
PHE A 156
GLU A 154
ARG A 340
 None
 1.31A 9nseA-1l5jA:
0.0
9nseB-1l5jA:
0.0		 9nseA-1l5jA:
20.09
9nseB-1l5jA:
20.09