SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ld9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM8_A_ACAA511_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1ld9	MHC CLASS I H-2LD HEAVY CHAIN (Mus musculus)	4 / 8	TYR A 123 TYR A 84 TYR A 118 HIS A 93	None	0.91A	2zm8A-1ld9A: 0.0	2zm8A-1ld9A: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_M_TFPM201_1 (PROTEIN S100-A4)	1ld9	MHC CLASS I H-2LD HEAVY CHAIN (Mus musculus)	4 / 7	GLY A 237 PHE A 241 GLY A 207 PHE A 208	None	0.87A	3ko0M-1ld9A: 0.0 3ko0P-1ld9A: undetectable	3ko0M-1ld9A: 15.15 3ko0P-1ld9A: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PFG_A_SAMA264_1 (N-METHYLTRANSFERASE)	1ld9	MHC CLASS I H-2LD HEAVY CHAIN (Mus musculus)	3 / 3	TYR A 171 TYR A 7 GLU A 166	None	0.74A	3pfgA-1ld9A: undetectable	3pfgA-1ld9A: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_B_DXCB92_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1ld9	MHC CLASS I H-2LD HEAVY CHAIN (Mus musculus)	4 / 5	VAL A 25 VAL A 34 ARG A 35 LYS A 68	None	1.31A	3rv5A-1ld9A: undetectable 3rv5B-1ld9A: undetectable	3rv5A-1ld9A: 14.77 3rv5B-1ld9A: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_2 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	1ld9	MHC CLASS I H-2LD HEAVY CHAIN (Mus musculus)	4 / 4	VAL A 165 LEU A 168 LEU A 172 ASP A 29	None	1.39A	5xv7A-1ld9A: 0.8	5xv7A-1ld9A: 17.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZM8_A_ACAA511_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1ld9","MHC CLASS I H-2LD HEAVY CHAIN","Mus musculus",4,"TYR A 123;TYR A  84;TYR A 118;HIS A  93","None","0.91A","2zm8A-1ld9A:0.0","2zm8A-1ld9A:22.68"],["3KO0_M_TFPM201_1","PROTEIN S100-A4;PROTEIN S100-A4","1ld9","MHC CLASS I H-2LD HEAVY CHAIN","Mus musculus",4,"GLY A 237;PHE A 241;GLY A 207;PHE A 208","None","0.87A","3ko0M-1ld9A:0.0;3ko0P-1ld9A:undetectable","3ko0M-1ld9A:15.15;3ko0P-1ld9A:15.15"],["3PFG_A_SAMA264_1","N-METHYLTRANSFERASE","1ld9","MHC CLASS I H-2LD HEAVY CHAIN","Mus musculus",3,"TYR A 171;TYR A   7;GLU A 166","None","0.74A","3pfgA-1ld9A:undetectable","3pfgA-1ld9A:21.90"],["3RV5_B_DXCB92_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1ld9","MHC CLASS I H-2LD HEAVY CHAIN","Mus musculus",4,"VAL A  25;VAL A  34;ARG A  35;LYS A  68","None","1.31A","3rv5A-1ld9A:undetectable;3rv5B-1ld9A:undetectable","3rv5A-1ld9A:14.77;3rv5B-1ld9A:14.77"],["5XV7_A_EMHA705_2","SERINE-ARGININE (SR) PROTEIN KINASE 1","1ld9","MHC CLASS I H-2LD HEAVY CHAIN","Mus musculus",4,"VAL A 165;LEU A 168;LEU A 172;ASP A  29","None","1.39A","5xv7A-1ld9A:0.8","5xv7A-1ld9A:17.52"]]