SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1l9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		4 / 6 PHE A  79
GLU A  46
LEU A  22
VAL A  30
 None
DHS  A 301 (-2.6A)
None
None
 1.07A 1hk1A-1l9wA:
0.0		 1hk1A-1l9wA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		4 / 6 TRP A  47
PHE A  52
GLU A  33
ILE A  68
 None
 1.08A 1nsiA-1l9wA:
0.0
1nsiB-1l9wA:
0.0		 1nsiA-1l9wA:
21.33
1nsiB-1l9wA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		5 / 9 TYR A  97
VAL A 139
ASP A 114
ILE A 113
VAL A 138
 None
 1.45A 2l8mA-1l9wA:
0.0		 2l8mA-1l9wA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		5 / 12 ILE A  27
THR A  58
LEU A 100
PHE A  79
LEU A 109
 None
 1.06A 2qo5A-1l9wA:
undetectable		 2qo5A-1l9wA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		4 / 7 ARG A  25
PHE A  52
ILE A  27
ASN A  28
 None
 1.07A 2zseA-1l9wA:
0.0		 2zseA-1l9wA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		5 / 12 PHE A 225
SER A  21
PHE A 145
MET A 203
ALA A 172
 DHS  A 301 (-3.9A)
DHS  A 301 (-3.0A)
None
DHS  A 301 ( 4.3A)
DHS  A 301 ( 4.6A)
 1.42A 3nuvA-1l9wA:
0.0		 3nuvA-1l9wA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		3 / 3 GLN A 192
THR A 188
LEU A 249
 None
 0.67A 3ondB-1l9wA:
undetectable		 3ondB-1l9wA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		5 / 12 LEU A 115
GLY A 165
ALA A 166
VAL A   4
ILE A 113
 None
 0.91A 3s54A-1l9wA:
undetectable		 3s54A-1l9wA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		3 / 3 TYR A  97
ARG A  82
SER A  83
 None
DHS  A 301 (-4.3A)
None
 1.05A 4lf7I-1l9wA:
0.0
4lf7J-1l9wA:
undetectable		 4lf7I-1l9wA:
20.48
4lf7J-1l9wA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		3 / 3 TYR A  97
ARG A  82
SER A  83
 None
DHS  A 301 (-4.3A)
None
 1.05A 4lf8I-1l9wA:
0.0
4lf8J-1l9wA:
undetectable		 4lf8I-1l9wA:
20.48
4lf8J-1l9wA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		5 / 12 ASP A 144
THR A  91
GLN A  90
GLY A  88
GLU A  86
 None
 0.94A 5hfjC-1l9wA:
undetectable		 5hfjC-1l9wA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		4 / 7 ILE A  18
GLY A 226
LEU A 185
PHE A 219
 None
 0.85A 5hieB-1l9wA:
undetectable		 5hieB-1l9wA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 1l9w 3-DEHYDROQUINATE
DEHYDRATASE AROD
(Salmonella
enterica) 		5 / 12 LEU A  78
PRO A  76
THR A   5
ASP A  43
ILE A  19
 None
 1.05A 6emuB-1l9wA:
2.4		 6emuB-1l9wA:
21.97