SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lgh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		3 / 3 ALA B  34
HIS B  35
VAL B  38
 BCL  A  57 ( 3.7A)
BCL  B  59 (-3.5A)
DET  B  77 ( 4.5A)
 0.32A 1lqtB-1lghB:
undetectable		 1lqtB-1lghB:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		3 / 3 ALA B  34
HIS B  35
VAL B  38
 BCL  A  57 ( 3.7A)
BCL  B  59 (-3.5A)
DET  B  77 ( 4.5A)
 0.32A 1lquB-1lghB:
undetectable		 1lquB-1lghB:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		4 / 4 ALA A  32
ALA A  35
ALA A  36
ALA A  39
 LYC  A  97 ( 3.6A)
HTO  A  62 (-3.9A)
LYC  A  97 ( 3.0A)
DET  A  75 ( 3.7A)
 0.11A 4oadA-1lghA:
undetectable		 4oadA-1lghA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		4 / 4 ALA A  32
ALA A  35
ALA A  36
ALA A  39
 LYC  A  97 ( 3.6A)
HTO  A  62 (-3.9A)
LYC  A  97 ( 3.0A)
DET  A  75 ( 3.7A)
 0.09A 4oaeA-1lghA:
undetectable		 4oaeA-1lghA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		4 / 9 ALA B  15
LEU B   8
LEU A  11
ILE A   9
 LYC  A  97 ( 2.7A)
None
None
BCL  A  58 (-4.0A)
 0.85A 4xtaA-1lghB:
undetectable		 4xtaA-1lghB:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1lgh LIGHT HARVESTING
COMPLEX II
LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum;
Phaeospirillum
molischianum) 		4 / 4 ILE A  13
LEU B   8
HIS B  17
ALA B  13
 None
None
BCL  A  58 ( 4.1A)
None
 1.04A 6ck2C-1lghA:
undetectable
6ck2D-1lghA:
undetectable		 6ck2C-1lghA:
8.93
6ck2D-1lghA:
14.29