SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9S_C_BEZC264_0 (CARNITINYL-COA DEHYDRATASE)	1l5z	C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD (Sinorhizobium meliloti)	4 / 6	ALA A 116 ILE A 53 LEU A 112 ALA A 27	None	0.90A	3r9sC-1l5zA: undetectable	3r9sC-1l5zA: 23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_C_SVRC516_1 (RNA-DEPENDENT RNA POLYMERASE)	1l5z	C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD (Sinorhizobium meliloti)	5 / 9	GLY A 50 ALA A 49 ALA A 46 ASP A 47 ARG A 130	None	1.21A	3ur0C-1l5zA: 0.0	3ur0C-1l5zA: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA605_0 (ALPHA-AMYLASE)	1l5z	C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD (Sinorhizobium meliloti)	4 / 8	GLY A 50 ILE A 51 ASP A 74 ASP A 76	None	0.87A	6ag0A-1l5zA: undetectable	6ag0A-1l5zA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC605_0 (ALPHA-AMYLASE)	1l5z	C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD (Sinorhizobium meliloti)	4 / 8	GLY A 50 ILE A 51 ASP A 74 ASP A 76	None	0.91A	6ag0C-1l5zA: undetectable	6ag0C-1l5zA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3R9S_C_BEZC264_0","CARNITINYL-COA DEHYDRATASE","1l5z","C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD","Sinorhizobium meliloti",4,"ALA A 116;ILE A  53;LEU A 112;ALA A  27","None","0.90A","3r9sC-1l5zA:undetectable","3r9sC-1l5zA:23.51"],["3UR0_C_SVRC516_1","RNA-DEPENDENT RNA POLYMERASE","1l5z","C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD","Sinorhizobium meliloti",5,"GLY A  50;ALA A  49;ALA A  46;ASP A  47;ARG A 130","None","1.21A","3ur0C-1l5zA:0.0","3ur0C-1l5zA:17.09"],["6AG0_A_ACRA605_0","ALPHA-AMYLASE","1l5z","C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD","Sinorhizobium meliloti",4,"GLY A  50;ILE A  51;ASP A  74;ASP A  76","None","0.87A","6ag0A-1l5zA:undetectable","6ag0A-1l5zA:20.00"],["6AG0_C_ACRC605_0","ALPHA-AMYLASE","1l5z","C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD","Sinorhizobium meliloti",4,"GLY A  50;ILE A  51;ASP A  74;ASP A  76","None","0.91A","6ag0C-1l5zA:undetectable","6ag0C-1l5zA:20.00"]]