SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		5 / 12 LEU A 120
LEU A 117
LEU A 114
ALA A 113
LEU A  26
 None
 0.68A 1s9pC-1lb3A:
undetectable		 1s9pC-1lb3A:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		5 / 10 TYR A 137
ALA A  18
LEU A  23
GLN A  73
PHE A  72
 None
 1.28A 1uhoA-1lb3A:
undetectable		 1uhoA-1lb3A:
20.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		5 / 6 LEU A  28
SER A  31
TYR A  32
LEU A  35
ARG A  63
 None
 0.19A 3f33A-1lb3A:
29.1		 3f33A-1lb3A:
81.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		5 / 6 LEU A  28
SER A  31
TYR A  32
ALA A  59
ARG A  63
 None
 0.22A 3ravA-1lb3A:
29.3		 3ravA-1lb3A:
81.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		5 / 6 LEU A  28
SER A  31
TYR A  32
ALA A  59
ARG A  63
 None
 0.19A 3rd0A-1lb3A:
29.3		 3rd0A-1lb3A:
81.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		4 / 7 LEU A 110
PRO A  88
SER A  89
VAL A  85
 None
 1.11A 4klrA-1lb3A:
0.0		 4klrA-1lb3A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O79_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		4 / 6 LYS A 140
TYR A 137
ARG A  68
ALA A  66
 None
 1.41A 4o79B-1lb3A:
4.7		 4o79B-1lb3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		4 / 6 LYS A 140
TYR A 137
ARG A  68
ALA A  66
 None
 1.39A 4o7gB-1lb3A:
3.1		 4o7gB-1lb3A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 1lb3 FERRITIN LIGHT CHAIN
1
(Mus
musculus) 		4 / 6 HIS A  27
ASN A 109
LEU A 133
GLN A 112
 None
 1.45A 5xdhA-1lb3A:
0.2
5xdhC-1lb3A:
undetectable		 5xdhA-1lb3A:
19.48
5xdhC-1lb3A:
19.48