SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.72A 1rjoA-1lbuA:
2.1		 1rjoA-1lbuA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 10 ALA A 110
ALA A 112
VAL A 133
LEU A 119
ASP A  80
 None
 1.12A 1rlbE-1lbuA:
0.0		 1rlbE-1lbuA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.27A 1usqB-1lbuA:
undetectable		 1usqB-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.27A 1usqC-1lbuA:
undetectable		 1usqC-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.27A 1usqD-1lbuA:
undetectable		 1usqD-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.27A 1usqE-1lbuA:
undetectable		 1usqE-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 7 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.28A 1usqF-1lbuA:
undetectable		 1usqF-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.68A 1w2zA-1lbuA:
2.3		 1w2zA-1lbuA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.71A 1w2zC-1lbuA:
2.2		 1w2zC-1lbuA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 ALA A 171
ALA A 176
PRO A 187
GLY A 168
TYR A 189
 None
 1.27A 2igtC-1lbuA:
undetectable		 2igtC-1lbuA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.28A 2jkjA-1lbuA:
undetectable		 2jkjA-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.28A 2jkjB-1lbuA:
undetectable		 2jkjB-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.28A 2jkjC-1lbuA:
undetectable		 2jkjC-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 7 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.29A 2jkjE-1lbuA:
undetectable		 2jkjE-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 6 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.26A 2jklB-1lbuA:
undetectable		 2jklB-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 7 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.26A 2jklE-1lbuA:
undetectable		 2jklE-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.72A 2oqeA-1lbuA:
undetectable		 2oqeA-1lbuA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.72A 2oqeB-1lbuA:
undetectable		 2oqeB-1lbuA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.71A 2oqeD-1lbuA:
undetectable		 2oqeD-1lbuA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		3 / 3 HIS A 192
HIS A 195
HIS A 197
 None
None
ZN  A 214 ( 3.3A)
 0.71A 2w0qB-1lbuA:
undetectable		 2w0qB-1lbuA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 5 HIS A 195
HIS A 192
ASP A 161
HIS A 197
 None
None
ZN  A 214 ( 2.3A)
ZN  A 214 ( 3.3A)
 0.94A 3c0zA-1lbuA:
undetectable		 3c0zA-1lbuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 6 HIS A 195
HIS A 192
ASP A 161
HIS A 197
 None
None
ZN  A 214 ( 2.3A)
ZN  A 214 ( 3.3A)
 0.96A 3c0zC-1lbuA:
undetectable		 3c0zC-1lbuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 GLY A  13
ILE A  64
GLY A  63
GLN A  54
THR A  69
 None
 1.11A 3eeyC-1lbuA:
undetectable		 3eeyC-1lbuA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 GLY A  13
ILE A  64
GLY A  63
GLN A  54
THR A  69
 None
 1.10A 3eeyE-1lbuA:
undetectable		 3eeyE-1lbuA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 GLY A  13
ILE A  64
GLY A  63
GLN A  54
THR A  69
 None
 1.11A 3eeyF-1lbuA:
undetectable		 3eeyF-1lbuA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.42A 3g1uA-1lbuA:
undetectable		 3g1uA-1lbuA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 5 THR A  69
ILE A  73
PHE A  53
LEU A  22
 None
 1.37A 3tf1A-1lbuA:
1.6		 3tf1A-1lbuA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 7 ILE A 184
HIS A 179
ALA A 176
ALA A 208
 None
 0.77A 4g77A-1lbuA:
undetectable		 4g77A-1lbuA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 7 ASN A 143
VAL A 146
GLY A 191
ARG A 138
 None
None
None
ZN  A 214 ( 4.6A)
 0.88A 5fpdB-1lbuA:
undetectable		 5fpdB-1lbuA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 6 PRO A  67
THR A  69
ASN A  71
LYS A  72
 None
 0.67A 5xxiA-1lbuA:
undetectable		 5xxiA-1lbuA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.39A 6aphA-1lbuA:
undetectable		 6aphA-1lbuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		4 / 7 ASP A  97
SER A  99
GLY A 100
VAL A 140
 None
 0.95A 6ekzA-1lbuA:
undetectable		 6ekzA-1lbuA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.39A 6f3mA-1lbuA:
0.0		 6f3mA-1lbuA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.39A 6f3mC-1lbuA:
0.0		 6f3mC-1lbuA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.38A 6f3nA-1lbuA:
undetectable		 6f3nA-1lbuA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.44A 6f3nC-1lbuA:
undetectable		 6f3nC-1lbuA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 12 THR A 115
GLU A 183
LEU A 162
GLY A 136
HIS A 154
 None
None
None
None
ZN  A 214 ( 3.3A)
 1.37A 6f3nD-1lbuA:
undetectable		 6f3nD-1lbuA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE
(Streptomyces
albus) 		5 / 10 GLY A  13
GLY A  43
GLN A  23
VAL A  19
GLU A  12
 None
 1.15A 6nqaK-1lbuA:
undetectable		 6nqaK-1lbuA:
18.89