SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ldi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 10 LEU A 216
ALA A 102
ILE A  22
GLY A  19
GLY A  96
 BOG  A 473 (-4.3A)
BOG  A 473 ( 4.1A)
None
None
None
 1.09A 1k6cA-1ldiA:
undetectable		 1k6cA-1ldiA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 10 GLU A  14
GLY A  61
GLY A  64
ILE A  12
LEU A  16
 None
 1.15A 1x7pA-1ldiA:
undetectable
1x7pB-1ldiA:
undetectable		 1x7pA-1ldiA:
22.44
1x7pB-1ldiA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		3 / 3 GLY A 191
GLY A 199
GLY A 195
 None
 0.41A 3bogC-1ldiA:
undetectable		 3bogC-1ldiA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		3 / 3 GLY A 191
GLY A 199
GLY A 195
 None
 0.40A 3bogD-1ldiA:
undetectable		 3bogD-1ldiA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		4 / 4 GLY A 227
VAL A 222
GLY A 133
THR A 134
 None
 0.69A 3ib2A-1ldiA:
0.0		 3ib2A-1ldiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		4 / 5 LEU A 131
THR A 134
GLU A 116
HIS A 119
 None
 1.50A 3n58C-1ldiA:
undetectable		 3n58C-1ldiA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 11 LEU A  58
ALA A  65
GLU A  14
LEU A  67
GLY A  51
 None
 1.25A 3uudA-1ldiA:
0.1		 3uudA-1ldiA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 10 GLY A  51
ALA A  55
ILE A  56
ILE A 163
LEU A 159
 None
 1.09A 4dt8B-1ldiA:
undetectable		 4dt8B-1ldiA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		4 / 6 ILE A  90
PHE A  89
ILE A 163
ILE A 241
 None
 0.70A 4o8fB-1ldiA:
undetectable		 4o8fB-1ldiA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 164
ILE A 183
ILE A  56
GLY A  64
ILE A 163
 None
 1.04A 4q1yB-1ldiA:
undetectable		 4q1yB-1ldiA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 247
GLY A 243
ILE A 158
MET A 153
ALA A 250
 None
 0.97A 4qtuB-1ldiA:
undetectable		 4qtuB-1ldiA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 247
GLY A 243
ILE A 158
MET A 153
ALA A 250
 None
 0.96A 4qtuD-1ldiA:
undetectable		 4qtuD-1ldiA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 238
GLY A 239
GLY A 243
THR A 198
 None
 0.74A 5ybbB-1ldiA:
undetectable		 5ybbB-1ldiA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 1ldi GLYCEROL UPTAKE
FACILITATOR PROTEIN
(Escherichia
coli) 		4 / 6 ARG A 206
SER A 136
ALA A 214
ALA A 100
 None
 1.15A 6ma6A-1ldiA:
2.3		 6ma6A-1ldiA:
14.91