SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1l8r DACHSHUND
(Homo
sapiens) 		6 / 12 LEU A 219
VAL A 229
LEU A 208
ILE A 267
LEU A 233
LYS A 232
 None
 1.30A 4y0qA-1l8rA:
undetectable		 4y0qA-1l8rA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1l8r DACHSHUND
(Homo
sapiens) 		5 / 10 VAL A 198
ILE A 209
ARG A 194
GLY A 195
ALA A 196
 None
 1.00A 5mxbA-1l8rA:
undetectable		 5mxbA-1l8rA:
22.22