SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lht'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 1lht MYOGLOBIN
(Caretta
caretta) 		5 / 12 LEU A  72
LEU A  69
VAL A  68
LEU A 104
HIS A  93
 HEM  A 155 ( 4.5A)
None
HEM  A 155 ( 4.0A)
HEM  A 155 ( 4.6A)
HEM  A 155 (-3.4A)
 1.30A 3m7rA-1lhtA:
0.0		 3m7rA-1lhtA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 1lht MYOGLOBIN
(Caretta
caretta) 		4 / 6 ASP A 141
ASN A 140
ALA A 143
TYR A 146
 None
 1.14A 4mdaA-1lhtA:
undetectable		 4mdaA-1lhtA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 1lht MYOGLOBIN
(Caretta
caretta) 		3 / 3 GLU A  27
HIS A  24
VAL A 114
 None
 0.88A 5trqB-1lhtA:
undetectable		 5trqB-1lhtA:
18.58