SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l8w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 SER A 315
GLY A 307
ALA A 313
ILE A 309
 None
 0.69A 1c9sI-1l8wA:
undetectable
1c9sJ-1l8wA:
undetectable		 1c9sI-1l8wA:
11.14
1c9sJ-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.73A 1c9sU-1l8wA:
undetectable
1c9sV-1l8wA:
undetectable		 1c9sU-1l8wA:
11.14
1c9sV-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.98A 1eqhA-1l8wA:
undetectable		 1eqhA-1l8wA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.93A 1eqhB-1l8wA:
undetectable		 1eqhB-1l8wA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 7 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.66A 1gtnA-1l8wA:
undetectable
1gtnK-1l8wA:
undetectable		 1gtnA-1l8wA:
11.14
1gtnK-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 SER A 315
GLY A 307
ALA A 313
ILE A 309
 None
 0.70A 1gtnA-1l8wA:
undetectable
1gtnB-1l8wA:
undetectable		 1gtnA-1l8wA:
11.14
1gtnB-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 SER A 315
GLY A 307
ALA A 313
ILE A 309
 None
 0.69A 1gtnE-1l8wA:
undetectable
1gtnF-1l8wA:
undetectable		 1gtnE-1l8wA:
11.14
1gtnF-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 SER A 315
GLY A 307
ALA A 313
ILE A 309
 None
 0.65A 1gtnI-1l8wA:
undetectable
1gtnJ-1l8wA:
undetectable		 1gtnI-1l8wA:
11.14
1gtnJ-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.78A 1gtnP-1l8wA:
undetectable
1gtnQ-1l8wA:
undetectable		 1gtnP-1l8wA:
11.14
1gtnQ-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 ILE A 328
ALA A  78
SER A 140
ILE A 167
ILE A 324
 None
 1.31A 1j3jA-1l8wA:
undetectable		 1j3jA-1l8wA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 9 ILE A 284
PHE A 202
GLY A 199
ILE A 280
ALA A 222
 None
 1.24A 1mrgA-1l8wA:
undetectable		 1mrgA-1l8wA:
25.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 11 GLY A 221
ALA A 222
ASP A 277
GLY A 197
ILE A 284
 None
 0.90A 1ohrA-1l8wA:
undetectable		 1ohrA-1l8wA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 LEU A 321
ILE A 171
SER A 140
VAL A  77
LEU A 129
 None
 1.15A 1s19A-1l8wA:
0.0		 1s19A-1l8wA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 8 ALA A 290
GLY A 166
ILE A 171
PRO A 255
ALA A 283
 None
 1.08A 1sguA-1l8wA:
undetectable		 1sguA-1l8wA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.66A 1utdB-1l8wA:
undetectable
1utdC-1l8wA:
undetectable		 1utdB-1l8wA:
11.14
1utdC-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.70A 1utdF-1l8wA:
undetectable
1utdG-1l8wA:
undetectable		 1utdF-1l8wA:
11.14
1utdG-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.70A 1utdI-1l8wA:
undetectable
1utdJ-1l8wA:
undetectable		 1utdI-1l8wA:
11.14
1utdJ-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 GLY A 307
ALA A 313
ILE A 309
SER A 315
 None
 0.70A 1utdJ-1l8wA:
undetectable
1utdK-1l8wA:
undetectable		 1utdJ-1l8wA:
11.14
1utdK-1l8wA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 7 VAL A  70
PHE A  74
THR A  76
LYS A 134
 None
 1.23A 2kotA-1l8wA:
undetectable		 2kotA-1l8wA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 ALA A 139
VAL A  70
PHE A  74
THR A  75
 None
 0.99A 2kotB-1l8wA:
undetectable		 2kotB-1l8wA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 5 ALA A 238
ALA A 285
ALA A 316
VAL A 226
 None
 0.91A 2nyrB-1l8wA:
undetectable		 2nyrB-1l8wA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 6 LEU A 129
VAL A 133
LYS A 134
ILE A 174
 None
 0.83A 2piwA-1l8wA:
undetectable		 2piwA-1l8wA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 GLY A 221
ALA A 222
ASP A 277
GLY A 197
ILE A 284
 None
 0.86A 2q63A-1l8wA:
undetectable		 2q63A-1l8wA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 GLY A 221
ALA A 222
ASP A 277
GLY A 197
ILE A 284
 None
 0.89A 2z54B-1l8wA:
undetectable		 2z54B-1l8wA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 ILE A 174
PHE A  74
ALA A  78
VAL A 236
ILE A 235
 None
 1.02A 3e00A-1l8wA:
undetectable		 3e00A-1l8wA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 ALA A 290
ASP A 160
ILE A 171
PRO A 255
ALA A 283
 None
 0.96A 3ekpB-1l8wA:
undetectable		 3ekpB-1l8wA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 ALA A 290
ASP A 160
ILE A 171
PRO A 255
ALA A 283
 None
 0.98A 3ekpC-1l8wA:
undetectable		 3ekpC-1l8wA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 GLY A 221
ALA A 222
ASP A 277
GLY A 197
ILE A 284
 None
 0.91A 3ekqA-1l8wA:
undetectable		 3ekqA-1l8wA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 9 ALA A 290
ASP A 160
ILE A 171
PRO A 255
ALA A 283
 None
 1.01A 3ektB-1l8wA:
undetectable		 3ektB-1l8wA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 11 GLY A 221
ALA A 222
ASP A 277
GLY A 197
ILE A 284
 None
 0.83A 3ekxA-1l8wA:
