SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1laj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		5 / 8 LEU A  90
ILE A 202
VAL A 107
ILE A 204
MET A 169
 None
 1.35A 1linA-1lajA:
undetectable		 1linA-1lajA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		4 / 5 VAL A 186
TYR A 187
ASP A 190
SER A 119
 None
 1.19A 2x45A-1lajA:
0.0		 2x45A-1lajA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		4 / 5 VAL A 186
TYR A 187
ASP A 190
SER A 119
 None
 1.20A 2x45C-1lajA:
0.0		 2x45C-1lajA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		5 / 11 PHE A 117
SER A 119
VAL A 149
PHE A 143
VAL A 186
 None
 1.40A 3u9fM-1lajA:
0.0
3u9fO-1lajA:
0.0		 3u9fM-1lajA:
21.48
3u9fO-1lajA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		4 / 8 PRO A 161
LEU A 150
VAL A 186
LEU A 111
 None
 1.02A 4pwdA-1lajA:
undetectable		 4pwdA-1lajA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		3 / 3 SER A 119
ASP A  74
ASP A 196
 None
 0.82A 4uckA-1lajA:
undetectable		 4uckA-1lajA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1laj CAPSID PROTEIN
(Tomato
aspermy
virus) 		3 / 3 ASN A 112
LEU A 150
PHE A  58
 None
 0.81A 5dsgA-1lajA:
undetectable		 5dsgA-1lajA:
19.32