SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
5 / 9 GLY A  71
GLY A  78
PHE A  15
SER A  76
GLY A  66
None
1.28A 1jhrA-1lbaA:
undetectable
1jhrA-1lbaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
5 / 8 GLY A  71
GLY A  78
PHE A  15
SER A  76
GLY A  66
None
1.27A 1jhvA-1lbaA:
undetectable
1jhvA-1lbaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
5 / 9 GLY A  71
GLY A  78
PHE A  15
SER A  76
GLY A  66
None
1.25A 1jhyA-1lbaA:
undetectable
1jhyA-1lbaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
5 / 9 GLY A  71
GLY A  78
PHE A  15
SER A  76
GLY A  66
None
1.26A 1l4nA-1lbaA:
undetectable
1l4nA-1lbaA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
4 / 6 ASN A  94
ARG A  52
ILE A  85
GLY A  84
None
1.08A 1oniA-1lbaA:
undetectable
1oniB-1lbaA:
undetectable
1oniA-1lbaA:
21.82
1oniB-1lbaA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
4 / 6 ASN A  94
ARG A  52
ILE A  85
GLY A  84
None
1.12A 1oniD-1lbaA:
undetectable
1oniF-1lbaA:
0.0
1oniD-1lbaA:
21.82
1oniF-1lbaA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
4 / 6 VAL A 145
LEU A 144
PHE A  95
MET A 100
None
1.18A 1x8vA-1lbaA:
undetectable
1x8vA-1lbaA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
4 / 8 GLY A  54
PHE A 133
ILE A  50
SER A 102
None
1.05A 2a8tB-1lbaA:
0.0
2a8tB-1lbaA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
3 / 3 LYS A  22
PRO A  23
SER A  24
None
0.28A 4k50I-1lbaA:
undetectable
4k50I-1lbaA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
5 / 9 GLY A  71
GLY A  78
PHE A  15
SER A  76
GLY A  66
None
1.28A 4kqiA-1lbaA:
undetectable
4kqiA-1lbaA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
5 / 12 ALA A 121
PHE A 133
THR A 146
ASN A 142
ARG A 104
None
1.36A 4z7fC-1lbaA:
0.0
4z7fC-1lbaA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
3 / 3 ASN A  94
PRO A  23
GLN A  25
None
0.75A 6jnhA-1lbaA:
1.0
6jnhA-1lbaA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
1lba T7 LYSOZYME
(Escherichia
virus
T7)
3 / 3 ASN A  94
PRO A  23
GLN A  25
None
0.76A 6jogA-1lbaA:
1.0
6jogA-1lbaA:
22.83