SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1lk0 ARSENATE REDUCTASE
(Staphylococcus
aureus) 		4 / 4 LEU A  72
ALA A  37
ILE A   9
LYS A  73
 None
 1.45A 4eixA-1lk0A:
1.5		 4eixA-1lk0A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1lk0 ARSENATE REDUCTASE
(Staphylococcus
aureus) 		3 / 3 ALA A  85
ASN A  88
LEU A  89
 None
 0.23A 5i1nC-1lk0A:
undetectable		 5i1nC-1lk0A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1lk0 ARSENATE REDUCTASE
(Staphylococcus
aureus) 		3 / 3 ALA A  85
ASN A  88
LEU A  89
 None
 0.24A 5i1oC-1lk0A:
0.0		 5i1oC-1lk0A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1lk0 ARSENATE REDUCTASE
(Staphylococcus
aureus) 		3 / 3 ALA A  85
ASN A  88
LEU A  89
 None
 0.21A 5i1pA-1lk0A:
0.0		 5i1pA-1lk0A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1lk0 ARSENATE REDUCTASE
(Staphylococcus
aureus) 		3 / 3 ALA A  85
ASN A  88
LEU A  89
 None
 0.33A 5i1pD-1lk0A:
undetectable		 5i1pD-1lk0A:
24.24