SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ldm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		6 / 9 VAL A  26
GLY A  27
ASP A  52
TYR A  83
ALA A  96
ILE A 116
 None
NAD  A 330 ( 4.3A)
NAD  A 330 (-2.8A)
None
NAD  A 330 (-3.4A)
NAD  A 330 ( 4.1A)
 0.69A 1cetA-1ldmA:
38.2		 1cetA-1ldmA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		5 / 11 THR A  24
VAL A  93
ILE A  94
ASN A 123
ILE A 124
 None
 1.19A 3kpcA-1ldmA:
0.0		 3kpcA-1ldmA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		4 / 8 PRO A 269
SER A 287
VAL A 270
GLY A 187
 None
 1.01A 4mk4A-1ldmA:
3.1		 4mk4A-1ldmA:
20.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		6 / 9 ASP A  52
TYR A  83
ALA A  96
ARG A  99
ILE A 116
ILE A 120
 NAD  A 330 (-2.8A)
None
NAD  A 330 (-3.4A)
NAD  A 330 (-4.0A)
NAD  A 330 ( 4.1A)
None
 1.47A 4oknB-1ldmA:
47.1		 4oknB-1ldmA:
77.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		5 / 9 ASP A  52
TYR A  83
ALA A  96
ARG A 112
ILE A 120
 NAD  A 330 (-2.8A)
None
NAD  A 330 (-3.4A)
None
None
 1.04A 4oknB-1ldmA:
47.1		 4oknB-1ldmA:
77.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		6 / 9 ASP A  52
VAL A  53
TYR A  83
ALA A  96
ILE A 116
ILE A 120
 NAD  A 330 (-2.8A)
NAD  A 330 (-4.2A)
None
NAD  A 330 (-3.4A)
NAD  A 330 ( 4.1A)
None
 0.40A 4oknB-1ldmA:
47.1		 4oknB-1ldmA:
77.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 1ldm M4 LACTATE
DEHYDROGENASE
(Squalus
acanthias) 		5 / 12 VAL A  93
ILE A  23
SER A  89
SER A 128
VAL A  51
 None
 1.44A 4rujA-1ldmA:
0.0		 4rujA-1ldmA:
21.41