undetectable		 3ekxA-1l8wA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 ILE A 174
PHE A  74
ALA A  78
VAL A 236
ILE A 235
 None
 1.04A 3falA-1l8wA:
undetectable		 3falA-1l8wA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 SER A 163
GLY A 288
GLY A 293
LEU A 286
VAL A  70
 None
 1.14A 3fzgA-1l8wA:
undetectable		 3fzgA-1l8wA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 GLY A 221
ALA A 222
ASP A 277
GLY A 197
ILE A 284
 None
 0.82A 3jw2B-1l8wA:
undetectable		 3jw2B-1l8wA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.95A 3n8wA-1l8wA:
undetectable		 3n8wA-1l8wA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.95A 3n8zA-1l8wA:
undetectable		 3n8zA-1l8wA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 11 GLU A 229
GLY A 326
ALA A 323
ILE A 328
ALA A 331
 None
 1.17A 3nmuB-1l8wA:
1.7
3nmuJ-1l8wA:
undetectable		 3nmuB-1l8wA:
25.70
3nmuJ-1l8wA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.93A 3pghC-1l8wA:
undetectable		 3pghC-1l8wA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 ILE A 328
ALA A  78
SER A 140
ILE A 167
ILE A 324
 None
 1.32A 3qgtA-1l8wA:
undetectable		 3qgtA-1l8wA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 6 ALA A 168
ILE A 256
LEU A 286
ALA A 139
 None
 0.78A 3r9sA-1l8wA:
undetectable		 3r9sA-1l8wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 6 ALA A 168
ILE A 256
LEU A 286
ALA A 139
 None
 0.74A 3r9sC-1l8wA:
undetectable		 3r9sC-1l8wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.92A 3rr3A-1l8wA:
undetectable		 3rr3A-1l8wA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.93A 3rr3B-1l8wA:
undetectable		 3rr3B-1l8wA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 9 ALA A 290
ASP A 160
ILE A 260
ILE A 171
PRO A 255
 None
 0.96A 3s45A-1l8wA:
undetectable		 3s45A-1l8wA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 GLY A 311
LEU A 286
GLY A 288
ALA A 281
ALA A 282
 None
 1.04A 3sufA-1l8wA:
undetectable		 3sufA-1l8wA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 1l8w VLSE1
(Borreliella
burgdorferi) 		3 / 3 LEU A  88
LYS A  85
THR A  84
 None
 0.60A 4lj0A-1l8wA:
undetectable		 4lj0A-1l8wA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 LEU A 286
ALA A 259
ASN A 254
ALA A 234
ILE A 231
 None
 0.83A 4o2bB-1l8wA:
undetectable		 4o2bB-1l8wA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 LEU A 286
ALA A 259
ASN A 254
ALA A 234
ILE A 231
 None
 0.87A 4o2bD-1l8wA:
undetectable		 4o2bD-1l8wA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 6 ILE A 284
ARG A 287
GLY A 147
VAL A 149
 None
 1.02A 4oltA-1l8wA:
0.0		 4oltA-1l8wA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 6 ILE A 284
ARG A 287
GLY A 147
VAL A 149
 None
 0.98A 4oltB-1l8wA:
0.0		 4oltB-1l8wA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.94A 4ph9A-1l8wA:
undetectable		 4ph9A-1l8wA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 10 VAL A 332
LEU A  81
GLY A 179
ALA A 178
LEU A 125
 None
 0.95A 4ph9B-1l8wA:
undetectable		 4ph9B-1l8wA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 8 ALA A 312
ALA A 313
ILE A 284
ALA A 296
 None
 0.69A 4v1fA-1l8wA:
undetectable
4v1fB-1l8wA:
undetectable		 4v1fA-1l8wA:
13.54
4v1fB-1l8wA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 9 ILE A 284
PHE A 202
GLY A 199
ILE A 280
ALA A 222
 None
 1.27A 4yp2B-1l8wA:
undetectable		 4yp2B-1l8wA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 7 ILE A 256
LEU A 286
GLY A 166
LYS A 169
 None
 0.97A 4z69A-1l8wA:
0.0		 4z69A-1l8wA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 9 ILE A 284
PHE A 202
GLY A 199
ILE A 280
ALA A 222
 None
 1.30A 5cf9B-1l8wA:
undetectable		 5cf9B-1l8wA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 LEU A 286
ALA A 259
ASN A 254
ALA A 234
ILE A 231
 None
 0.83A 5eypB-1l8wA:
undetectable		 5eypB-1l8wA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 LEU A 286
ALA A 259
ASN A 254
ALA A 234
ILE A 231
 None
 0.81A 5mioB-1l8wA:
undetectable		 5mioB-1l8wA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 ILE A 167
GLY A 170
ALA A 139
ALA A 290
VAL A  70
 None
 1.16A 5n0oB-1l8wA:
undetectable		 5n0oB-1l8wA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 ILE A 309
GLY A 147
PHE A 202
ALA A 216
VAL A 297
 None
 1.22A 5n0xB-1l8wA:
undetectable		 5n0xB-1l8wA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 PHE A  74
ILE A 324
ALA A 282
ILE A 256
GLU A 173
 None
 1.12A 5vceA-1l8wA:
0.0		 5vceA-1l8wA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		5 / 12 LEU A 286
ALA A 259
ASN A 254
ALA A 234
ILE A 231
 None
 0.90A 5xiwB-1l8wA:
undetectable		 5xiwB-1l8wA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 1l8w VLSE1
(Borreliella
burgdorferi) 		4 / 4 VAL A 158
GLY A 261
ASP A 262
ASP A 245
 None
 1.32A 6cjkC-1l8wA:
undetectable		 6cjkC-1l8wA:
20.73