SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lfp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.93A 1dz4A-1lfpA:
0.0
1dz4A-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 1dz4B-1lfpA:
0.0
1dz4B-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
5 / 11 VAL A 130
TYR A  90
GLY A 122
LEU A 221
VAL A 207
None
1.44A 1i9jH-1lfpA:
undetectable
1i9jL-1lfpA:
undetectable
1i9jH-1lfpA:
22.02
1i9jL-1lfpA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 8 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.92A 1iwiA-1lfpA:
undetectable
1iwiA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.87A 1t85A-1lfpA:
undetectable
1t85A-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 8 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 1t86A-1lfpA:
undetectable
1t86A-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.93A 1t87A-1lfpA:
undetectable
1t87A-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.96A 1t87B-1lfpA:
undetectable
1t87B-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 5 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 1t88B-1lfpA:
0.0
1t88B-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 1yrcA-1lfpA:
undetectable
1yrcA-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.87A 1yrdA-1lfpA:
0.0
1yrdA-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 8 LEU A 124
VAL A  85
VAL A 234
VAL A 116
None
0.80A 2bdmA-1lfpA:
undetectable
2bdmA-1lfpA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.90A 2cppA-1lfpA:
undetectable
2cppA-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.84A 2feuA-1lfpA:
undetectable
2feuA-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.86A 2feuB-1lfpA:
undetectable
2feuB-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 5 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.90A 2m56A-1lfpA:
0.0
2m56A-1lfpA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 2qblA-1lfpA:
0.0
2qblA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 2zaxA-1lfpA:
undetectable
2zaxA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.99A 2zuhA-1lfpA:
0.0
2zuhA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.91A 2zuiA-1lfpA:
0.0
2zuiA-1lfpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 2zwtA-1lfpA:
0.0
2zwtA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 2zwuA-1lfpA:
0.0
2zwuA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.86A 3fwfA-1lfpA:
undetectable
3fwfA-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 3fwfB-1lfpA:
undetectable
3fwfB-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.86A 3fwgA-1lfpA:
undetectable
3fwgA-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 3fwgB-1lfpA:
undetectable
3fwgB-1lfpA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 3fwiA-1lfpA:
undetectable
3fwiA-1lfpA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.86A 3fwjA-1lfpA:
0.0
3fwjA-1lfpA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.84A 3l63A-1lfpA:
0.0
3l63A-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.87A 3wrhA-1lfpA:
undetectable
3wrhA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.87A 3wrhE-1lfpA:
0.0
3wrhE-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 3wrjA-1lfpA:
0.0
3wrjA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 3wrjE-1lfpA:
0.0
3wrjE-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.85A 3wrlA-1lfpA:
undetectable
3wrlA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 3wrlE-1lfpA:
0.0
3wrlE-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.89A 3wrmA-1lfpA:
0.0
3wrmA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 3wrmF-1lfpA:
undetectable
3wrmF-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.86A 4ek1A-1lfpA:
undetectable
4ek1A-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.86A 4g3rA-1lfpA:
undetectable
4g3rA-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.85A 4g3rB-1lfpA:
0.0
4g3rB-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 8 ILE A 209
LYS A 220
ILE A 219
GLY A 122
None
0.93A 4hdlA-1lfpA:
0.0
4hdlA-1lfpA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.93A 4kkyX-1lfpA:
0.0
4kkyX-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 5 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.85A 4l49A-1lfpA:
0.0
4l49A-1lfpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 8 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.88A 4l4aA-1lfpA:
undetectable
4l4aA-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.82A 4l4cA-1lfpA:
0.0
4l4cA-1lfpA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.83A 4l4gA-1lfpA:
0.0
4l4gA-1lfpA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 SER A  26
ARG A  37
GLY A  73
GLU A  76
None
0.97A 5btaA-1lfpA:
4.3
5btaB-1lfpA:
2.3
5btaC-1lfpA:
4.0
5btaA-1lfpA:
19.79
5btaB-1lfpA:
23.05
5btaC-1lfpA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 SER A  26
ARG A  37
GLY A  73
GLU A  76
None
1.03A 5btcA-1lfpA:
4.4
5btcC-1lfpA:
4.2
5btcD-1lfpA:
2.3
5btcA-1lfpA:
19.79
5btcC-1lfpA:
19.79
5btcD-1lfpA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 SER A  26
ARG A  37
GLY A  73
GLU A  76
None
0.99A 5btcA-1lfpA:
4.3
5btcB-1lfpA:
2.3
5btcC-1lfpA:
4.2
5btcA-1lfpA:
19.79
5btcB-1lfpA:
23.05
5btcC-1lfpA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 SER A  26
ARG A  37
GLY A  73
GLU A  76
None
0.96A 5btfA-1lfpA:
4.2
5btfB-1lfpA:
3.3
5btfC-1lfpA:
4.1
5btfA-1lfpA:
19.79
5btfB-1lfpA:
23.05
5btfC-1lfpA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 4 GLN A  55
THR A  51
THR A 175
LEU A 187
None
1.46A 5m5kA-1lfpA:
undetectable
5m5kA-1lfpA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 4 GLN A  55
THR A  51
THR A 175
LEU A 187
None
1.46A 5m5kC-1lfpA:
undetectable
5m5kC-1lfpA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 4 GLN A  55
THR A  51
THR A 175
LEU A 187
None
1.44A 5m66B-1lfpA:
undetectable
5m66B-1lfpA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 7 PHE A 117
LEU A 222
VAL A 234
VAL A 130
None
0.82A 5wk9A-1lfpA:
undetectable
5wk9A-1lfpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 5 ASN A 107
TYR A  87
VAL A 231
LEU A 225
None
1.07A 6a7pA-1lfpA:
2.3
6a7pA-1lfpA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 6 PHE A  25
ARG A  30
LEU A  28
ALA A  59
None
1.02A 6b89B-1lfpA:
undetectable
6b89B-1lfpA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
3 / 3 ARG A  21
LYS A  23
ARG A 108
None
1.31A 6c06D-1lfpA:
0.0
6c06D-1lfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
5 / 10 GLY A 122
VAL A 234
VAL A  95
ALA A 236
LEU A 225
None
1.15A 6czmA-1lfpA:
5.0
6czmC-1lfpA:
undetectable
6czmA-1lfpA:
22.07
6czmC-1lfpA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus)
4 / 4 GLN A  55
THR A  51
THR A 175
LEU A 187
None
1.46A 6f3mB-1lfpA:
undetectable
6f3mB-1lfpA:
19.83