SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lgb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1lgb LACTOTRANSFERRIN (N2
FRAGMENT)
(Homo
sapiens) 		4 / 8 SER C 185
SER C 184
GLY C 160
GLY C 175
 None
 0.69A 1me7A-1lgbC:
undetectable		 1me7A-1lgbC:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 1lgb LACTOTRANSFERRIN (N2
FRAGMENT)
(Homo
sapiens) 		4 / 8 SER C 185
SER C 184
GLY C 160
GLY C 175
 None
 0.84A 4fo4B-1lgbC:
undetectable		 4fo4B-1lgbC:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 1lgb LACTOTRANSFERRIN (N2
FRAGMENT)
(Homo
sapiens) 		5 / 9 VAL C 206
ALA C 207
GLY C 111
SER C 156
GLY C 204
 None
 1.24A 4mmfA-1lgbC:
undetectable		 4mmfA-1lgbC:
16.20