SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 GLN A 128
ILE A 164
HIS A  90
 None
 0.74A 1fm9A-1lg7A:
0.0		 1fm9A-1lg7A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 TRP A 190
VAL A 221
PRO A 142
 None
 0.95A 1rg1A-1lg7A:
undetectable		 1rg1A-1lg7A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 TRP A 190
VAL A 221
PRO A 142
 None
 0.97A 1rh0A-1lg7A:
undetectable		 1rh0A-1lg7A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 ASP A 223
THR A 148
PRO A 149
 None
 0.59A 2pynB-1lg7A:
undetectable		 2pynB-1lg7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 ASP A 223
THR A 148
PRO A 149
 None
 0.63A 2q64B-1lg7A:
undetectable		 2q64B-1lg7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 ASP A 223
THR A 148
PRO A 149
 None
 0.57A 2qakB-1lg7A:
undetectable		 2qakB-1lg7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		5 / 11 SER A 113
TRP A 190
LEU A 141
GLY A 209
PHE A 208
 None
 1.20A 4fogA-1lg7A:
0.0		 4fogA-1lg7A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 HIS A 134
VAL A  88
LEU A 173
 CSO  A 135 ( 4.4A)
None
None
 0.54A 4m2vA-1lg7A:
undetectable		 4m2vA-1lg7A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		3 / 3 GLN A 128
ILE A 164
HIS A  90
 None
 0.70A 5z12B-1lg7A:
undetectable		 5z12B-1lg7A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 1lg7 VSV MATRIX PROTEIN
(Vesicular
stomatitis
virus) 		4 / 7 GLY A 218
TRP A 220
ASP A 191
TRP A 190
 None
 1.50A 6ag0C-1lg7A:
undetectable		 6ag0C-1lg7A:
19.66