SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ldd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 1ldd ANAPHASE PROMOTING
COMPLEX
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 826
ASN A 827
LEU A 829
ALA A 830
LEU A 789
 None
 0.79A 2aa6A-1lddA:
undetectable		 2aa6A-1lddA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 1ldd ANAPHASE PROMOTING
COMPLEX
(Saccharomyces
cerevisiae) 		4 / 6 GLN A 820
LEU A 822
GLU A 823
LEU A 797
 None
 0.88A 3h5gA-1lddA:
undetectable
3h5gC-1lddA:
undetectable		 3h5gA-1lddA:
20.00
3h5gC-1lddA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1ldd ANAPHASE PROMOTING
COMPLEX
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 826
LEU A 829
ALA A 830
LEU A 789
GLY A 841
 None
 0.98A 3olsA-1lddA:
undetectable		 3olsA-1lddA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1ldd ANAPHASE PROMOTING
COMPLEX
(Saccharomyces
cerevisiae) 		4 / 7 GLU A 832
LEU A 829
TYR A 825
LEU A 782
 None
 0.86A 4iomA-1lddA:
undetectable		 4iomA-1lddA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1ldd ANAPHASE PROMOTING
COMPLEX
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 832
LEU A 829
TYR A 825
LEU A 782
 None
 0.91A 4jjkA-1lddA:
undetectable		 4jjkA-1lddA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 1ldd ANAPHASE PROMOTING
COMPLEX
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 826
LEU A 829
ALA A 830
LEU A 789
GLY A 841
 None
 0.93A 4pxmA-1lddA:
undetectable		 4pxmA-1lddA:
12.45