SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lbz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		4 / 4 ASP A  32
GLY A  34
LYS A  43
GLU A  68
 None
None
None
CA  A 292 ( 4.4A)
 1.33A 3hznD-1lbzA:
undetectable		 3hznD-1lbzA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 117
VAL A  77
ILE A  13
LEU A  57
VAL A  62
 None
 1.17A 3w68C-1lbzA:
undetectable		 3w68C-1lbzA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		3 / 3 GLU A 241
THR A 216
HIS A 244
 None
 0.72A 4q15A-1lbzA:
0.0		 4q15A-1lbzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		3 / 3 GLU A 241
THR A 216
HIS A 244
 None
 0.71A 4q15B-1lbzA:
undetectable		 4q15B-1lbzA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  81
ALA A  53
VAL A  17
ALA A  49
ILE A  13
 None
 1.05A 4x1yD-1lbzA:
undetectable		 4x1yD-1lbzA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		3 / 3 GLU A 241
THR A 216
HIS A 244
 None
 0.76A 4ydqB-1lbzA:
undetectable		 4ydqB-1lbzA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGG_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		5 / 12 TYR A 199
THR A  42
ARG A 197
VAL A  65
VAL A  64
 None
 1.49A 5wggA-1lbzA:
undetectable		 5wggA-1lbzA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WHY_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 1lbz FRUCTOSE
1,6-BISPHOSPHATASE/I
NOSITOL
MONOPHOSPHATASE
(Archaeoglobus
fulgidus) 		5 / 11 TYR A 199
THR A  42
ARG A 197
VAL A  65
VAL A  64
 None
 1.45A 5whyA-1lbzA:
0.0		 5whyA-1lbzA:
21.46